Advantage Multi Topical for Dogs 55.1-88 lbs Blue
Broad-Spectrum Parasite Protection
Advantage Multi Topical for Dogs 55.1-88 lbs Blue is a veterinarian-recommended monthly treatment formulated to provide comprehensive protection against heartworms, fleas, hookworms, roundworms, whipworms, and sarcoptic mange in medium-to-large dogs. This easy-to-apply topical solution uses a dual-active formula combining Imidacloprid and Moxidectin—powerful ingredients that kill parasites on contact and prevent reinfestation.
Perfect for dogs weighing between 55.1 to 88 pounds, Advantage Multi Blue is designed for ongoing parasite prevention while supporting your pet’s long-term health. Whether you're safeguarding your dog from deadly heartworm disease or controlling flea infestations, this topical solution ensures year-round, hassle-free protection.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.
Also Available in Other Weight Ranges
Looking for the right dose of Advantage Multi for your dog’s specific weight? Explore the full range of vet-recommended flea, heartworm, and worm protection tailored to different sizes:
- Advantage Multi for Dogs 3-9 lbs (Green) – For extra-small breeds and puppies
- Advantage Multi for Dogs 9.1-20 lbs (Teal) – Perfect for small breeds
- Advantage Multi for Dogs 20.1-55 lbs (Red) – Ideal for medium-sized dogs
- Advantage Multi for Dogs 55.1-88 lbs (Blue) – Designed for large dogs (you are viewing this product)
- Advantage Multi for Dogs 88.1-110 lbs (Brown) – For extra-large breeds
Each formula delivers broad-spectrum parasite protection, combining Imidacloprid and Moxidectin in weight-specific doses for optimal safety and effectiveness.
What Are the Key Benefits of Advantage Multi for Dogs 55.1-88 lbs?
Advantage Multi (Imidacloprid + Moxidectin) offers an all-in-one approach to parasite control, eliminating the need for multiple medications.
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Kills adult fleas on contact before they can lay eggs, breaking the flea life cycle
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Prevents heartworm disease caused by Dirofilaria immitis
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Treats and controls intestinal worms, including hookworms, roundworms, and whipworms
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Effective against sarcoptic mange mites, reducing skin irritation and itching
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Water-resistant formulation — remains effective even after bathing or swimming
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Once-a-month topical application — easy and stress-free for both pet and owner
What Are the Active Ingredients in Advantage Multi?
Understanding the core components helps identify how Advantage Multi works:
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Moxidectin is a macrocyclic lactone that paralyzes and kills parasites by disrupting chloride ion channels in nerve cells.
- Imidacloprid is a neonicotinoid insecticide that mimics acetylcholine and overstimulates insect nerves.
How to Use Advantage Multi for Dogs 55.1-88 lbs?
Advantage Multi Topical Solution is a once-a-month treatment that should be applied directly to your dog’s skin. Proper application ensures maximum effectiveness against parasites like fleas, heartworms, and intestinal worms.
Quick Application Guide:
- Apply topically once a month—ideally on the same date.
- Part the fur at the base of your dog’s neck, between the shoulder blades.
- Squeeze the entire contents of one tube directly onto a single spot of exposed skin.
- Do not rub in or spread the medication manually.
- Keep the area dry for 24 hours—no swimming or bathing.
- Prevent your dog from licking or touching the site until fully dry.
🔒 For use only in dogs weighing 55.1–88 lbs. Not for cats or other animals.
How to Apply Advantage Multi Topical Solution for Dogs 55.1–88 lbs – Step-by-Step Instructions
Applying Advantage Multi for Large Dogs correctly helps maintain continuous parasite protection and minimizes any mess or irritation. Follow these veterinarian-approved steps:
Step 1: Prep the Tube
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Take one single-dose tube from the pack.
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Hold upright and twist off the cap.
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Flip the cap over and use its reverse side to pierce the seal on the tube tip.
Step 2: Apply to Skin
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While your dog is standing, part the fur at the base of the neck, between the shoulder blades.
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Make sure the skin is clearly visible—this ensures direct skin contact.
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Touch the tip of the tube to the skin and squeeze gently to dispense the entire contents in one spot only.
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Avoid spreading over multiple areas or applying to broken skin.
Step 3: Post-Application Tips
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Ensure the area remains dry for at least 24 hours.
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Don’t allow your dog to lick or groom the site until fully dry.
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Monitor for any signs of discomfort or skin sensitivity.
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Reapply on the same date each month for uninterrupted flea, heartworm, and worm prevention.
💡 Pro Tip: Wear gloves during application and wash your hands thoroughly afterward to avoid residue contact.
Are There Any Side Effects of Advantage Multi Topical?
While most dogs tolerate Advantage Multi well, some may experience mild reactions:
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Temporary lethargy or decrease in appetite
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Skin irritation at the application site (e.g., redness, itching, or hair loss)
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Neurological signs like trembling or uncoordinated movement (rare)
🐾 If signs persist or worsen, consult your veterinarian immediately.
What Warnings Should I Know Before Using Advantage Multi?
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For dogs only — do not use on cats or other animals
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Safe for dogs over 7 weeks of age and weighing at least 55.1 lbs
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Do not apply to broken skin or if your pet is ill or debilitated
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Keep out of reach of children and avoid contact with eyes and mouth
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Avoid bathing your pet within 24 hours after application
Shipping & Returns
Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.
Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.
Advantage Multi for Dogs 55.1-88 lbs FAQs
Can Advantage Multi be used year-round for parasite prevention?
Yes, Advantage Multi should be applied monthly year-round to maintain continuous protection against fleas, heartworms, and intestinal parasites, especially in warmer climates where pests remain active throughout the year.
Is Advantage Multi safe for pregnant or nursing dogs?
Veterinarians should evaluate use in pregnant or lactating dogs. While studies show limited risk, Moxidectin may require caution depending on your dog's condition. Always consult your vet before starting treatment.
What should I do if my dog accidentally ingests Advantage Multi?
If ingestion occurs, contact your veterinarian or an emergency animal poison control center immediately. While rare, oral exposure may lead to drooling, vomiting, or neurological symptoms in sensitive dogs.
Does Advantage Multi repel ticks or only kill fleas?
Advantage Multi kills fleas and internal parasites but does not repel or kill ticks. For tick control, you may need to use a separate tick-specific preventative approved by your vet alongside Advantage Multi.
How does Advantage Multi compare to Simparica Trio or NexGard Spectra?
Advantage Multi uses a topical formula to kill fleas and prevent heartworm, while Simparica Trio and NexGard Spectra are oral chewables that also target ticks. Choice depends on your dog’s needs and vet recommendation.
Clinical Research
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3fc1a42b-6576-4890-aa0c-5c0eb903c85a
https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/804
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