{"product_id":"tildren-horses-500mg","title":"Tildren 500mg (30 mL) for Horses","description":"\u003cp\u003e\u003cimg border=\"0\" alt=\"Rx Map\" src=\"https:\/\/hardypaw.com\/cdn\/shop\/files\/rx-map.webp\" loading=\"lazy\" data-original=\"https:\/\/hardypaw.com\/cdn\/shop\/files\/rx-map.webp\" data-files=\"rx-map.webp\"\u003e\u003c\/p\u003e\n\u003ch2\u003eSupports Navicular Syndrome Relief in Horses\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eTildren is a veterinary-prescribed treatment that’s administered intravenously to help manage the \u003ca href=\"\/en-gb\/collections\/horse-arthritis-medications\" title=\"Horse arthritis medications: inflammation \u0026amp; joint pain relief | hardypaw\" aria-label=\"Horse arthritis medications: inflammation \u0026amp; joint pain relief | hardypaw\"\u003esymptoms of navicular syndrome in horses\u003c\/a\u003e. It functions by inhibiting the breakdown of bone, which helps in improving comfort and mobility over time. Delivered through a controlled infusion, it acts directly on the bone tissue, and its positive effects may last for several months after the treatment.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNavicular Support:\u003c\/strong\u003e Helps control the clinical signs of navicular syndrome, ultimately improving lameness outcomes for affected horses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBone Resorption Control: \u003c\/strong\u003eWorks by inhibiting the activity of osteoclasts, which helps to \u003ca href=\"\/en-gb\/collections\/horse-arthritis-medications\" title=\"Horse arthritis medications: inflammation \u0026amp; joint pain relief | hardypaw\" aria-label=\"Horse arthritis medications: inflammation \u0026amp; joint pain relief | hardypaw\"\u003ereduce bone resorption\u003c\/a\u003e and promotes healthier bone metabolism over time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProven Effectiveness:\u003c\/strong\u003e Clinical studies have shown that it has higher success rates in improving lameness compared to control groups.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLong Lasting Action: \u003c\/strong\u003eStays in the bone tissue for extended periods, ensuring ongoing therapeutic effects even after just one infusion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargeted IV Therapy\u003c\/strong\u003e: Administered intravenously for precise dosing and controlled delivery under veterinary supervision.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable height=\"79\" style=\"width: 45.4708%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"302\" style=\"width: 74.7932%;\"\u003e\n\u003cp\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 24.991%;\"\u003e\n\u003cp\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"302\" style=\"width: 74.7932%;\"\u003e\n\u003cp\u003eTiludronic acid (as tiludronate disodium)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 24.991%;\"\u003e\n\u003cp\u003e500 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"302\" style=\"width: 74.7932%;\"\u003e\n\u003cp\u003eMannitol USP\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 24.991%;\"\u003e\n\u003cp\u003e250 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eRecommended-Dosage Chart\u003c\/h4\u003e\n\u003ctable height=\"300\" style=\"width: 44.7575%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\" style=\"width: 32.4385%;\"\u003e\n\u003cp\u003e\u003cstrong\u003eWeight Range (lbs)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"353\" style=\"width: 67.1141%;\"\u003e\n\u003cp\u003e\u003cstrong\u003eVolume of Reconstituted Solution (20 mg\/mL)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\" style=\"width: 32.4385%;\"\u003e\n\u003cp\u003e550–770\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"353\" style=\"width: 67.1141%;\"\u003e\n\u003cp\u003e15 mL\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\" style=\"width: 32.4385%;\"\u003e\n\u003cp\u003e771–990\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"353\" style=\"width: 67.1141%;\"\u003e\n\u003cp\u003e20 mL\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\" style=\"width: 32.4385%;\"\u003e\n\u003cp\u003e991–1210\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"353\" style=\"width: 67.1141%;\"\u003e\n\u003cp\u003e25 mL\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\" style=\"width: 32.4385%;\"\u003e\n\u003cp\u003e1211–1430\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"353\" style=\"width: 67.1141%;\"\u003e\n\u003cp\u003e30 mL\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\" style=\"width: 32.4385%;\"\u003e\n\u003cp\u003e1431–1650\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"353\" style=\"width: 67.1141%;\"\u003e\n\u003cp\u003e35 mL\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"171\" style=\"width: 32.4385%;\"\u003e\n\u003cp\u003e1651–1875\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"353\" style=\"width: 67.1141%;\"\u003e\n\u003cp\u003e40 mL\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary Prescription Only\u003c\/strong\u003e: This medication must be administered by or under the supervision of a licensed veterinarian only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeight-Based Dose\u003c\/strong\u003e: Administer a single intravenous dose of 1 mg per kg body weight as prescribed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSlow Infusion Rate\u003c\/strong\u003e: Infuse it slowly and evenly over 90 minutes to help reduce the chances of any adverse reactions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProper Reconstitution\u003c\/strong\u003e: Use sterile saline and ensure the right dilution before administering it through intravenous infusion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid Incompatible Solutions\u003c\/strong\u003e: Avoid mixing it with any solutions that contain calcium or divalent cations.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTimely Administration\u003c\/strong\u003e: Use prepared infusion within 2 hours or refrigerate up to 24 hours before use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRenal Health Risk:\u003c\/strong\u003e Avoid use in horses with poor kidney function since this raises the risk of toxicity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNSAID Interaction Warning:\u003c\/strong\u003e Do not use with NSAIDs because this may increase the chance of acute kidney failure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHydration Requirement: \u003c\/strong\u003eMake sure horses are well-hydrated before treatment to reduce possible kidney damage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalance Risk: \u003c\/strong\u003eUse carefully in \u003ca href=\"\/en-gb\/collections\/horse-hydration-electrolyte-supplements\" title=\"Horse hydration \u0026amp; electrolyte supplements: powder, paste \u0026amp; gels | hardypaw\" aria-label=\"Horse hydration \u0026amp; electrolyte supplements: powder, paste \u0026amp; gels | hardypaw\"\u003ehorses with electrolyte problems\u003c\/a\u003e, as the drug may change calcium, magnesium, and potassium levels.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eYoung Horse Safety: \u003c\/strong\u003eNot tested in horses under four years old and may impact bone growth.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReproductive Safety: \u003c\/strong\u003eAvoid use in pregnant, nursing, or breeding horses due to possible risks to the fetus and development.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eColic Signs: \u003c\/strong\u003eHorses may show temporary abdominal discomfort, such as pawing, rolling, or restlessness, shortly after infusion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrinary Changes: \u003c\/strong\u003eSome horses may drink more or urinate more within hours after administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInjection Reactions: \u003c\/strong\u003eMild swelling or a bruise at the injection site after intravenous administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMuscle Tremors: \u003c\/strong\u003eMuscle twitching or mild tremors may appear within a few hours after infusion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReduced Appetite: \u003c\/strong\u003eThere may be a short-term decrease in appetite or feed intake following treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Reactions: I\u003c\/strong\u003en rare cases, there may be kidney problems or allergic reactions that need immediate veterinary attention.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage\u003c\/strong\u003e: Store unopened vials at a controlled room temperature, ideally ranging from 68°F to 77°F.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRefrigerated Solution Storage\u003c\/strong\u003e: You can safely refrigerate the prepared infusion between 36°F and 46°F for up to 24 hours.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLight Protection\u003c\/strong\u003e: Keep the reconstituted solution protected from light to maintain product stability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUse Within Timeframe\u003c\/strong\u003e: Administer the prepared solution within 2 hours if kept at room temperature for best safety.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/en-gb\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-gb\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What is Tildren used for in horses?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Tildren is used for managing the clinical signs of navicular syndrome in horses, a condition that impacts the navicular bone and nearby structures. It \u003ca href=\"\/en-gb\/collections\/horse-arthritis-medications\" title=\"Horse arthritis medications: inflammation \u0026amp; joint pain relief | hardypaw\" aria-label=\"Horse arthritis medications: inflammation \u0026amp; joint pain relief | hardypaw\"\u003ehelps alleviate lameness\u003c\/a\u003e and enhance comfort by decreasing bone resorption, ultimately supporting improved mobility over time, but it’s important to use it under the care of a veterinarian.\u003c\/p\u003e\n\u003ch3\u003eQ2: How is Tildren administered to horses?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Tildren is given as a slow intravenous infusion at a dose of 1 mg for each kilogram of body weight. The infusion should be given over 90 minutes using proper sterile techniques and veterinary supervision to reduce the risk of adverse reactions.\u003c\/p\u003e\n\u003ch3\u003eQ3: How long does Tildren take to show results?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The maximum therapeutic effect of Tildren may not be observed until up to two months after treatment. The drug works gradually by affecting bone metabolism, and its presence in bone tissue allows for sustained effects over an extended period following a single infusion.\u003c\/p\u003e\n\u003ch3\u003eQ4: Can Tildren be used with NSAIDs in horses?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Tildren should not be used concurrently with NSAIDs due to an increased risk of renal toxicity and acute renal failure. A proper washout period is recommended, and veterinarians should monitor kidney function if any related medications are required during treatment.\u003c\/p\u003e\n\u003ch3\u003eQ5: What are the common side effects of Tildren in horses?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Some common side effects to watch for include temporary signs of colic, such as restlessness, pawing, or rolling. You may also notice an increase in urination, a decrease in appetite, and mild reactions at the injection site. These effects generally happen shortly after the infusion and usually resolve with just a bit of observation or light intervention.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Bimeda","offers":[{"title":"Default Title","offer_id":43365859950753,"sku":"540890","price":278.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/tildren-500mg-30-ml-for-horses-pet-medicine-223.png?v=1778530166","url":"https:\/\/hardypaw.com\/en-gb\/products\/tildren-horses-500mg","provider":"HardyPaw","version":"1.0","type":"link"}