Leflunomide 20mg Tablets (Manufacturer may vary)

Leflunomide Tablets for Autoimmune Disorders in Pets

Leflunomide 20mg Tablets are a trusted immunosuppressant medication prescribed to manage and treat immune-mediated disorders in pets, particularly dogs and cats. It is highly effective for conditions such as immune-mediated hemolytic anemia (IMHA), polyarthritis, or rheumatoid arthritis. In cases where pets show adverse reactions or limited response to other treatments, Leflunomide serves as a vital alternative or supplementary therapy.

All prescription items are Non-Refundable and Non-Returnable.

Also Available in : Leflunomide Tablets 10mg 

What Are the Benefits of Leflunomide for Pets?

• Manages Chronic Inflammatory Conditions: Alleviates symptoms of rheumatoid arthritis and polyarthritis.
• Treats Autoimmune Disorders: Effective for immune-mediated hemolytic anemia (IMHA) in dogs.
• Supports Non-Responsive Cases: Works well when traditional immunosuppressants fail.
• Customizable for Cats and Dogs: Suitable for combination therapy for complex cases.

How to Administer Leflunomide Tablets?

Dosage and Administration:

• Always consult your veterinarian for the exact dosage tailored to your pet’s weight, condition, and specific needs.
• Administer the tablet orally with or without food, as directed.

Are There Any Potential Side Effects of Leflunomide ?

While Leflunomide is generally well-tolerated, some pets may experience:

• Digestive upset, including diarrhea or vomiting.
• Reduced appetite.
• Lethargy or fatigue.
• Rarely, liver toxicity or bone marrow suppression (monitor liver enzymes with your vet regularly).

If your pet exhibits unusual symptoms, contact your veterinarian promptly.

What Are the Ingredients in Leflunomide Tablets?

Active Ingredient: Leflunomide 20mg.
Inactive Ingredients: Specific excipients (consult product label for details).

How Does Leflunomide Work?

Leflunomide metabolizes into teriflunomide, its active form, which targets the immune system's overactivity. This compound inhibits the synthesis of DNA and RNA in replicating lymphocytes, effectively reducing inflammation and tissue damage caused by an overproduction of immune cells.

Important Warnings and Precautions

• Do not use in pregnant or lactating animals due to potential risks.
• Inform your vet about any existing health conditions or ongoing medications to avoid drug interactions.
• Keep out of reach of children and other animals.

How to Store Leflunomide Tablets?

• Store at room temperature (68-77°F) in a dry, cool place.
• Protect from direct sunlight and moisture.

Shipping & Returns 

Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

FAQs - Leflunomide Tablets for Dogs and Cats

What is Leflunomide Tablets used for?

Leflunomide Tablets are used to treat autoimmune disorders in pets, including immune-mediated hemolytic anemia (IMHA), polyarthritis, and rheumatoid arthritis. It is also an alternative or additional therapy for pets unresponsive to other immunosuppressants.

How does Leflunomide differ from other immunosuppressants?

Leflunomide specifically inhibits DNA and RNA synthesis in lymphocytes, targeting the immune cells responsible for inflammation without the broader side effects often seen with steroids or general immunosuppressants.

Can Leflunomide be used in pets with liver conditions?

Leflunomide should be used cautiously in pets with pre-existing liver conditions due to the risk of hepatotoxicity. Regular liver enzyme monitoring by your veterinarian is essential to ensure safe use.

Is Leflunomide safe for long-term use in pets?

Yes, Leflunomide is generally safe for long-term use when prescribed by a veterinarian. Regular check-ups, including blood tests, are recommended to monitor for any potential side effects or complications.

Can Leflunomide be used for cats with autoimmune diseases?

Yes, Leflunomide is effective for treating autoimmune conditions in cats, such as polyarthritis and certain immune-mediated disorders. The dosage is carefully adjusted based on the cat’s weight and health condition.

How do I know if my pet is responding well to Leflunomide?

Signs of improvement may include reduced joint swelling, less stiffness, increased mobility, and a decrease in other symptoms like lethargy or fever. Regular veterinary evaluations are necessary to assess your pet’s response to the medication.

Are there natural alternatives to Leflunomide for pets?

Some natural supplements like omega-3 fatty acids, turmeric, and glucosamine may help with inflammation but are not substitutes for Leflunomide in managing severe autoimmune conditions. Always consult your veterinarian before introducing alternatives.

What should I do if my pet misses a dose of Leflunomide?

If a dose is missed, administer it as soon as possible unless it is close to the next scheduled dose. Do not double the dose to compensate for the missed one, and consult your veterinarian for further guidance.

Can Leflunomide cause weight changes in pets?

While not common, some pets may experience weight changes due to reduced appetite or metabolic effects of the medication. Monitor your pet’s weight regularly and inform your veterinarian of significant changes.

Is Leflunomide safe for pregnant pets?

Leflunomide is not safe for pregnant pets as it may cause harm to developing fetuses. Inform your veterinarian if your pet is pregnant or may become pregnant during treatment.

Clinical Researches:

• "Efficacy of leflunomide for treatment of immune-mediated polyarthritis in dogs: 14 cases (2006–2008)"
  This study assessed leflunomide's effectiveness in treating dogs with immune-mediated polyarthritis, providing insights into appropriate dosing and observed adverse effects. AVMA Journals

• "Leflunomide with prednisone or nonsteroidal anti-inflammatory drug therapy is safe and tolerated for long-term treatment of immune-mediated polyarthritis in 27 dogs"
  This research evaluated the long-term safety and tolerance of leflunomide combined with either prednisone or NSAIDs in dogs, highlighting its role in managing immune-mediated polyarthritis.  AVMA Journals