Lysodren (Mitotane) Tablets 500mg - Treat Adrenal Cortical Carcinoma

Lysodren Tablets for Adrenal Cortical Carcinoma Treatment 

Lysodren (brand name for Mitotane) is an anticancer medication that is used to treat hyperadrenocorticism (Cushing’s disease) or adrenal gland carcinoma. In dogs, Cushing's disease occurs naturally and is either pituitary-dependent or adrenal-dependent. About 80% to 85% of Cushing's is pituitary-dependent, meaning it's triggered by a tumor on the pituitary, a pea-sized gland at the base of the brain.

Lysodren destroys the layers of the adrenal gland that produce cortisol. It requires careful monitoring and can have severe side effects.    Treatment with mitotane involves an initiating phase and a maintenance phase. The initiating phase arrests the disease and restores the dog to a more normal state. 

All prescription items are Non-Refundable and Non-Returnable.

Benefits of Lysodren Tablets

• Targeted Action: Specifically addresses adrenal cortical carcinoma, improving outcomes in affected pets.
• Tumor Reduction: Helps shrink adrenal tumors, alleviating related symptoms.
• Hormonal Balance: Reduces excess hormone production, leading to better overall health.
• Quality of Life: By managing the disease, Lysodren helps improve your pet's comfort and well-being.
  

Subscription and Purchase Information

Buying Options and Discounts: Purchase Lysodren (Mitotane) Tablets in a convenient 1, 2, 3, and 6-month supply pack. Subscribe for regular shipments to ensure you never miss a dose and enjoy discounts on your purchases.
Order online for hassle-free delivery to your doorstep.

Ingredients in Lysodren 500mg Tablets

Lysodren contains the active ingredient Mitotane, a derivative of DDT that targets adrenal cortex cells, leading to their destruction. The inactive ingredients vary depending on the manufacturer but typically include fillers and binders that stabilize the tablet form.

How Lysodren (Mitotane) 500mg Tablets Work

Mitotane, the active ingredient in Lysodren, works by selectively destroying the cells of the adrenal cortex. This action reduces the production of corticosteroids, which are often overproduced in adrenal cortical carcinoma. By lowering these hormone levels, Lysodren helps to control the symptoms and progression of the disease.

Dosage and Administration 

Frequency

Administer Lysodren exactly as prescribed by your veterinarian, typically once or twice daily, depending on the severity of the condition. The dosage may need to be adjusted based on the pet’s response and side effects.

Consistency

Consistency is key to effective treatment. Ensure the medication is given at the same time each day, ideally with food to enhance absorption and reduce gastrointestinal upset.

Lysodren Side Effects 

While Lysodren is effective, it may cause side effects that require careful monitoring. Common side effects include lethargy, vomiting, and diarrhea. In rare cases, more severe reactions like liver damage or neurological symptoms may occur.

Precautions

Regular blood tests are essential to monitor the effects of Lysodren and adjust the dosage if necessary. Ensure your pet stays hydrated and maintains a balanced diet during treatment.

Warnings

Lysodren should not be used in pets with known hypersensitivity to Mitotane. Pregnant or lactating pets should only use this medication if the benefits outweigh the risks.

Contraindications

Do not use Lysodren in pets with severe liver or kidney disease, as the medication may exacerbate these conditions. Additionally, avoid use if your pet is already taking anticoagulants, as interactions can occur.

Storage

Store Lysodren (Mitotane) 500mg tablets at room temperature, away from moisture and light. Keep the medication out of reach of children and pets.

Shipping & Returns

Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

FAQs About Lysodren Mitotane Tablets

Q: What is Lysodren (Mitotane) 500mg Tablets used for?

A: Lysodren (Mitotane) 500mg tablets are used to treat adrenal cortical carcinoma in pets by targeting and destroying adrenal cortex cells, reducing excessive hormone production, and helping to shrink tumors.

Q: How long does it take to see results with Lysodren?

A: Results vary, but many pets show improvement within weeks. Regular monitoring by a veterinarian is essential to adjust dosages and evaluate the treatment's effectiveness.

Q: Can Lysodren be used alongside other medications?

A: Lysodren may interact with certain medications, including anticoagulants and corticosteroids. Always inform your vet about all the medications your pet is taking to avoid adverse interactions.

Q: What are the signs of Lysodren overdose?

A: Signs of an overdose include severe lethargy, vomiting, loss of coordination, and a significant drop in appetite. If you suspect an overdose, seek emergency veterinary care immediately.

Q: Is there a special diet required while my pet is on Lysodren?

A: No specific diet is required, but feeding Lysodren with food can help reduce gastrointestinal upset and improve absorption. Always follow your veterinarian’s advice on dietary management during treatment.

Q: How should I monitor my pet while they are on Lysodren?

A: Regular blood tests are necessary to monitor adrenal function and hormone levels. Watch for signs of side effects like vomiting, diarrhea, or changes in behavior and report them to your vet promptly.

Q: Can Lysodren be used for conditions other than adrenal cortical carcinoma?

A: While primarily used for adrenal cortical carcinoma, Lysodren may be prescribed off-label for other conditions. Consult your veterinarian for specific uses based on your pet’s condition.

Q: What should I do if I miss giving my pet a dose of Lysodren?

A: If you miss a dose, give it as soon as you remember, unless it's close to the next scheduled dose. In that case, skip the missed dose and resume the regular schedule. Do not double the dose.

Q: Are there long-term effects of using Lysodren on pets?

A: Long-term use of Lysodren can lead to adrenal insufficiency or liver issues. Regular veterinary check-ups are crucial to monitor for these potential side effects and adjust the treatment as needed.

Q: Can Lysodren be used in pregnant pets?

A: Lysodren should be used with caution in pregnant or lactating pets. The risks and benefits must be weighed carefully, so always discuss with your veterinarian before administering.

Clinical Research:

https://link.springer.com/article/10.1007/s40267-022-00958-y