{"product_id":"nuflor-florfenicol-injectable-solution-for-cattle","title":"Nuflor (Florfenicol) Injectable Solution for Cattle","description":"\u003ch2\u003eOriginal FDA-Approved Broad-Spectrum Florfenicol Antibiotic for Cattle\u003c\/h2\u003e\n\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eNuflor (Florfenicol) Injectable Solution 300 mg\/mL is the original FDA-approved prescription broad-spectrum antibiotic for IM and SC use in beef and non-lactating dairy cattle only. Each mL has 300 mg florfenicol, 250 mg NMP, 150 mg propylene glycol, and polyethylene glycol. It treats and controls BRD and foot rot in cattle with no milk or meat withdrawal, available in 100 mL, 250 mL, and 500 mL glass vials.\u003c\/p\u003e\n\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eBRD Treatment:\u003c\/strong\u003e Tackles bovine respiratory disease linked to Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni in cattle.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eBRD Prevention:\u003c\/strong\u003e Keeps respiratory disease from developing in high-risk cattle already exposed to the same three BRD-causing pathogens.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFoot Rot Treatment:\u003c\/strong\u003e Clears bovine interdigital phlegmon caused by Fusobacterium necrophorum and Bacteroides melaninogenicus in beef and dairy cattle.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDual Administration Routes:\u003c\/strong\u003e Administered by IM injection (two doses 48 hours apart) or a single SC injection in the neck.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eBactericidal Activity:\u003c\/strong\u003e Kills Mannheimia haemolytica and Histophilus somni isolates directly rather than just slowing their growth in cattle.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFast Clinical Response:\u003c\/strong\u003e Most treated cattle begin showing clear signs of improvement within 24 hours of the first dose being given.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNo Milk Discard:\u003c\/strong\u003e No milk discard and no preslaughter waiting period when this product is used exactly as the label directs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eVariants\u003c\/h3\u003e\n\u003cp\u003eNuflor Injectable Solution 100 mL (300mg\/ml)\u003c\/p\u003e\n\u003cp\u003eNuflor Injectable Solution 250 mL (300mg\/ml)\u003c\/p\u003e\n\u003cp\u003eNuflor Injectable Solution 500 mL (300mg\/ml)\u003c\/p\u003e\n\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eFlorfenicol: 300 mg per mL\u003c\/p\u003e\n\u003ch4\u003eInactive Ingredients\u003c\/h4\u003e\n\u003cp\u003eN-methyl-2-pyrrolidone (NMP) 250 mg\/mL, propylene glycol 150 mg\/mL, polyethylene glycol qs\u003c\/p\u003e\n\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage and Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e Federal law restricts Nuflor to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eIM Dose:\u003c\/strong\u003e Give 20 mg\/kg (3 mL\/100 lbs) intramuscularly in the neck and repeat the same dose 48 hours later.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSC Dose:\u003c\/strong\u003e Give one 40 mg\/kg (6 mL\/100 lbs) subcutaneous neck injection as a single-dose alternative to IM dosing.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSC BRD Control:\u003c\/strong\u003e For high-risk cattle, give a single 40 mg\/kg (6 mL\/100 lbs) SC neck injection to control BRD before it develops.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNeck Injection Only:\u003c\/strong\u003e Always inject in the neck only as tissue reactions elsewhere on the body tend to be significantly more severe.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003e10 mL Per Site:\u003c\/strong\u003e Never give more than 10 mL at any one injection site regardless of whether the IM or SC route is being used.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eRe-evaluate at 72 Hours:\u003c\/strong\u003e If the animal shows no clear improvement within 72 hours of starting, revisit the diagnosis right away.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eStopper Puncture Limit:\u003c\/strong\u003e The 100 mL vial stopper caps out at 3 punctures; both the 250 mL and 500 mL stoppers allow up to 17.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eUse Within 30 Days:\u003c\/strong\u003e Throw out any unused solution 30 days after the vial was first opened to keep it sterile and safe.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCattle Only:\u003c\/strong\u003e Cleared for IM and SC use in beef and non-lactating dairy cattle only; never give to any other animal species.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFemale Dairy Restriction:\u003c\/strong\u003e Not cleared for female dairy cattle 20 months or older, including dry cows, due to the risk of milk residues.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNot for Veal Calves:\u003c\/strong\u003e Never use in calves destined for veal as no withdrawal period has been set for pre-ruminating calves.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNot for Breeding Animals:\u003c\/strong\u003e The impact of florfenicol on reproductive performance, pregnancy, and lactation in cattle has not been studied.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eTesticular Degeneration Risk:\u003c\/strong\u003e Animal toxicity studies have linked florfenicol to testicular degeneration and atrophy in dogs, rats, and mice.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eIM Slaughter Withdrawal:\u003c\/strong\u003e Cattle must not go to slaughter for human consumption within 28 days of the last intramuscular dose.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSC Slaughter Withdrawal:\u003c\/strong\u003e Cattle treated subcutaneously must stay out of the food supply for at least 38 days after treatment.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHypersensitivity Contraindication:\u003c\/strong\u003e Never give to any animal that has had a prior allergic reaction to florfenicol.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNMP Pregnancy Warning:\u003c\/strong\u003e Pregnant women must wear gloves and avoid contact with Nuflor as NMP has shown reproductive toxicity in repeated animal studies.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSkin and Eye Irritant:\u003c\/strong\u003e Keep off skin, eyes, and clothes; flush eyes for 15 minutes and wash skin with soap if any contact occurs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eReduced Appetite:\u003c\/strong\u003e Some cattle may eat and drink less than usual in the days following Nuflor treatment; this is generally temporary.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eLoose Stools:\u003c\/strong\u003e Brief diarrhea has been reported in cattle after both IM and SC administration at the recommended dose.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eInjection Site Reaction:\u003c\/strong\u003e IM injection can cause local tissue damage lasting past 28 days and may mean losing some edible tissue at slaughter.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eStore Between 2-30°C:\u003c\/strong\u003e No refrigeration needed; keep away from light when not in use to protect product stability.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eUse Within 30 Days:\u003c\/strong\u003e Throw out unused solution 30 days after first opening; never exceed the puncture limit for each vial size.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eKeep Out of Reach:\u003c\/strong\u003e Store in a locked spot away from children and animals to prevent any accidental contact or ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-gb\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-gb\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\n\u003ch3\u003eQ1: What infections does Nuflor florfenicol injection treat in cattle?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Nuflor treats bovine respiratory disease (BRD) caused by Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni, and bovine interdigital phlegmon (foot rot) caused by Fusobacterium necrophorum and Bacteroides melaninogenicus. It also controls BRD in beef and non-lactating dairy cattle at high risk of developing these infections.\u003c\/p\u003e\n\n\u003ch3\u003eQ2: What is the correct Nuflor cattle antibiotic dose and route of administration?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e For IM use, give 20 mg\/kg (3 mL\/100 lbs) twice, 48 hours apart, in the neck only. For SC use, give a single dose of 40 mg\/kg (6 mL\/100 lbs) in the neck only. Do not exceed 10 mL per injection site for either route.\u003c\/p\u003e\n\n\u003ch3\u003eQ3: What are the withdrawal periods for Nuflor florfenicol in beef and dairy cattle?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Cattle treated by IM injection must not be slaughtered for human consumption within 28 days of the last treatment. For SC treatment, the preslaughter withdrawal period is 38 days. No milk discard period applies when the product is used as directed.\u003c\/p\u003e\n\n\u003ch3\u003eQ4: What are the stopper puncture limits for the different Nuflor vial sizes?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The 100 mL vial stopper tops out at 3 punctures while both the 250 mL and 500 mL stoppers can handle up to 17. All three sizes need to be used up within 30 days of first being opened, no matter how many times the stopper has been entered.\u003c\/p\u003e\n\n\u003ch3\u003eQ5: How does Nuflor florfenicol solution differ from Norfenicol for cattle?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Both share the same 300 mg\/mL florfenicol strength and cover the same conditions. Nuflor uses NMP, propylene glycol, and PEG as inactive ingredients while Norfenicol uses 2-pyrrolidone and glycerol formal. The SC withdrawal period is also longer for Nuflor at 38 days versus 33 days for Norfenicol, and Nuflor is the original brand under NADA 141-063.\u003c\/p\u003e","brand":"Merck Animal Health","offers":[{"title":"100-ml (300mg\/ml)","offer_id":44865903952033,"sku":"065549","price":85.0,"currency_code":"GBP","in_stock":true},{"title":"250-ml (300mg\/ml)","offer_id":44865903984801,"sku":"065553","price":187.0,"currency_code":"GBP","in_stock":true},{"title":"500-ml (300mg\/ml)","offer_id":44865904017569,"sku":"065558","price":365.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/nuflor-florfenicol-injectable-solution-for-cattle-100-ml-300mg-ml-207.jpg?v=1777932204","url":"https:\/\/hardypaw.com\/en-gb\/products\/nuflor-florfenicol-injectable-solution-for-cattle","provider":"HardyPaw","version":"1.0","type":"link"}