{"product_id":"anipryl-tablets","title":"Anipryl (selegiline) Tablets, 30 tablets","description":"\u003cp align=\"center\"\u003e\u003cimg src=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" class=\"img-responsive\" alt=\"RX MAP\" width=\"700\"\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eSupports Cognitive Function and PDH in Dogs\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eAnipryl is a prescription tablet for dogs that is given by mouth to help manage signs of canine cognitive dysfunction and uncomplicated pituitary dependent hyperadrenocorticism. It contains selegiline hydrochloride, which works by increasing dopamine levels in the brain to support normal brain function and behavior. Given once a day, it comes in flexible dose strengths and has been clinically shown to improve both cognitive symptoms and signs related to PDH.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCognitive Support:\u003c\/strong\u003e Helps control disorientation, altered sleep cycles, and loss of housetraining in aging dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePDH Symptom Control:\u003c\/strong\u003e Assists in managing clinical signs of uncomplicated pituitary-dependent hyperadrenocorticism in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDopamine Enhancement:\u003c\/strong\u003e Selectively inhibits MAO B to increase dopamine levels in the central nervous system.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce Daily Dosing:\u003c\/strong\u003e Administered once daily, preferably in the morning, for convenient long-term management.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlexible Strength Options:\u003c\/strong\u003e Available in multiple tablet strengths to allow individualized dosing based on body weight.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eVariants\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e10 mg Tablets\u003cbr\u003e15 mg Tablets\u003cbr\u003e30 mg Tablets\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eComposition Table\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 42.9225%; height: 208px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003eSelegiline Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e2 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003eSelegiline Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e5 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003eSelegiline Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e10 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003eSelegiline Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e15 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003eSelegiline Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e30 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended-Dosage Chart\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 67.6786%; height: 163px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 55.1989px;\"\u003e\n\u003ctd width=\"175\" style=\"width: 30.9609%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eIndication\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"129\" style=\"width: 22.6806%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dosage\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"74\" style=\"width: 13.1404%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eFrequency\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"189\" style=\"width: 32.2209%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eNotes\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 55.1989px;\"\u003e\n\u003ctd width=\"175\" style=\"width: 30.9609%; height: 55.1989px;\"\u003e\n\u003cp\u003eCanine Cognitive Dysfunction Syndrome\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"129\" style=\"width: 22.6806%; height: 55.1989px;\"\u003e\n\u003cp\u003e0.5 to 1.0 mg per kg body weight\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"74\" style=\"width: 13.1404%; height: 55.1989px;\"\u003e\n\u003cp\u003eOnce daily\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"189\" style=\"width: 32.2209%; height: 55.1989px;\"\u003e\n\u003cp\u003ePreferably administered in the morning.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 94.4034px;\"\u003e\n\u003ctd width=\"175\" style=\"width: 30.9609%; height: 94.4034px;\"\u003e\n\u003cp\u003ePituitary Dependent Hyperadrenocorticism\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"129\" style=\"width: 22.6806%; height: 94.4034px;\"\u003e\n\u003cp\u003e1.0 mg per kg body weight\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"74\" style=\"width: 13.1404%; height: 94.4034px;\"\u003e\n\u003cp\u003eOnce daily\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"189\" style=\"width: 32.2209%; height: 94.4034px;\"\u003e\n\u003cp\u003eMay increase to maximum 2.0 mg per kg if no improvement after 2 months.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003e\u003cstrong\u003eDosage \u0026amp; Administration Instructions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e This medication is restricted to use by or on the order of a licensed veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMorning Administration:\u003c\/strong\u003e Administer once daily, preferably in the morning, to support recommended therapeutic use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustment:\u003c\/strong\u003e Adjust dosage based on individual response and tolerance, under veterinary supervision.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePDH Reassessment:\u003c\/strong\u003e If no improvement after dose increase, reevaluate and consider alternative therapy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Information\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBehavioral Use Limitation:\u003c\/strong\u003e Not recommended for the treatment of other behavior problems, such as aggression.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e Avoid concurrent use with SSRIs, tricyclic antidepressants, or other antidepressants.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFluoxetine Washout:\u003c\/strong\u003e Allow at least five weeks after discontinuing fluoxetine before starting Anipryl.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePDH Confirmation:\u003c\/strong\u003e Confirm pituitary-dependent hyperadrenocorticism diagnosis before initiating therapy for that condition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Safety:\u003c\/strong\u003e Safety has not been determined in breeding, pregnant, or lactating dogs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Signs:\u003c\/strong\u003e Vomiting and diarrhea were commonly reported during clinical field trials.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRestlessness Behavior:\u003c\/strong\u003e Hyperactivity, irritability, and restlessness were observed in treated dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAppetite Changes:\u003c\/strong\u003e Anorexia and weight loss have been reported in some dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurologic Effects:\u003c\/strong\u003e Ataxia, disorientation, incoordination, and seizure-like activity were reported.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy Weakness:\u003c\/strong\u003e Lethargy and generalized weakness occurred in some treated dogs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature:\u003c\/strong\u003e Store at controlled room temperature between 20° to 25° Celsius.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOriginal Packaging:\u003c\/strong\u003e Keep tablets in original blister packaging until administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChild Safety:\u003c\/strong\u003e Keep out of reach of children and not for human use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eShipping \u0026amp; Return\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"https:\/\/hardypaw.com\/pages\/shipping-policies\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"https:\/\/hardypaw.com\/policies\/refund-policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eQ1: What is Anipryl used for in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Anipryl is prescribed to manage the symptoms linked to canine cognitive dysfunction and uncomplicated pituitary dependent hyperadrenocorticism. It increases dopamine activity in the brain, which can help reduce behavior changes and hormone related issues seen in affected dogs.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ2: How long does Anipryl take to show results?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e In clinical trials for cognitive dysfunction, improvement was observed after four weeks of treatment, with some dogs continuing to improve up to three months. For pituitary-dependent hyperadrenocorticism, many responding dogs showed improvement within one to two months of therapy initiation.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ3: What is the recommended dosage of Anipryl for dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e For canine cognitive dysfunction, the recommended dosage is 0.5 to 1.0 mg per kg once daily. For pituitary-dependent hyperadrenocorticism, the recommended dosage is 1.0 mg per kg once daily, which may be increased to 2.0 mg per kg if needed.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ4: Can Anipryl be given with other antidepressant medications?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Anipryl should not be used together with selective serotonin reuptake inhibitors, tricyclic antidepressants, or other antidepressant medications. After stopping Anipryl, wait at least 14 days before starting any of these drugs. If fluoxetine has been used, a longer waiting period of five weeks is required before beginning Anipryl.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ5: What are the common side effects of Anipryl in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e In clinical trials, the most commonly reported side effects included vomiting, diarrhea, increased activity, loss of appetite, tiredness, and nervous system changes such as unsteady movement or confusion. Most of these reactions were mild, but a small number of dogs needed a dose adjustment or had to stop the medication.\u003c\/p\u003e","brand":"Zoetis","offers":[{"title":"10-mg","offer_id":45026758754465,"sku":"10000282","price":89.0,"currency_code":"GBP","in_stock":true},{"title":"15-mg","offer_id":45026755608737,"sku":"10000283","price":94.0,"currency_code":"GBP","in_stock":true},{"title":"30-mg","offer_id":45026758787233,"sku":"10000284","price":95.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/Anipryl-Selegiline-Tablets-for-Dogs-main.png?v=1754000577","url":"https:\/\/hardypaw.com\/en-gb\/products\/anipryl-tablets","provider":"HardyPaw","version":"1.0","type":"link"}