{"product_id":"pilocarpine-hci-opthalmic-solution-1-15-ml","title":"Pilocarpine HCI Ophthalmic Solution 1% (15 mL)","description":"\u003cp\u003e\u003cimg width=\"700\" alt=\"RX MAP\" class=\"img-responsive\" src=\"https:\/\/hardypaw.com\/cdn\/shop\/files\/rx-map.webp\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch2\u003eCholinergic Eye Drops for Dry Eye and Glaucoma Management in Dogs\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003ePilocarpine HCl 1% Ophthalmic Solution is a prescription cholinergic eye medication used by veterinarians to treat \u003ca href=\"\/en-gb\/collections\/dog-kidney-urinary-medications\" title=\"Dog kidney \u0026amp; urinary tract medications: prevent stones \u0026amp; infections | hardypaw\" aria-label=\"Dog kidney \u0026amp; urinary tract medications: prevent stones \u0026amp; infections | hardypaw\"\u003eneurogenic keratoconjunctivitis sicca\u003c\/a\u003e and primary glaucoma in dogs. It works by activating parasympathetic receptors in the eye and the nerves that drive tear production, which encourages tear secretion and helps aqueous fluid drain more freely to bring eye pressure down. For neurogenic dry eye, this solution is typically given orally in food rather than applied directly to the eye, which sets it apart from most ophthalmic solutions. It is used off-label across all veterinary species.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurogenic Dry Eye Treatment:\u003c\/strong\u003e Encourages tear gland activity in dogs with neurogenic KCS tied to nerve damage or immune-related tear gland dysfunction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlaucoma Pressure Control:\u003c\/strong\u003e Brings elevated intraocular pressure down by tightening the pupil and supporting better aqueous humor drainage in dogs with primary glaucoma.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGentle Lower Concentration:\u003c\/strong\u003e The 1% concentration offers milder cholinergic stimulation, making it a good fit for neurogenic KCS and early or mild glaucoma management.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCranial Nerve Assessment:\u003c\/strong\u003e Helps veterinary ophthalmologists identify cranial nerve III lesions by watching how the pupil responds to this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConvenient Dropper Bottle:\u003c\/strong\u003e A sterile 15mL dropper bottle with around 20 drops per milliliter makes keeping up with consistent daily dosing straightforward for pet owners.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003ePilocarpine Hydrochloride 1%\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003ePilocarpine HCl 1% Ophthalmic Solution is a prescription-only medication. A valid veterinarian prescription is required to purchase this product.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Secondary Glaucoma:\u003c\/strong\u003e Pets with secondary glaucoma should not receive this medication, as it is only suited for primary open-angle glaucoma.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Uveitis and Lens Luxation:\u003c\/strong\u003e Eyes dealing with active uveitis or anterior lens luxation should not receive this medication, as pupil constriction may make both conditions worse.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Retinal Disease:\u003c\/strong\u003e Dogs with a past history of retinal disease, retinal tears, or cataract surgery need a veterinary review before this medication is started.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Systemic Conditions:\u003c\/strong\u003e Pets with heart failure, asthma, hyperthyroidism, epilepsy, stomach ulcers, or urinary obstruction need close monitoring on this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Pregnancy:\u003c\/strong\u003e How this medication affects pregnant or nursing animals is not fully known, so it should only be used with direct veterinary guidance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Dropper Tip Sterile:\u003c\/strong\u003e The dropper tip should be kept well away from the eye, skin, and all surfaces to keep the solution from becoming contaminated.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpace Multiple Eye Medications:\u003c\/strong\u003e Other eye drops being used at the same time should be spaced at least five minutes apart to prevent the drops from interfering with each other.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eConjunctival Redness and Irritation:\u003c\/strong\u003e Some redness and irritation at the application site can come up but tends to clear within a few days in most pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePoor Vision in Dim Light:\u003c\/strong\u003e With the pupil pulled tighter by this medication, less light reaches the eye, which can make it harder for dogs to see in dim conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystemic Toxicity Signs:\u003c\/strong\u003e Heavy drooling, vomiting, diarrhea, increased urination, and irregular heart rhythm may point to systemic absorption and need immediate veterinary attention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAccidental Ingestion Signs:\u003c\/strong\u003e If swallowed, the pet may show heavy salivation, vomiting, diarrhea, and tearing; rinse the mouth and eyes with water and contact a veterinarian right away.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature:\u003c\/strong\u003e Store vials somewhere cool and dry, maintaining a temperature of 59°F to 77°F and keeping them away from heat sources.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect From Light and Freezing:\u003c\/strong\u003e Both direct sunlight and freezing temperatures can break down the solution, so a stable, shaded, and consistently above-freezing spot is best.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCap Secured After Use:\u003c\/strong\u003e Pressing the cap back on firmly after every application keeps the sterile solution protected from contamination between uses.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eNOTE:\u003c\/strong\u003e\u003c\/span\u003e For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca aria-label=\"Shipping policy | hardypaw\" title=\"Shipping policy | hardypaw\" href=\"\/en-gb\/pages\/shipping-policy\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca aria-label=\"Refund policy\" title=\"Refund policy\" href=\"\/en-gb\/policies\/refund-policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: How is pilocarpine 1% used differently from the 4% concentration for dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Pilocarpine 1% is mainly used for neurogenic dry eye in dogs, given orally in food to get tear production going. It can also be applied topically for mild or early glaucoma. The 4% concentration is reserved for primary glaucoma cases where a stronger reduction in intraocular pressure is what the situation calls for.\u003c\/p\u003e\n\u003ch3\u003eQ2: Why is pilocarpine for dry eye given orally rather than as an eye drop in some dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e In neurogenic KCS, the issue lies with the nerves that drive tear production rather than the eye surface itself. Taking the medication orally in food lets it reach those nerve pathways more directly than a topical drop would. A veterinarian will decide whether oral or topical use is the better fit based on the dog's type of dry eye.\u003c\/p\u003e\n\u003ch3\u003eQ3: How will my veterinarian know if pilocarpine is working for my dog's dry eye?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e A veterinarian will check how well the eyes are responding at follow-up visits using the Schirmer tear test to measure tear output and by looking at the overall condition of the eye surface. From there, the dose gets adjusted over time, going up if tear production needs more support and coming down if the body starts showing signs of systemic effects.\u003c\/p\u003e\n\u003ch3\u003eQ4: Can pilocarpine ophthalmic solution be used in cats for dry eye?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Topical use of pilocarpine in cats is generally avoided due to the toxicity risk that comes with standard concentrations. A very dilute oral form may be considered in some cats under close veterinary supervision. A veterinarian will assess whether pilocarpine is a safe and suitable option for the cat's individual condition.\u003c\/p\u003e\n\u003ch3\u003eQ5: What should I do if my dog accidentally ingests pilocarpine solution?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Get in touch with your veterinarian or an animal poison control center right away if a significant amount is swallowed. Heavy salivation, vomiting, diarrhea, and tearing are signs to watch for. Rinsing the mouth and eyes with water is a sensible first step, and getting veterinary help quickly is important rather than waiting to see how things develop.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\u003ca aria-label=\"Visit a webpage about Dailymed - pilocarpine hydrochloride- pilocarpine hydrochloride ophthalmic solution solution\/ drops\" title=\"Dailymed - pilocarpine hydrochloride- pilocarpine hydrochloride ophthalmic solution solution\/ drops\" href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=84428e9a-f486-44d9-ad93-4ea9069a6787\"\u003ehttps:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=84428e9a-f486-44d9-ad93-4ea9069a6787\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca aria-label=\"Visit a webpage about Https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/nda\/2010\/200890s000chemr.pdf\" title=\"Https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/nda\/2010\/200890s000chemr.pdf\" href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/nda\/2010\/200890s000ChemR.pdf\"\u003ehttps:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/nda\/2010\/200890s000ChemR.pdf\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Varies (Generic)","offers":[{"title":"Default Title","offer_id":43337588375713,"sku":"191.56400.3","price":68.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/pilocarpine-hci-ophthalmic-solution-1-15-ml-pet-medicine-406.png?v=1778528837","url":"https:\/\/hardypaw.com\/en-gb\/products\/pilocarpine-hci-opthalmic-solution-1-15-ml","provider":"HardyPaw","version":"1.0","type":"link"}