Thyro-Tabs (Levothyroxine Sodium) for Dogs, 1.0 mg

Highest-Strength Levothyroxine Tablet for Large Hypothyroid Dogs

Product Description

Thyro-Tabs Canine (Levothyroxine Sodium Tablets, USP) 1.0 mg is an FDA-approved prescription thyroid hormone replacement for dogs, supplied as tan scored oval tablets in bottles of 120 or 1,000. Each tablet delivers 1.0 mg levothyroxine sodium, the highest single-tablet strength in the nine-strength Thyro-Tabs Canine line. It provides synthetic T4 that is chemically identical to the hormone a healthy canine thyroid produces naturally, and is indicated for replacement therapy of diminished thyroid function in dogs. Best suited to large and giant-breed dogs, or any dog whose serum TT4 monitoring confirms a need for maximum daily T4 supplementation.

Benefits

• Maximum Single-Tablet Strength: At 1.0 mg, this is the highest dose available in a single Thyro-Tabs Canine tablet, removing the need to give multiple tablets to large dogs.
• Ideal for Large and Giant Breeds: Dogs with greater body mass require proportionally higher T4 supplementation; the 1.0 mg strength is purpose-matched to these high-dose needs.
• High Clinical Success Rate: A US controlled field study confirmed 75.6% of evaluable dogs achieved treatment success with TT4, fT4, and TSH values normalized by Day 182.
• Resolves Hypothyroid Clinical Signs: Weight gain, dullness, hair loss, skin changes, and elevated blood cholesterol were all areas that showed measurable improvement throughout the field study.
• Once or Twice Daily Flexibility: The full 1.0 mg daily dose can be given as a single tablet every 24 hours or divided equally into two administrations every 12 hours as the vet directs.
• Scored Tablet for Precision: The tan oval tablet is scored, giving the vet the option to prescribe a half-tablet dose of 0.5 mg as an interim step during dose titration if needed.

Ingredients

Active Ingredients

Levothyroxine Sodium (Anhydrous): 1.0 mg per tablet

How to Use

Dosage and Administration Instructions

• Prescription Required: Federal (USA) law restricts Thyro-Tabs Canine to use by or on the order of a licensed veterinarian only.
• Weight-Based Starting Dose: Begin at 0.1 mg per 10 lbs (0.022 mg/kg) of body weight once daily every 24 hours, or split into two equal doses every 12 hours.
• Peak-Level Sampling Window: Draw the monitoring blood sample 4 to 6 hours after tablet administration to reflect the most accurate peak serum TT4 concentration.
• Regular Recheck Schedule: Monitor TT4 levels and clinical signs every 4 to 8 weeks until a stable maintenance dose is confirmed by both bloodwork and symptom resolution.
• Unwavering Food Routine: Always give the tablet under the same food conditions every day; any change between fed and fasted administration disrupts absorption consistency.
• Do Not Combine Strengths Without Guidance: If more than one tablet size is needed to reach the prescribed dose, confirm the combination with the vet before administering multiple tablets.
• Indefinite Daily Treatment: Most dogs with hypothyroidism require lifelong levothyroxine supplementation; build the tablet into the dog's permanent daily health routine.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Thyrotoxicosis Contraindicated: Do not give Thyro-Tabs to any dog where elevated thyroid hormone has already been identified or where thyrotoxicosis is confirmed.
• Adrenal Insufficiency Must Be Corrected: Address any existing adrenal insufficiency fully before starting thyroid replacement to prevent triggering a serious hormonal imbalance.
• Extra Care with Cardiac Dogs: Large dogs with heart conditions starting on 1.0 mg levothyroxine need especially close cardiac monitoring as metabolic demands rise during treatment.
• Cardiac Drug Dose May Need Review: Once thyroid replacement begins, any concurrent heart medication dose may require veterinary reassessment and possible adjustment.
• Breeding and Reproductive Dogs: The safety of Thyro-Tabs Canine has not been established in breeding, pregnant, or lactating dogs; seek veterinary input before use in these animals.
• Multiple Drug Interactions Possible: Corticosteroids, anticonvulsants, calcium supplements, and antacids can each alter levothyroxine uptake; share all current medications with the vet first.
• Secure from All Animals and Children: Keep the bottle locked away from all household pets and children to prevent any accidental ingestion of these high-dose thyroid tablets.

Possible Side Effects

• Pruritus: Itching is the most commonly reported adverse reaction in Thyro-Tabs Canine post-approval adverse drug experience data across all strength levels.
• Serum T4 Imbalances: Both high and low TT4 readings are frequently submitted as post-approval events; scheduled post-dose bloodwork is the most reliable way to catch these.
• Polydipsia and Polyuria: Noticeable increases in drinking and urination have appeared in post-approval reports and may indicate the dose needs downward adjustment.
• Vomiting and Appetite Loss: Gastrointestinal signs including vomiting and anorexia have been documented in both the controlled field study and through post-approval submissions.
• Elevated Liver Enzymes: Raised ALP, ALT, or AST values were observed in three field study dogs; two of these normalized spontaneously without any change to the treatment plan.
• Skin and Coat Reactions: Post-approval experience includes reports of alopecia, seborrhea, dermatitis, and rare hypersensitivity reactions such as hives or facial swelling.

Storage Information

• Store at Controlled Room Temperature: Keep at 20-25°C (68-77°F); brief excursions between 15-30°C (59-86°F) are permitted without affecting the potency or stability of the tablets.
• Protect from Light and Humidity: Keep the bottle sealed tightly and away from direct sunlight, excess moisture, and heat sources to preserve levothyroxine sodium quality throughout the shelf life.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Thyro-Tabs Canine 1.0 mg tan tablet used for in dogs?

Ans: Thyro-Tabs Canine 1.0 mg is the highest-strength FDA-approved prescription levothyroxine tablet for dogs with hypothyroidism. It provides the maximum single-tablet dose of synthetic T4, restoring thyroid hormone levels in large and giant-breed dogs or those whose serum monitoring confirms the greatest daily supplementation need.

Q2: Why might a large dog need the 1.0 mg Thyro-Tabs strength rather than a lower dose?

Ans: Levothyroxine dosing is weight-based; larger dogs need proportionally more T4 each day to restore normal thyroid hormone levels. A dog weighing 100 lbs would require 1.0 mg daily based on the 0.1 mg per 10 lbs starting calculation, making the 1.0 mg tan tablet the most practical single-tablet choice for that size.

Q3: How often should a large dog on Thyro-Tabs 1.0 mg levothyroxine have blood tests?

Ans: TT4 levels should be checked every 4 to 8 weeks during the initial phase, with blood drawn 4 to 6 hours after the dose for the most accurate peak reading. Once the dose is confirmed stable through consistent monitoring results, the vet will typically extend the interval to every 3 to 6 months for ongoing maintenance.

Q4: Can the Thyro-Tabs 1.0 mg tan tablet be combined with other Thyro-Tabs strengths?

Ans: In some cases a vet may prescribe a combination of tablet strengths to reach a precise dose that sits between standard options. Any multi-tablet combination should only be used exactly as prescribed; never adjust the combination or add extra tablets without first consulting the veterinarian overseeing the dog's thyroid management.

Q5: Is Thyro-Tabs 1.0 mg the same as human levothyroxine tablets for dogs?

Ans: Thyro-Tabs Canine contains the same active ingredient as human levothyroxine — levothyroxine sodium USP — and is manufactured under the same FDA standards in the same facilities. However, it carries a specific canine FDA approval (NADA 141-448), while human products are approved separately and should not be interchanged with the canine product without veterinary direction.

Clinical Research

https://www.msdvetmanual.com/endocrine-system/the-thyroid-gland/hypothyroidism-in-animals

https://www.petmd.com/dog/conditions/endocrine/c_dg_hypothyroidism

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=38005382-289a-4293-b58e-b1cda8bc228