SMZ/TMP (sulfamethoxazole and trimethoprim) 80mg/16mg Injection (30 ml)

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SMZ/TMP (Sulfamethoxazole and Trimethoprim) 80mg/16mg Injection for Dogs and Cats

SMZ/TMP (Sulfamethoxazole and Trimethoprim) is a potent broad-spectrum antibiotic injection used to treat various bacterial infections in dogs, cats, and horses. This medication works by inhibiting the growth of harmful bacteria in the body, targeting infections such as urinary tract infections (UTIs), respiratory infections, gastrointestinal infections, and skin infections. By combining two active ingredients, sulfamethoxazole (a sulfonamide) and trimethoprim (a dihydrofolate reductase inhibitor), this treatment offers dual-action defense against resistant bacterial strains.

Ensuring pets stay hydrated while on this medication is crucial, as it helps reduce the risk of crystal formation in the urine, a known side effect associated with sulfonamides.

All prescription items are Non-Refundable and Non-Returnable.

NOTE: For generic medications, picture displayed may not depict actual product. Manufacturer may vary on this item.

What are the Benefits of SMZ/TMP Injection?

  • Broad-spectrum coverage: Effective against a wide range of bacterial infections, including those affecting the urinary tract, respiratory system, and skin.
  • Dual-action antibiotic: The combination of sulfamethoxazole and trimethoprim works synergistically to fight bacterial resistance.
  • Quick-acting formula: Administered via injection, ensuring faster absorption and onset of action compared to oral tablets.
  • Versatile use: Suitable for multiple species, including dogs, cats, and horses, making it a valuable option for various veterinary infections.
  • Cost-effective: As a generic alternative to branded antibiotics, SMZ/TMP provides a budget-friendly solution without compromising efficacy.

How Do I Use SMZ/TMP Injection for My Pet?

Always consult your veterinarian for precise dosage instructions based on your pet's condition and body weight. Typically administered by injection, the dosage will depend on the severity and type of infection being treated. Veterinary guidance ensures accurate dosing and duration of treatment, reducing the risk of antibiotic resistance.

Ensure your pet has constant access to fresh water throughout the treatment period to prevent dehydration and reduce the risk of crystal formation in the urine.

What Ingredients Are in SMZ/TMP Injection?

  • Sulfamethoxazole: An antibiotic from the sulfonamide class that blocks bacterial synthesis.
  • Trimethoprim: A dihydrofolate reductase inhibitor that prevents bacteria from multiplying by interfering with their folic acid production.

What Are the Side Effects of SMZ/TMP 80mg/16mg Injection?

Like all medications, SMZ/TMP may cause side effects in some pets. Common reactions may include:

  • Decreased appetite
  • Vomiting or diarrhea
  • Increased thirst and urination

More severe side effects can occur, especially with long-term use. Monitor your pet for:

  • Dry eye (keratoconjunctivitis sicca)
  • Jaundice (yellowing of the skin or eyes) due to liver inflammation
  • Fever or anemia
  • Allergic reactions (e.g., hives, facial swelling, joint swelling)
  • Gallbladder dysfunction

If you notice any of these symptoms, contact your veterinarian immediately.

What Precautions Should I Take When Using SMZ/TMP 80mg/16mg Injection?

  • Hydration is key: Ensure your pet drinks plenty of water while on this medication to avoid the risk of urinary crystal formation.
  • Monitor for allergic reactions: Pets allergic to sulfonamides should not take this medication.
  • Liver or kidney disease: If your pet has a history of liver or kidney disease, consult your veterinarian before administering this antibiotic.

How to Store SMZ/TMP (Sulfamethoxazole and Trimethoprim) Injection

Proper storage of SMZ/TMP injection is crucial to maintain its effectiveness and ensure your pet's safety. Follow these guidelines to store the product correctly:

  • Temperature: Store the injection at a controlled room temperature, between 68°F and 77°F (20°C to 25°C). Brief temperature fluctuations between 59°F and 86°F (15°C to 30°C) are permissible but should be avoided if possible.
  • Light exposure: Keep the medication in its original packaging to protect it from direct light, which may degrade the solution over time.
  • Moisture: Avoid storing SMZ/TMP in areas with high humidity, such as bathrooms or near sinks, as moisture can compromise the medication.
  • Child and pet safety: Store in a secure location out of reach of children and pets to prevent accidental ingestion or misuse.
  • Do not freeze: Freezing the medication can alter its effectiveness. Always keep it in a cool, dry place away from extreme temperatures.
  • Check expiration dates: Ensure that the medication is not used past its expiration date. Expired medication may lose potency and could pose risks to your pet’s health.

By following these storage guidelines, you can preserve the integrity of SMZ/TMP and ensure its efficacy when treating your pet. Always consult your veterinarian if you have any concerns about the medication’s storage or usage.

Shipping & Returns 

Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.


FAQs - SMZ/TMP 80mg/16mg Injection 

What is SMZ/TMP (Sulfamethoxazole and Trimethoprim) Injection used for?

SMZ/TMP is used to treat a wide range of bacterial infections in pets, including urinary tract infections (UTIs), respiratory infections, gastrointestinal infections, and skin infections. It combines two antibiotics, sulfamethoxazole and trimethoprim, which work together to inhibit bacterial growth and help your pet recover from these infections.

How does SMZ/TMP work in pets?

SMZ/TMP works by blocking two critical processes in bacterial cells. Sulfamethoxazole interferes with folic acid production, while trimethoprim stops DNA synthesis. Together, they prevent bacteria from multiplying, effectively treating infections and stopping their spread in your pet's body.

How long should my pet stay on SMZ/TMP injection?

The length of treatment depends on the type and severity of the infection being treated. Your veterinarian will provide a specific duration, which may range from several days to a few weeks. It's important to follow the prescribed treatment plan fully, even if your pet seems to improve before finishing the course.

Can SMZ/TMP injection be given to pregnant pets?

SMZ/TMP should be used cautiously in pregnant animals. It may cause complications, especially in the early stages of pregnancy. Always consult your veterinarian before using this medication on pregnant pets to weigh the potential risks and benefits based on your pet's condition.

How soon will I see improvements in my pet after starting SMZ/TMP?

Improvements can typically be seen within a few days of starting SMZ/TMP treatment. However, the timeline can vary based on the infection's severity and the pet's overall health. It’s important to complete the entire prescribed course, even if symptoms improve, to avoid bacterial resistance.

Can SMZ/TMP be used for long-term treatment?

Long-term use of SMZ/TMP is generally avoided unless absolutely necessary, as it can lead to potential side effects like liver damage, kidney issues, or dry eye. If long-term treatment is required, your veterinarian will closely monitor your pet's health and adjust the dosage as needed.

Is SMZ/TMP effective against all types of bacterial infections?

SMZ/TMP is effective against a broad spectrum of bacterial infections but not all. It may not work for infections caused by resistant bacterial strains or certain other pathogens. Your veterinarian will assess the infection and determine if SMZ/TMP is the appropriate treatment.

Are there any drug interactions with SMZ/TMP I should be aware of?

Yes, SMZ/TMP can interact with other medications, such as anticoagulants, diuretics, and some painkillers. Inform your veterinarian about any other drugs or supplements your pet is taking to avoid harmful interactions and ensure the treatment is safe.

What should I do if I miss a dose of SMZ/TMP injection?

If you miss a dose, administer it as soon as you remember. If it’s close to the time for the next dose, skip the missed dose and resume the regular schedule. Do not give a double dose to make up for the missed one, as this can increase the risk of side effects.

Can SMZ/TMP be used to treat fungal or viral infections?

No, SMZ/TMP is specifically designed to treat bacterial infections and is not effective against viral or fungal infections. If your pet has a fungal or viral infection, your veterinarian will prescribe a different type of medication appropriate for that condition.

Clinical Research:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018374s025lbl.pdf

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b89b5502-ce87-45a6-a43c-9891da3cfca4

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