{"product_id":"trifexis-flea-worm-chewable-tablets-for-small-dogs-orange-box","title":"Trifexis Chewable Tablets for Dogs 10.1-20 lbs (Spinosad + Milbemycin Oxime)","description":"\u003ch2\u003e5-in-1 Monthly Flea, Heartworm \u0026amp; Intestinal Parasite Protection for Small-to-Medium Dogs (10.1–20 lbs)\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eTrifexis Chewable Tablets (Orange Box) are a prescription, once-monthly oral treatment for dogs and puppies weighing between 10.1 and 20 pounds. Each beef-flavored tablet combines Spinosad and Milbemycin Oxime to take on five different parasites in a single monthly dose. It kills fleas quickly, blocks heartworm disease, and clears adult hookworm, roundworm, and whipworm infections all at once. Any puppy past the 8-week mark and weighing no less than 5 pounds is ready to start on this product.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eKills Fleas Fast:\u003c\/strong\u003e Spinosad gets to work on fleas within 30 minutes of the tablet being given and reaches complete flea kill effectiveness by the 4-hour mark.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevents Heartworm Disease:\u003c\/strong\u003e Milbemycin Oxime targets the L3 and L4 larval stages of Dirofilaria immitis before they get the chance to develop into adult heartworms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eControls Flea Infestations:\u003c\/strong\u003e Clears out existing flea infestations and stops fresh ones from taking hold; field studies showed flea reductions of 98% to 99.8% over three treatments.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Roundworms:\u003c\/strong\u003e Delivers 90% or greater effectiveness against adult Toxocara canis and Toxascaris leonina roundworm infections in small-to-medium dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Hookworms:\u003c\/strong\u003e Clears adult Ancylostoma caninum infections, a parasite known to cause serious blood loss even in otherwise healthy smaller dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Whipworms:\u003c\/strong\u003e Takes care of adult Trichuris vulpis infections, a level of coverage that a good number of heartworm-only products do not offer.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEasy to Administer:\u003c\/strong\u003e The beef-flavored tablet can be offered by hand, stirred into a meal, or hidden in a treat, making monthly dosing hassle-free for small-to-medium dog owners.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo Drying Time Needed:\u003c\/strong\u003e There is no waiting period after giving this tablet; dogs can be cuddled and played with straight after their monthly dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTrusted by Dog Owners:\u003c\/strong\u003e Close to ten years in use and upward of 272 million doses confirm just how reliable this parasite tablet has proven to be.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients (per tablet, 10.1–20 lb dogs)\u003c\/h4\u003e\n\u003cp\u003eSpinosad 270 mg, Milbemycin Oxime 4.5 mg\u003c\/p\u003e\n\u003ch4\u003eOther Ingredients\u003c\/h4\u003e\n\u003cp\u003eThe beef flavoring in this tablet comes from artificial beef flavoring derived from pork-based proteins and hydrolyzed soy, not from real beef.\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e This FDA-approved tablet can only be sourced through a licensed veterinarian with a valid veterinarian-client-pet relationship in place.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonthly Oral Dose:\u003c\/strong\u003e Give one full chewable tablet by mouth once every month, keeping to roughly the same date each time for uninterrupted year-round coverage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlways Give With Food:\u003c\/strong\u003e This tablet must always be given alongside a meal; administering on an empty stomach may reduce how effectively it works.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow to Offer the Tablet:\u003c\/strong\u003e Hand it over directly, mix it into food, or tuck it inside a treat; it is made to appeal to dogs in this weight range.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWatch After Dosing:\u003c\/strong\u003e Stay with your dog for one hour after the tablet is given; follow up with a fresh full dose straight away if the stomach does not hold it down.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimum Dose:\u003c\/strong\u003e Every tablet in this size delivers at least 13.5 mg\/lb (30 mg\/kg) Spinosad and 0.2 mg\/lb (0.5 mg\/kg) Milbemycin Oxime per monthly dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSeasonal Use:\u003c\/strong\u003e For seasonal use, begin dosing within one month of first mosquito exposure and keep going for at least three months after the last mosquito season ends.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMissed Dose:\u003c\/strong\u003e If the gap between doses stretches past 30 days, give the tablet with a meal right away and pick up the regular monthly schedule from that point.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimum Age and Weight:\u003c\/strong\u003e Dogs that have passed 8 weeks of age and tipped the scale at 5 pounds or above can be given this tablet safely.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any medication for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeartworm Screening First:\u003c\/strong\u003e Every dog should have a heartworm check with their vet before the first dose, since adult heartworm infections already present are not something this product addresses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Adult Heartworms:\u003c\/strong\u003e This product has no action against adult Dirofilaria immitis; dogs that test positive should finish adulticide treatment before starting on this tablet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThree Doses for Full Cover:\u003c\/strong\u003e Completing fewer than three back-to-back monthly doses after the last mosquito exposure may leave gaps in heartworm protection for your dog.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid Use With Ivermectin:\u003c\/strong\u003e Serious reactions have been noted when Spinosad and ivermectin are given together; always let your vet know about every medication your dog is currently receiving.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDogs Only:\u003c\/strong\u003e This product was made solely for dogs and must never be given to cats under any circumstances whatsoever.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Microfilariae Counts:\u003c\/strong\u003e Dogs with elevated circulating microfilariae may show brief, mild reactions such as laboured breathing, drooling, or low energy when milbemycin oxime is given.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Dogs:\u003c\/strong\u003e Check with your vet before giving this product to females intended for breeding; safety in breeding males has not been formally assessed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFleas After Dosing:\u003c\/strong\u003e Any fleas spotted within a month of dosing have hatched from pre-existing pupae in the environment and will be killed before getting the chance to reproduce.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWorms in Stool:\u003c\/strong\u003e Finding intestinal worms in your dog's stool after dosing is completely normal and a clear sign that the product is working as it should.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eVomiting:\u003c\/strong\u003e The most frequently reported reaction, and more likely in puppies under 14 weeks; give a full replacement tablet right away if it occurs within the first hour.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDigestive Upset:\u003c\/strong\u003e Loose stools, a drop in appetite, or heavier-than-normal drooling have been noted in some dogs following administration of this tablet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLow Energy:\u003c\/strong\u003e A noticeable dip in activity and longer sleep periods than usual have been reported in some dogs after receiving their monthly dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin Reactions:\u003c\/strong\u003e Itching, skin reddening, and areas of localised skin inflammation have been seen in a number of dogs after taking this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurological Reactions:\u003c\/strong\u003e Trembling, shaking, unsteady movement, and seizures have been noted post-approval; get your vet on the phone straight away if any of these appear.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSevere Allergic Reaction:\u003c\/strong\u003e Though uncommon, facial swelling, hives, very pale gums, cold limbs, or sudden collapse all need urgent emergency veterinary care without delay.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e A steady indoor spot that holds between 68°F and 77°F (20°C to 25°C) is the right place to keep this product safe and effective.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafe Storage Practice:\u003c\/strong\u003e Store this prescription tablet well out of reach of children and other household animals to prevent any chance of accidental ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ca\/pages\/shipping-policy\" title=\"Shipping policy\" aria-label=\"Shipping policy\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ca\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What parasites does Trifexis (Orange Box) protect small-to-medium dogs against?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Trifexis (Orange Box) covers five parasites in one monthly tablet: it kills fleas, prevents heartworm disease, and treats adult hookworms, roundworms, and whipworms. It handles the most common parasites dogs in this weight range face but does not cover ticks.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does the Orange Box (10.1–20 lbs) differ from the Magenta Box (5–10 lbs)?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The Orange Box contains 270 mg Spinosad and 4.5 mg Milbemycin Oxime per tablet, while the Magenta Box carries 140 mg Spinosad and 2.3 mg Milbemycin Oxime. Both deliver the same five-way protection. Always pick the tablet size that matches your dog's current body weight.\u003c\/p\u003e\n\u003ch3\u003eQ3: My dog vomited shortly after taking Trifexis. What should I do?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Give a complete replacement tablet with food straight away if your dog brings the dose back up within the first hour. To lower the chance of it happening again, always pair the tablet with a full meal. Reach out to your vet if vomiting carries on or seems severe.\u003c\/p\u003e\n\u003ch3\u003eQ4: Can Trifexis be given to a dog in this weight range that already has heartworms?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No. This product does not treat adult heartworms and is not approved for that use. Every dog must be screened before starting. If a dog tests positive, adulticide treatment should be completed first before this tablet is introduced as a monthly preventive.\u003c\/p\u003e\n\u003ch3\u003eQ5: Does Trifexis contain anything that could affect dogs with food sensitivities?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The beef flavoring comes from artificial beef flavoring using pork-based proteins and hydrolyzed soy, not from real beef. Dogs with known soy or pork sensitivities should be assessed by a vet before starting. This product does not contain gluten.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.heartwormsociety.org\/pet-owner-resources\/heartworm-basics\" title=\"Heartworm basics - american heartworm society\" aria-label=\"Visit a webpage about Heartworm basics - american heartworm society\"\u003eAmerican Heartworm Society\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.avma.org\/resources-tools\/pet-owners\/petcare\/external-parasites\" title=\"External parasites | american veterinary medical association\" aria-label=\"Visit a webpage about External parasites | american veterinary medical association\"\u003eAmerican Veterinary Medical Association (AVMA)\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.petsandparasites.org\/dog-owners\/overview\" title=\"Overview | pets \u0026amp; parasites: the pet owner’s parasite resource\" aria-label=\"Visit a webpage about Overview | pets \u0026amp; parasites: the pet owner’s parasite resource\"\u003eCompanion Animal Parasite Council (CAPC)\u003c\/a\u003e\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"1 Chewable Tablet (1 Month Supply)","offer_id":41109086961825,"sku":"CA4333Y07AM-1","price":39.0,"currency_code":"CAD","in_stock":true},{"title":"6 Chewable Tablets (6 Months Supply)","offer_id":41109086994593,"sku":"CA4333Y07AM","price":212.0,"currency_code":"CAD","in_stock":true},{"title":"12 Chewable Tablets (12 Months Supply)","offer_id":44200157380769,"sku":"CA4333Y07AM-PK2","price":468.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/trifexis-chewable-tablets-for-dogs-10-1-20-lbs-spinosad-milbemycin-520.jpg?v=1777908645","url":"https:\/\/hardypaw.com\/en-ca\/products\/trifexis-flea-worm-chewable-tablets-for-small-dogs-orange-box","provider":"HardyPaw","version":"1.0","type":"link"}