Legend (Hyaluronate Sodium) Multi Dose Injectable Solution (20 ml)

Legend (Hyaluronate Sodium)Multi Dose Injectable Solution (20 ml)

EGEND Injectable Solution is indicated in the treatment of joint dysfunction of the carpus or fetlock in horses due to non-infectious synovitis associated with equine osteoarthritis. Equine osteoarthritis can happen in any age and any discipline due to everyday wear and tear. It is permanent and can lead to early retirement and quality-of-life issues in horses.

The active ingredient in LEGEND, hyaluronic acid (HA), decreases the presence of inflammatory mediators in the joint, improves synovial fluid quality, and reduces the degree of lameness. These improvements are seen whether LEGEND is administered by intravenous (I.V.) or intra-articular (I.A.) injection. LEGEND hyaluronate sodium injectable is sterile, pyrogen-free and FDA-approved.

Benefits 

• Safe and efficacious

• 90% of cases treated I.V. judged to have excellent to good overall clinical improvement¹

• 96% of horses treated intra-articularly were judged to have excellent to good overall clinical improvement¹

• Improvement can be seen after one dose

• Provides multi-modal approach against the cycle of inflammation and lameness

• Stimulates endogenous hyaluronic acid production²

• Creates a physical barrier to exclude inflammatory mediators³

• Decreases the presence of inflammatory mediators⁴

Recommended Dosage

Use as directed by your veterinarian. 

LEGEND Multi Dose (20 mL) and LEGEND 4 mL (40 mg) can be injected intravenously only at a dosage of 4 mL. Intravenous treatment may be repeated at weekly intervals for a total of 3 treatments. 

Safety Information

The safety of LEGEND 20 mL has not been evaluated in breeding stallions or in breeding, pregnant or lactating mares. The following adverse reactions have been reported following intravenous use of LEGEND 20 mL Injectable Solution: occasional depression, lethargy, and fever. Not for intra-articular use. The intra-articular safety of hyaluronate sodium with benzyl alcohol has not been evaluated.

The following adverse reactions have been reported following use of LEGEND Injectable Solution: Following intravenous use: occasional depression, lethargy, and fever. Following intra-articular (LEGEND Injectable Solution — 2 mL only) use: lameness, joint effusion, joint or injection site swelling and joint pain.

Storage Instructions

Store at or below 77° F (25° C). Brief excursions to 104° F (40° C) are permitted.

All prescription items are Non-Refundable and Non-Returnable.