{"title":"Dog Colic \u0026 Musculoskeletal Medications","description":"","products":[{"product_id":"dantrolene-capsules-100mg","title":"Dantrolene Capsules, 100mg","description":"\u003cp\u003e\u003cimg src=\"https:\/\/hardypaw.com\/cdn\/shop\/files\/rx-map.webp\" class=\"img-responsive\" alt=\"RX MAP\" width=\"700\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch2\u003eMuscle Relaxant Capsules for Spasms and Hyperthermia in Pets and Horses\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eDantrolene Sodium 100mg Capsules are a prescription skeletal muscle relaxant used by veterinarians for dogs, cats, and horses. It works by stopping calcium from being released inside skeletal muscle cells, which settles down abnormal contractions and eases muscle spasm. It is used for functional \u003ca href=\"\/en-hk\/collections\/dog-kidney-urinary-medications\" title=\"Dog kidney \u0026amp; urinary tract medications: prevent stones \u0026amp; infections | hardypaw\" aria-label=\"Dog kidney \u0026amp; urinary tract medications: prevent stones \u0026amp; infections | hardypaw\"\u003eurethral obstruction in dogs and cats\u003c\/a\u003e, malignant hyperthermia during anesthesia, canine stress syndrome, and exertional rhabdomyolysis and post-anesthetic myositis in horses, and is prescribed off-label across all veterinary species.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrethral Obstruction Relief:\u003c\/strong\u003e Eases urethral muscle spasm in dogs and cats, helping normal urine flow return and taking the discomfort down with it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMalignant Hyperthermia Treatment:\u003c\/strong\u003e No other medication can address malignant hyperthermia, a rare and potentially fatal anesthetic reaction seen in pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEquine Rhabdomyolysis Prevention:\u003c\/strong\u003e Helps prevent and treat exertional rhabdomyolysis in horses by settling calcium-driven muscle contractions during and after exercise.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost-Anesthetic Myositis Support:\u003c\/strong\u003e Lowers the risk and severity of post-anesthetic myositis in horses coming out of general anesthesia procedures.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo Cardiac or Smooth Muscle Effect:\u003c\/strong\u003e Works specifically on skeletal muscle without touching cardiac or smooth muscle function, making it a more targeted relaxant overall.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eDantrolene Sodium\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eDantrolene Sodium 100mg Capsules are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003cp\u003eTucking this capsule into a soft pill pocket or pill wrap treat is a practical way to get your pet to take their dose without any fuss. Pairing it with food is also a good idea, since it can help keep any stomach discomfort at bay during treatment.\u003c\/p\u003e\n\u003cp\u003e\u003ca aria-label=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" title=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" href=\"\/en-hk\/collections\/dog-pill-pockets\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca aria-label=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" title=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" href=\"\/en-hk\/collections\/cat-pill-pockets\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Liver Disease:\u003c\/strong\u003e Pets with reduced liver function should not be given this medication, as the liver processes it and serious toxicity can develop.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Cardiac and Pulmonary Disease:\u003c\/strong\u003e Pets with significant heart or lung disease need very careful assessment before this medication is considered, or it may need to be avoided entirely.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid Calcium Channel Blockers:\u003c\/strong\u003e This medication should not be given alongside calcium channel blockers like amlodipine, as there have been rare reports of fatal cardiac collapse with this combination.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Pregnancy:\u003c\/strong\u003e This medication is not recommended for pregnant or lactating animals unless a veterinarian has reviewed the situation and confirmed it is needed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCNS Depression Risk:\u003c\/strong\u003e Using this medication alongside benzodiazepines or other tranquilizers may add to central nervous system depression in pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBaseline Bloodwork Required:\u003c\/strong\u003e A veterinarian will often check liver values and potassium levels before starting and at regular points throughout the treatment period.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eSedation and Weakness:\u003c\/strong\u003e Drowsiness, muscle weakness, and general tiredness are among the more commonly seen reactions in dogs and cats on dantrolene.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDigestive Upset:\u003c\/strong\u003e Vomiting, diarrhea, and a drop in appetite can come up during treatment and often ease when the medication is given alongside food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver Toxicity:\u003c\/strong\u003e The liver can be affected by this medication, particularly with longer use, so periodic liver monitoring is an important part of ongoing care.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLow Blood Pressure:\u003c\/strong\u003e A drop in blood pressure has been noted in some pets and can show up as weakness or collapse that needs prompt veterinary attention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDelayed Allergic Sensitivity:\u003c\/strong\u003e Sensitivity to this medication can build up over time, so keeping an eye out for allergic reactions throughout the full course of treatment is important.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature:\u003c\/strong\u003e Capsules do best at room temperature inside a tightly closed container, away from heat, moisture, and direct light.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect From Light and Moisture:\u003c\/strong\u003e Humid conditions and sunlight can wear down the capsule's potency, so a dry, shaded storage spot is the right choice.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOut of Reach:\u003c\/strong\u003e Keep this medication somewhere children and untreated animals in the home cannot get to it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eNOTE: \u003c\/strong\u003e\u003c\/span\u003eFor generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca aria-label=\"Shipping policy | hardypaw\" title=\"Shipping policy | hardypaw\" href=\"\/en-hk\/pages\/shipping-policy\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca aria-label=\"Refund policy\" title=\"Refund policy\" href=\"\/en-hk\/policies\/refund-policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What conditions does dantrolene treat in dogs, cats, and horses?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Dantrolene is used for functional urethral obstruction, malignant hyperthermia during anesthesia, and canine stress syndrome in dogs and cats. In horses, it covers exertional rhabdomyolysis and post-anesthetic myositis. A veterinarian will assess whether it is the right option for your animal's specific condition.\u003c\/p\u003e\n\u003ch3\u003eQ2: Is dantrolene the only treatment for malignant hyperthermia in pets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Dantrolene stands as the only medication that can address malignant hyperthermia, a rare but potentially fatal reaction that can develop under general anesthesia. It works by preventing the surge of calcium inside muscle cells that sets off the dangerous and uncontrolled contractions seen with this condition.\u003c\/p\u003e\n\u003ch3\u003eQ3: Why is liver monitoring important during dantrolene treatment in pets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Since the liver handles the breakdown of this medication, prolonged use can put strain on liver function and lead to hepatotoxicity. A veterinarian will usually run liver enzyme checks before starting and at regular intervals during treatment. Yellowing of the eyes, ongoing vomiting, or a complete loss of appetite should be flagged right away.\u003c\/p\u003e\n\u003ch3\u003eQ4: Can dantrolene be given to pets with heart disease?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Pets with significant cardiac or pulmonary disease need very careful evaluation before being put on this medication, and it may need to be avoided entirely. Combining it with calcium channel blockers like amlodipine is also off the table, as there are documented cases of fatal cardiac collapse when the two are used together.\u003c\/p\u003e\n\u003ch3\u003eQ5: How quickly does dantrolene work in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Dantrolene is short-acting and typically clears from the system within 24 hours of the last dose, though this may stretch longer in pets with kidney or liver conditions. For urgent situations like malignant hyperthermia, the intravenous form is used for speed. The oral capsule is reserved for non-emergency and preventive use.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\u003ca aria-label=\"Visit a webpage about Https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/017443s043s046s048s049lbl.pdf\" title=\"Https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/017443s043s046s048s049lbl.pdf\" href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/017443s043s046s048s049lbl.pdf\"\u003ehttps:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/017443s043s046s048s049lbl.pdf\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca aria-label=\"Visit a webpage about Https:\/\/www.tga.gov.au\/resources\/section-19a-approvals\/dantrium-dantrolene-sodium-25mg-capsules-norgine\" title=\"Https:\/\/www.tga.gov.au\/resources\/section-19a-approvals\/dantrium-dantrolene-sodium-25mg-capsules-norgine\" href=\"https:\/\/www.tga.gov.au\/resources\/section-19a-approvals\/dantrium-dantrolene-sodium-25mg-capsules-norgine\"\u003ehttps:\/\/www.tga.gov.au\/resources\/section-19a-approvals\/dantrium-dantrolene-sodium-25mg-capsules-norgine\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Varies (Generic)","offers":[{"title":"1 capsule","offer_id":43337608724641,"sku":"273507-1","price":1.45,"currency_code":"USD","in_stock":true},{"title":"100 capsules","offer_id":43337608757409,"sku":"273507","price":135.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/dantrolene-capsules-100mg-pet-medicine-677.png?v=1778528883"}],"url":"https:\/\/hardypaw.com\/en-hk\/collections\/dog-colic-musculoskeletal-medications.oembed","provider":"HardyPaw","version":"1.0","type":"link"}