{"product_id":"atopica-for-dogs-10-25-50-100mg","title":"Atopica for Dogs - Cyclosporine Capsules","description":"\u003ch2\u003eFDA-Approved Cyclosporine Capsules for Dogs with Atopic Dermatitis\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eAtopica (Cyclosporine Capsules) USP Modified is an FDA-approved prescription oral immunomodulating capsule for dogs weighing at least 4 lbs. It works by targeting the immune pathway responsible for atopic dermatitis, suppressing the overreaction that causes persistent itching and skin inflammation. Available in four weight-appropriate strengths, 10 mg, 25 mg, 50 mg, and 100 mg, each supplied in 15 unit-dose blister packs.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargeted Immune Action:\u003c\/strong\u003e Suppresses T-helper and T-suppressor cells and inhibits interleukin-2, addressing allergic skin overreaction at its source.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot a Steroid:\u003c\/strong\u003e Moderates immune function without reducing blood cell production or phagocytic activity the way corticosteroids do.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Proven Results:\u003c\/strong\u003e CADESI scores dropped 45% in treated dogs over 30 days versus a 9% worsening in placebo dogs across 265 study participants.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePruritus Improvement:\u003c\/strong\u003e Itching scores improved in 74% of treated dogs after 30 days, compared to only 24% in the placebo group.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Tapering Option:\u003c\/strong\u003e After 30 days, dosing can shift to every other day or twice weekly, reducing overall long-term exposure for your dog.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeight-Specific Sizing:\u003c\/strong\u003e Four capsule strengths are matched to weight ranges so each dog receives a full capsule at the right dose every time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReversible Gum Changes:\u003c\/strong\u003e Gingival hyperplasia noted on daily dosing showed clear improvement once dogs moved to a less frequent maintenance schedule.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eCyclosporine\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e Federal law restricts Atopica to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDogs Only:\u003c\/strong\u003e These capsules are approved for oral use in dogs only; never give them to cats or any other animal species.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStarting Dose:\u003c\/strong\u003e Administer 5 mg\/kg once daily for 30 days using the weight-appropriate capsule strength from the product insert dose table.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEmpty Stomach Needed:\u003c\/strong\u003e Give at least one hour before a meal or two hours after to ensure consistent absorption and reliable therapeutic effect.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGI Upset Adjustment:\u003c\/strong\u003e If vomiting occurs, the vet may suggest a brief pause, dose splitting, or temporary administration with a small amount of food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTaper After 30 Days:\u003c\/strong\u003e Once a good response is seen, the schedule gradually shifts to every other day and eventually to twice weekly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo Double Dosing:\u003c\/strong\u003e A missed dose should be given as soon as remembered, but never give two doses on the same day.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Capsules Whole:\u003c\/strong\u003e Do not break or open capsules; wear gloves when handling them and wash hands thoroughly with soap and water afterward.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKilled Vaccines Only:\u003c\/strong\u003e During treatment, dogs should only receive killed vaccines as the effects on modified live vaccine responses are not yet fully known.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eCancer History Contraindication:\u003c\/strong\u003e Do not use in any dog with a history of neoplasia, as this immunosuppressant may increase susceptibility to cancer development.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity Contraindication:\u003c\/strong\u003e Do not use in dogs with a known hypersensitivity to cyclosporine; anaphylaxis and allergic edema have been reported post-approval.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfection and Cancer Risk:\u003c\/strong\u003e As a systemic immunosuppressant, it may increase susceptibility to infections and the potential for neoplasia development or worsening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Dogs Excluded:\u003c\/strong\u003e Safety has not been established in breeding, pregnant, or nursing dogs; avoid use in these animals entirely.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAge and Weight Limits:\u003c\/strong\u003e Dogs younger than 6 months or below 4 lbs fall outside the established safety and effectiveness data for this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interaction Risk:\u003c\/strong\u003e Atopica is metabolised through the P-450 system; azole antifungals like ketoconazole can raise cyclosporine plasma levels noticeably.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiabetic Dogs Caution:\u003c\/strong\u003e Blood glucose may rise during treatment; diabetic dogs need close monitoring, and tapering or stopping may be required.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRenal Insufficiency Caution:\u003c\/strong\u003e The effect of cyclosporine in dogs with kidney problems has not been studied; proceed carefully in dogs with renal insufficiency.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eVomiting:\u003c\/strong\u003e Reported in 30.9% of dogs in the field study; most cases resolved on their own as treatment continued over time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Around 20% of study dogs experienced diarrhea, though it generally passed without major veterinary intervention being needed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEar Infections:\u003c\/strong\u003e Persistent otitis externa was noted in roughly 6.8% of study dogs; new cases required separate otic treatment alongside Atopica therapy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGum Overgrowth:\u003c\/strong\u003e Gingival hyperplasia was reported in 2.3% of dogs; it was dose-dependent and regressed after tapering to a lower maintenance frequency.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeoplasia Reports:\u003c\/strong\u003e Lymphoma and mast cell tumors have been reported post-approval; it is not confirmed whether these were pre-existing or developed during treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiabetes Mellitus:\u003c\/strong\u003e Reported in post-approval experience; West Highland White Terriers are the most frequently reported breed for this side effect.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrinary Tract Infections:\u003c\/strong\u003e Reported in 3.8% of field study dogs; monitor for signs of urinary tract infection throughout the course of immunosuppressive therapy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurological Signs:\u003c\/strong\u003e Convulsions, muscle tremors, and ataxia have been reported post-approval; seek immediate veterinary care if any neurological signs develop.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Store in the original unit-dose blister container at a controlled room temperature between 59-77°F (15-25°C) at all times.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Original Packaging:\u003c\/strong\u003e Capsules must stay in the original blister pack until administration; do not transfer to secondary containers or pill organizers.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecure Away from Others:\u003c\/strong\u003e Store in a location out of reach of children and all animals to prevent accidental ingestion of these immunosuppressive capsules.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-hk\/pages\/shipping-policy\" target=\"_blank\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-hk\/policies\/refund-policy\" target=\"_blank\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What is Atopica cyclosporine used for in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Atopica is an FDA-approved prescription capsule for managing atopic dermatitis in dogs weighing at least 4 lbs. It targets the immune pathway causing allergic skin reactions, reducing persistent itching, inflammation, and lesions rather than just masking symptoms with steroids or antihistamines.\u003c\/p\u003e\n\u003ch3\u003eQ2: What is the correct Atopica cyclosporine dose for dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The starting dose is 5 mg\/kg given once daily for 30 days using the weight-appropriate capsule. After 30 days, the vet may taper to every other day, then twice weekly, finding the lowest frequency that keeps the condition under control long term.\u003c\/p\u003e\n\u003ch3\u003eQ3: Why must Atopica cyclosporine capsules be given on an empty stomach?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Food in the stomach interferes with how cyclosporine is absorbed in the gut. Giving the capsule at least one hour before eating or two hours after keeps absorption consistent. If vomiting is a concern, the vet may allow temporary administration with a small amount of food.\u003c\/p\u003e\n\u003ch3\u003eQ4: Can Atopica cyclosporine be used in dogs with a history of cancer?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No. Atopica is contraindicated in dogs with any prior history of neoplasia. As a systemic immunosuppressant, it may raise susceptibility to infections and cancer development. Post-approval reports have included lymphoma and mast cell tumor cases, though a direct causal link has not been confirmed.\u003c\/p\u003e\n\u003ch3\u003eQ5: Can my dog receive vaccines while taking Atopica cyclosporine?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Only killed vaccines are recommended during Atopica treatment. Dogs on cyclosporine at higher doses did not mount an antibody response to modified live vaccines, while all dogs responded normally to a killed rabies vaccine. Always discuss the vaccination schedule with your vet.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.drugs.com\/pro\/atopica.html\" target=\"_blank\" rel=\"noopener\" title=\"Https:\/\/www.drugs.com\/pro\/atopica.html\" aria-label=\"Visit a webpage about Https:\/\/www.drugs.com\/pro\/atopica.html\"\u003ehttps:\/\/www.drugs.com\/pro\/atopica.html\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3995266\/\" target=\"_blank\" rel=\"noopener\" title=\"Life-long diseases need life-long treatment: long-term safety of ciclosporin in canine atopic dermatitis - pmc\" aria-label=\"Visit a webpage about Life-long diseases need life-long treatment: long-term safety of ciclosporin in canine atopic dermatitis - pmc\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3995266\/\u003c\/a\u003e\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"10-mg \/ 15 capsules","offer_id":44199171358881,"sku":"CA491507VAM","price":354.0,"currency_code":"HKD","in_stock":true},{"title":"10-mg \/ 30 capsules","offer_id":44199171457185,"sku":"CA491507VAM-PK2","price":707.0,"currency_code":"HKD","in_stock":true},{"title":"10-mg \/ 60 capsules","offer_id":44199171489953,"sku":"CA491507VAM-PK4","price":1414.0,"currency_code":"HKD","in_stock":true},{"title":"25-mg \/ 15 capsules","offer_id":44994568781985,"sku":"CA491007VAM","price":404.0,"currency_code":"HKD","in_stock":true},{"title":"25-mg \/ 30 capsules","offer_id":44994568814753,"sku":"CA491007VAM-PK2","price":807.0,"currency_code":"HKD","in_stock":true},{"title":"25-mg \/ 60 capsules","offer_id":44994568847521,"sku":"CA491007VAM-PK4","price":1614.0,"currency_code":"HKD","in_stock":true},{"title":"50-mg \/ 15 capsules","offer_id":44994568880289,"sku":"CA490507VAM","price":564.0,"currency_code":"HKD","in_stock":true},{"title":"50-mg \/ 30 capsules","offer_id":44994568913057,"sku":"CA490507VAM-PK2","price":1127.0,"currency_code":"HKD","in_stock":true},{"title":"50-mg \/ 60 capsules","offer_id":44994568945825,"sku":"CA490507VAM-PK4","price":2254.0,"currency_code":"HKD","in_stock":true},{"title":"100-mg \/ 15 capsules","offer_id":44994568978593,"sku":"CA490207VAM","price":966.0,"currency_code":"HKD","in_stock":true},{"title":"100-mg \/ 30 capsules","offer_id":44994569011361,"sku":"CA490207VAM-PK2","price":1931.0,"currency_code":"HKD","in_stock":true},{"title":"100-mg \/ 60 capsules","offer_id":44994569044129,"sku":"CA490207VAM-PK4","price":3862.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/atopica-for-dogs-cyclosporine-capsules-pet-medicine-163.png?v=1777915120","url":"https:\/\/hardypaw.com\/en-hk\/products\/atopica-for-dogs-10-25-50-100mg","provider":"HardyPaw","version":"1.0","type":"link"}