Apoquel (oclacitinib) Tablets, 16mg

Apoquel (Oclacitinib) Tablets for Allergic Skin Diseases in Dogs

Apoquel (Oclacitinib) Tablets, 16mg, are fast-acting oral medications specifically formulated for dogs suffering from itching and inflammation caused by allergic skin conditions, such as atopic dermatitis and allergic dermatitis.

By directly targeting Janus kinase (JAK) enzymes, Apoquel interrupts the itch and inflammation cycle, providing relief at the source. This makes it highly effective for conditions triggered by flea allergies, food allergies, and environmental irritants. Apoquel works quickly, showing results in as little as 4 hours and achieving full control of itching within 24 hours.

Indications

Apoquel is indicated for the relief of itching and inflammation caused by allergic skin disease (atopy, atopic dermatitis) in dogs 12 months of age or older.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.

What Are the Benefits of Apoquel Tablets?

1. Rapid Relief: Noticeable reduction in itch within 4 hours, with complete control in 24 hours.
2. Targeted Mechanism: Focuses on JAK enzyme pathways to reduce inflammation and itching.
3. Steroid-Free Solution: Avoids the side effects commonly associated with corticosteroids.
4. Versatile Use: Effective for a variety of allergic conditions, including flea allergies, food sensitivities, and contact dermatitis.
5. Safe Long-Term Treatment: Suitable for continuous use under veterinary supervision.

What Are the Ingredients in Apoquel?

• Active Ingredient: Oclacitinib maleate – a JAK inhibitor targeting inflammatory and itch-related pathways.
• Inactive Ingredients: Include excipients for tablet formation

How to Administer Apoquel Tablets?

Dosage and Administration:

• The recommended dosage is 0.18 to 0.27 mg per pound of body weight (0.4 to 0.6 mg/kg).
• Administer orally twice daily for up to 14 days during initial treatment.
• Transition to once daily for maintenance therapy.
• Always follow your veterinarian’s specific instructions for dosing based on your dog's condition and weight.

What Are the Possible Side Effects of Apoquel (Oclacitinib) Tablets?

Apoquel (Oclacitinib) Tablets are generally well-tolerated; however, like any medication, they can cause side effects in some dogs.

Common Side Effects:

• Vomiting and Diarrhea: These are the most frequently reported side effects and are typically mild and self-resolving.
• Lethargy or Anorexia: Some dogs may experience temporary fatigue or loss of appetite.

Potential Serious Risks:

1. Immune System Modulation: Apoquel suppresses immune function, which can increase the risk of:
   • Infections: Dogs may be more susceptible to conditions like demodicosis (a type of mange caused by Demodex mites).
   • Neoplastic Conditions: Treatment has been associated with the development or exacerbation of benign and malignant tumors.
2. Allergic Reactions: Rarely, some dogs may develop an adverse reaction, such as skin irritations or swelling.

Long-Term Risks:

• New neoplastic conditions have been observed in clinical studies and reported during post-approval use.
• Dogs with a history of recurrent infections or cancer should be monitored closely during treatment.

Storage Instructions

• Store at room temperature between 68°F and 77°F.
• Keep away from moisture and direct sunlight.
• Ensure the product is out of reach of children and pets to prevent accidental ingestion.

Shipping & Returns 

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FAQs - Apoquel (Oclacitinib) Tablets for Dogs

What is Apoquel (Oclacitinib) Tablets used for?

Apoquel is prescribed to control itching and inflammation caused by allergic skin conditions in dogs, such as atopic dermatitis and flea, food, or contact allergies. It works by targeting specific pathways in the immune system to provide fast, effective relief.

Can Apoquel be used for long-term treatment?

Yes, Apoquel is suitable for long-term use under veterinary supervision. Regular check-ups are essential to monitor your dog for any potential side effects or risks, such as infections or tumors.

How does Apoquel compare to steroids for allergy relief?

Unlike steroids, Apoquel specifically targets Janus kinase (JAK) enzymes to manage itching and inflammation without suppressing the entire immune system. This reduces the risk of common steroid-related side effects like increased thirst, hunger, or weight gain.

Is Apoquel safe for older dogs?

Apoquel is generally safe for older dogs but should be used with caution in dogs with a history of infections, cancer, or other chronic conditions. Always consult your veterinarian to determine the best treatment plan for senior pets.

Can Apoquel treat seasonal allergies in dogs?

Yes, Apoquel is effective in managing symptoms of seasonal allergies, including itching and inflammation caused by environmental allergens like pollen, dust, and mold.

Are there natural alternatives to Apoquel for itch relief?

Natural alternatives, such as omega-3 fatty acids, probiotics, or allergen-specific immunotherapy, may help manage mild allergies. However, these may not provide the rapid relief Apoquel offers. Consult your vet for the best approach.

Can Apoquel be given alongside flea or tick treatments?

Yes, Apoquel can generally be given with flea and tick preventatives. Ensure to inform your veterinarian about all medications and supplements your dog is taking to avoid potential interactions.

Does Apoquel require a prescription?

Yes, Apoquel is a prescription medication. A veterinarian must evaluate your dog’s condition and provide the appropriate dosage based on their specific needs.

What should I do if my dog accidentally ingests too many Apoquel tablets?

Contact your veterinarian immediately if your dog overdoses on Apoquel. Overdoses may cause symptoms like vomiting, diarrhea, or lethargy, requiring prompt medical attention.

Are there any specific breeds that should avoid using Apoquel?

Apoquel is not breed-specific but may require careful monitoring in breeds prone to certain conditions, such as cancer or immune system disorders. Always discuss your dog’s breed-specific risks with your veterinarian.

Clinical Research: 

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=275a2c51-9679-4f42-b8cc-21b04369a056

https://pubmed.ncbi.nlm.nih.gov/35300697/