{"product_id":"dechra-sporimune-cyclosporine-capsules-usp-modified-100mg","title":"Sporimune (Cyclosporine) USP Modified, 100mg (15 capsules)","description":"\u003cp align=\"center\"\u003e\u003cimg src=\"https:\/\/hardypaw.com\/cdn\/shop\/files\/rx-map.webp\" class=\"img-responsive\" alt=\"RX MAP\" width=\"700\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch2\u003eControls Atopic Dermatitis Symptoms in Dogs Effectively\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSporimune (cyclosporine) USP Modified 100 mg capsules assist in managing atopic dermatitis in dogs by focusing on the immune response that triggers itching and skin inflammation. This therapy, suggested by veterinarians, produces a microemulsion for enhanced absorption, helps with ongoing allergy control, and permits dose tapering following clinical improvement, delivering a steroid-free remedy for chronic allergic skin conditions in dogs.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargets Immune Response: \u003c\/strong\u003eModifies T lymphocyte behaviour and interleukin-2 synthesis to mitigate allergic inflammation, prioritizing lasting solutions over temporary symptom relief.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eControls Chronic Itching: \u003c\/strong\u003eDemonstrated in clinical trials to effectively lower pruritus and the intensity of skin lesions associated with canine atopic dermatitis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSteroid Free Therapy:\u003c\/strong\u003e Provides an alternative to corticosteroids or antihistamines for long-term allergy management in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlexible Dosing Schedule:\u003c\/strong\u003e After initial treatment, dosing frequency can often be reduced to every other day or twice weekly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReliable Absorption:\u003c\/strong\u003e Modified microemulsion formulation enhances bioavailability and consistent drug absorption when administered orally.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eCyclosporine (USP Modified) 100 mg per capsule\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended-Dosage Chart\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 52.7181%; height: 47px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 53.1015%; height: 35.5966px;\" width=\"225\"\u003e\n\u003cp\u003e\u003cstrong\u003eDog Body Weight\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 46.6213%; height: 35.5966px;\" width=\"198\"\u003e\n\u003cp\u003e\u003cstrong\u003eDose (5 mg\/kg)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 53.1015%; height: 35.5966px;\" width=\"225\"\u003e\n\u003cp\u003e33.1 – 64 lbs (15 – 28.9 kg)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 46.6213%; height: 35.5966px;\" width=\"198\"\u003e\n\u003cp\u003e100 mg capsule\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 53.1015%; height: 35.5966px;\" width=\"225\"\u003e\n\u003cp\u003e64.1 – 79 lbs (29 – 35.9 kg)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 46.6213%; height: 35.5966px;\" width=\"198\"\u003e\n\u003cp\u003e100 mg + 50 mg capsule\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 53.1015%; height: 35.5966px;\" width=\"225\"\u003e\n\u003cp\u003e79.1 – 121 lbs (36 – 55.9 kg)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 46.6213%; height: 35.5966px;\" width=\"198\"\u003e\n\u003cp\u003e2 × 100 mg capsules\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003e\u003cstrong\u003eDosage \u0026amp; Administration Instructions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary Prescription Required:\u003c\/strong\u003e This medication is restricted to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInitial Daily Dose:\u003c\/strong\u003e Administer 5 mg\/kg once daily for 30 days before considering a gradual reduction in dosing frequency.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaintenance Adjustment:\u003c\/strong\u003e After improvement, dosing frequency may be reduced to every other day or twice weekly to maintain response.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMeal Timing: \u003c\/strong\u003eOffer capsules at least an hour before or two hours post-feeding for maximum absorption.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMissed Dose: \u003c\/strong\u003eIf a dose is forgotten, give it as soon as possible, ensuring you do not go over the once-daily dosage.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Information\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAge Restrictions:\u003c\/strong\u003e Safety and effectiveness are not established in \u003ca href=\"\/en-ca\/blogs\/news\/everything-need-know-raise-healthy-happy-dog\" title=\"Everything you need to know to raise a healthy happy dog\" aria-label=\"Everything you need to know to raise a healthy happy dog\"\u003edogs younger\u003c\/a\u003e than six months or weighing under four pounds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Safety:\u003c\/strong\u003e Not recommended for breeding, pregnant, or lactating dogs due to lack of safety data.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune Suppression:\u003c\/strong\u003e Immunosuppressive action may increase susceptibility to infections or exacerbate preexisting neoplastic conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiabetes Caution:\u003c\/strong\u003e May elevate blood glucose levels, so careful monitoring is advised in dogs with diabetes mellitus.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e Use cautiously with medications affecting cytochrome P450 enzymes, including azole antifungals like ketoconazole.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Symptoms:\u003c\/strong\u003e The side effects most often reported during treatment include vomiting and diarrhea.\u003c\/li\u003e\n\u003cli\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGum Swelling: \u003c\/strong\u003eGingival hyperplasia can happen, usually getting better after lowering the dose or changing the treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy \u0026amp; Appetite Loss:\u003c\/strong\u003e Some dogs may experience reduced appetite, lethargy, or decreased activity during therapy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfection Risk:\u003c\/strong\u003e Increased susceptibility to infections such as otitis externa or urinary tract infections may develop.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurological Events:\u003c\/strong\u003e Rare cases of tremors or seizures have been reported in dogs receiving cyclosporine therapy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Store capsules at a stable temperature of 68°F to 77°F (20°C to 25°C).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOriginal Packaging:\u003c\/strong\u003e Keep medication in the original unit dose container to maintain stability and protection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChild Safety:\u003c\/strong\u003e Keep out of reach of children and other pets to prevent accidental ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eShipping \u0026amp; Return\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/en-ca\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ca\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e \u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eQ1: What is Sporimune used for in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Sporimune is used to manage atopic dermatitis in dogs by lowering the immune responses that cause itching and skin inflammation. It aids in decreasing itching and skin problems linked to allergic dermatitis and is meant for dogs that weigh a minimum of 4 pounds, under the care of a veterinarian.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ2: How long does Sporimune take to work in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Clinical research indicates that itching and skin severity scores improve within roughly four weeks of daily treatment. After the initial improvement, veterinarians might decrease the frequency of dosing to sustain the results, though the response time can differ based on the specific dog's condition and severity.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ3: How should Sporimune be given to dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Sporimune capsules should be administered orally at least one hour before or two hours after feeding. Capsules must not be opened or broken. The usual initial dose is 5 mg for each kilogram taken once a day for 30 days, then the frequency can be adjusted according to the clinical response.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ4: Is Sporimune a steroid or an antihistamine?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Sporimune is neither a corticosteroid nor an antihistamine. It contains cyclosporine, an immunosuppressive agent that works by inhibiting T lymphocyte activation and interleukin-2 production, targeting the underlying immune cause of allergic dermatitis rather than only relieving symptoms temporarily.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ5: What are the most common side effects of Sporimune?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The most commonly reported side effects include vomiting and diarrhea, especially during the early treatment period. Other possible reactions include lethargy, decreased appetite, gum enlargement, and infections. Many side effects improve with continued therapy or dose adjustments under veterinary guidance.\u003c\/p\u003e","brand":"Dechra","offers":[{"title":"Default Title","offer_id":43864706023585,"sku":"SPOR100-15","price":142.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/sporimune-cyclosporine-usp-modified-100mg-15-capsules-dog-allergy-376.png?v=1777918071","url":"https:\/\/hardypaw.com\/en-ca\/products\/dechra-sporimune-cyclosporine-capsules-usp-modified-100mg","provider":"HardyPaw","version":"1.0","type":"link"}