{"product_id":"felycin-ca1-sirolimus-delayed-release-tablets-cats","title":"Felycin-CA1 (Sirolimus Delayed-Release) Tablets for Cats, 12 tablets","description":"\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eOnce-Weekly Cardiac Support for Cats\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eProduct Description\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eFight back with Felycin-CA1 (\u003ca href=\"\/en-ca\/products\/felycin-ca1-sirolimus-delayed-release-tablets-cats\" title=\"Felycin-ca1 sirolimus delayed-release tablets for cats\" aria-label=\"Felycin-ca1 sirolimus delayed-release tablets for cats\"\u003esirolimus delayed-release tablets\u003c\/a\u003e). The first FDA conditionally approved, once-weekly drug for the management of ventricular hypertrophy in cats with subclinical hypertrophic cardiomyopathy, or HCM. A silent killer of cats that affects one of every seven cats. Finally, screening cats to diagnose this disease early will help put an end to owners feeling powerless. The solution of Felycin-CA1 is the only disease-modifying drug for cats with HCM.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eBenefits\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\u003cspan\u003eProven safe with a reasonable expectation of effectiveness; Felycin-CA1 is the first and only disease-modifying drug for cats with HCM.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\u003cspan\u003eFelycin-CA1 is administered once-weekly and is formulated specifically for cats in small tablet sizes for easy administration.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\u003cspan\u003eFelycin-CA1 is an affordable treatment option for cat owners that may prevent and delay progressive LV hypertrophy that affects 1 in 7 cats.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\u003cspan\u003eA conditionally approved drug is a designated by the FDA that is given when a product has been proven safe with a reasonable expectation of effectiveness based on the studies performed. This designation is often used by the FDA when there is an established need in disease states for which there is no other treatment option while the drug manufacturer continues to perform all required testing in larger cat populations.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\u003cspan\u003eFelycin-CA1 is a prescription drug to be prescribed by a licensed veterinarian after a confirmed HCM diagnosis. Felycin-CA1 should not be used in cats with diabetes mellitus. Do not administer in cats with pre-existing liver disease.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eVariants\u003c\/span\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\u003cspan\u003e0.4 mg tablet strength\u003c\/span\u003e\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\u003cspan\u003e1.2 mg tablet strength\u003c\/span\u003e\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\u003cspan\u003e2.4 mg tablet strength\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 dir=\"ltr\"\u003e\u003cspan\u003eActive Ingredient\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSirolimus (rapamycin)\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eHow to Use\u003c\/span\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cspan\u003eDirections\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eFelycin-CA1 (sirolimus delayed-release tablets) should be given orally daily as directed by your veterinarian with or without food.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4 dir=\"ltr\"\u003e\u003cspan\u003eRecommended Dosage Chart\u003c\/span\u003e\u003c\/h4\u003e\n\u003cdiv align=\"left\" dir=\"ltr\"\u003e\n\u003ctable\u003e\n\u003ccolgroup\u003e \u003ccol width=\"135\"\u003e \u003ccol width=\"60\"\u003e \u003ccol width=\"60\"\u003e \u003ccol width=\"60\"\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBody Weight (kg)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e0.4 mg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e1.2 mg\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e2.4 mg\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e2.5 – 3.2\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e2\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e0\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e0\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e3.3 – 4.8\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e0\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e0\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e4.9 – 6.4\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e0\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e6.5 – 9.6\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e0\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e\u0026gt; 9.6\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e0\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eDisclaimer: \u003c\/span\u003e\u003cspan\u003eThis dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4 dir=\"ltr\"\u003e\u003cspan\u003eDosage and Administration Instructions\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eAdminister FELYCIN®-CA1 at a target dosage of 0.3 mg\/kg (0.14 mg\/lb) orally once weekly. Approximate pounds (lbs) equivalents are provided for convenience only. Always consult your veterinarian for the most accurate dosing, and to ensure proper use of this medication. FELYCIN®-CA1 should be swallowed whole and not chewed. Do not split or crush tablets. FELYCIN®-CA1 should be administered in conjunction with a meal. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eAdditional Information\u003c\/span\u003e\u003c\/h3\u003e\n\u003ch4 dir=\"ltr\"\u003e\u003cspan\u003ePrecautions\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cstrong\u003eNot for diabetic cats\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e: \u003c\/strong\u003eDo not use in cats with diabetes mellitus, and discontinue immediately if diabetes is diagnosed.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cstrong\u003eAvoid liver disease cases\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e: \u003c\/strong\u003eDo not administer to cats with existing liver disease due to increased metabolic risk and enzyme elevation.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cstrong\u003eMonitor liver enzymes\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e: \u003c\/strong\u003eCheck ALT and AST before treatment and repeat testing one to two months after starting therapy.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cstrong\u003eDiscontinue for high enzymes\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e: \u003c\/strong\u003eStop treatment if ALT or AST exceeds two times the upper limit of normal values.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cstrong\u003eUse caution with drug interactions\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e: \u003c\/strong\u003eAvoid concurrent use with CYP3A4 or P-glycoprotein inhibitors like azoles or cyclosporine.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cstrong\u003eAvoid use in intact animals\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e: \u003c\/strong\u003eEffectiveness has not been evaluated in sexually intact cats and should not be used in breeding animals.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cstrong\u003eUse caution with MDR1 mutation\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e: \u003c\/strong\u003eCats with MDR1 gene variants may have altered drug transport requiring extra veterinary oversight.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 dir=\"ltr\"\u003e\u003cspan\u003ePossible Side Effects\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eThe most frequently observed adverse reactions in cats treated with FELYCIN®-CA1 were cardiovascular in nature, relating to the progression of HCM, and included arrhythmia, congestive heart failure, syncope, and pericardial effusion. Other adverse reactions observed were lethargy, vomiting, diarrhea, and inappetence.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4 dir=\"ltr\"\u003e\u003cspan\u003eStorage Information\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eStore at 68-77°F (20-25°C). Excursions permitted between 59-86°F (15-30°C). \u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eShipping \u0026amp; Return\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWe offer ground, express, priority, and international delivery; see our \u003c\/span\u003e\u003ca href=\"\/en-ca\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003e\u003cspan\u003eshipping policy\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e for details.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eFor return instructions or product concerns, please refer to our detailed \u003c\/span\u003e\u003ca href=\"\/en-ca\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003e\u003cspan\u003erefund policy\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eFrequently Asked Questions\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ1: Why is Felycin-CA1 considered a breakthrough treatment for cats with HCM?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAns:\u003c\/span\u003e\u003cspan\u003e Felycin-CA1 is the first and only disease-modifying therapy proven safe with a reasonable expectation of effectiveness for managing feline hypertrophic cardiomyopathy. It offers veterinarians a new way to address the underlying condition rather than only treating symptoms.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ2: How often do I need to give Felycin-CA1 to my cat?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAns:\u003c\/span\u003e\u003cspan\u003e Felycin-CA1 is given once weekly and is made specifically for cats using small tablet sizes that make dosing easier for pet owners. This formulation supports simple and stress-free administration during long-term heart care.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ3: How can Felycin-CA1 help protect my cat’s heart long term?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAns:\u003c\/span\u003e\u003cspan\u003e Felycin-CA1 is an affordable treatment option that may help prevent and delay progressive left ventricular hypertrophy, a condition affecting roughly one in seven cats. Its once-weekly dosing supports early intervention for \u003ca href=\"\/en-ca\/collections\/cat-health-care\" title=\"Cat health care: best feline health care products for wellness | hardypaw\" aria-label=\"Cat health care: best feline health care products for wellness | hardypaw\"\u003ebetter long-term cardiac health\u003c\/a\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ4: What does it mean that Felycin-CA1 is conditionally approved by the FDA?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAns:\u003c\/span\u003e\u003cspan\u003e Conditional approval means the FDA has determined the medication is proven safe with a reasonable expectation of effectiveness. This designation is used when no other treatment exists, allowing access while the manufacturer completes required studies in larger cat populations.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ5: When can my cat be prescribed Felycin-CA1?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAns:\u003c\/span\u003e\u003cspan\u003e Felycin-CA1 can only be prescribed by a licensed veterinarian after confirming hypertrophic cardiomyopathy. It must not be used in cats with diabetes mellitus or those with pre-existing liver disease, as these conditions increase risk during treatment.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ6: How should I give Felycin-CA1 to my cat?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAns:\u003c\/span\u003e\u003cspan\u003e Felycin-CA1 should be given orally exactly as instructed by your veterinarian, with or without food. Always follow the dosing schedule provided by your vet to ensure proper use and consistent therapeutic benefit for your cat.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ7: What is Felycin-CA1 used for in cats?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAns:\u003c\/span\u003e\u003cspan\u003e Felycin-CA1 is used to manage \u003ca href=\"\/en-ca\/collections\/cat-medications\" title=\"Cat medications: flea \u0026amp; tick, nasal, antibiotics \u0026amp; more! | hardypaw\" aria-label=\"Cat medications: flea \u0026amp; tick, nasal, antibiotics \u0026amp; more! | hardypaw\"\u003eventricular hypertrophy\u003c\/a\u003e in cats diagnosed with subclinical hypertrophic cardiomyopathy. It modifies disease progression by reducing heart muscle thickening when used once weekly as directed.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ8: How long does my cat need to stay on Felycin-CA1?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAns:\u003c\/span\u003e\u003cspan\u003e Cats with subclinical HCM typically remain on Felycin-CA1 long term because the treatment works to slow progressive cardiac thickening over time. Continued weekly dosing is recommended unless a veterinarian advises changes.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ9: Can Felycin-CA1 be given with other medications?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAns:\u003c\/span\u003e\u003cspan\u003e Certain medications like azoles, amiodarone, cyclosporine, and calcium channel blockers may affect sirolimus metabolism. Veterinarians must evaluate drug interactions before combining therapies to ensure safe use.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ10: What signs should I watch for while my cat is taking Felycin-CA1?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAns:\u003c\/span\u003e\u003cspan\u003e Cats should be monitored for vomiting, diarrhea, reduced appetite, lethargy, arrhythmias, or breathing concerns. Any sudden collapse or worsening clinical signs requires immediate veterinary evaluation during therapy.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003e\u003cspan\u003eQ11: How soon can improvements be seen with Felycin-CA1?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003eAns: Clinical studies show reductions in maximal left ventricular wall thickness after 180 days of weekly dosing. Regular veterinary checkups and echocardiograms help assess progress during treatment.\u003c\/p\u003e","brand":"PRN Pharmacal","offers":[{"title":"0.4-mg","offer_id":45142809608353,"sku":"30091693","price":77.0,"currency_code":"CAD","in_stock":true},{"title":"1.2-mg","offer_id":45142809641121,"sku":"30091793","price":214.0,"currency_code":"CAD","in_stock":true},{"title":"2.4-mg","offer_id":45142809673889,"sku":"30091893","price":357.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/felycin-ca1-sirolimus-delayed-release-tablets-for-cats-12-0-4-mg-454.png?v=1777665247","url":"https:\/\/hardypaw.com\/en-ca\/products\/felycin-ca1-sirolimus-delayed-release-tablets-cats","provider":"HardyPaw","version":"1.0","type":"link"}