Bravecto Topical Solution for Large Cats 13.8-27.5 lbs

12-Week Flea and Tick Spot-On Treatment for Large Cats (13.8–27.5 lbs)

Product Description

Bravecto Topical Solution (Purple Box) is an FDA-approved, prescription-only spot-on flea and tick treatment for cats and kittens 6 months or older, weighing 13.8 to 27.5 pounds. Each single-use tube holds 500 mg of fluralaner, the highest dose in the Bravecto cat range, which enters the bloodstream after application and kills fleas and ticks when they bite. One tube covers 12 weeks of flea and black-legged tick protection and 8 weeks of American dog tick control.

Benefits

• 12-Week Flea Protection: A single application wipes out adult fleas and keeps flea infestations from taking hold for a full 12 weeks.
• Kills Fleas Fast: Fluralaner reaches 100% flea kill effectiveness within 8 hours of application, bringing rapid relief to large cats.
• Black-Legged Tick Control: Treats and controls Ixodes scapularis (black-legged tick) infestations for 12 continuous weeks following a single dose.
• Asian Longhorned Tick Coverage: The first and only product in the US to protect cats against the Asian longhorned tick for a full 12 weeks.
• American Dog Tick Control: Also manages Dermacentor variabilis (American dog tick) infestations for 8 weeks after each application.
• Reduces Flea Allergy Dermatitis: Large cats with flea allergy dermatitis showed clear improvement in skin signs after flea infestations were brought under control with fluralaner.
• No-Spill Applicator: The Twist'n'Use applicator is designed to prevent spills and makes the whole application process straightforward for cat owners.

Ingredients

Composition Table

Other Ingredients

Dimethylacetamide, Glycofurol, Diethyltoluamide, Acetone

How to Use

Directions for Use

• Prescription Required: Federal law limits this product to use by or under the direct order of a licensed veterinarian only.
• Minimum Dose: Put on topically once every 12 weeks, delivering a minimum of 18.2 mg/lb (40 mg/kg) of body weight per application.
• Wear Gloves: Always put on gloves before applying this product and wash both hands thoroughly with soap and water straight after.
• Open the Tube Correctly: Hold the tube upright with the cap tip facing up and give the cap one full turn to break the seal; leave the cap on.
• Position Your Cat: Get your cat standing or lying flat with their back level and still before starting the application process.
• Apply at Skull Base: Part the fur at the base of the skull, press the tube tip straight down against the skin, and squeeze gently to release the solution.
• Avoid Run-Off: Do not deposit too much solution in a single spot; if any runs off, put the remaining amount just behind the first application point.
• American Dog Tick Exposure: For cats regularly in contact with American dog ticks, this product can be applied every 8 weeks rather than the standard 12.
• Open Pouch Just Before Use: Keep the tube sealed inside its foil pouch right up until the moment of application to protect it from moisture.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Minimum Age and Weight: Only use on cats and kittens that are at least 6 months old and weigh no less than 2.6 pounds.
• Neurological History Caution: Take extra care when using this product on cats that have any past history of neurological conditions such as seizures or tremors.
• Topical Use Only: This solution is for skin application only; never let cats lick or swallow any part of this product.
• Breeding and Pregnant Cats: Safety in breeding, pregnant, or nursing cats has not been confirmed; always check with your vet before treating cats in any of these situations.
• American Dog Tick Limit: Coverage against American dog ticks does not extend beyond 8 weeks after dosing; plan re-application timing accordingly with your vet.
• Keep Children Away: Children should not come into contact with the treated area on your cat until the application site has dried out completely.
• Water Immersion Efficacy: How well this product holds up after bathing or water exposure has not been formally tested; factor this into your cat's routine.
• Highly Flammable: Keep the tube away from heat sources, open flames, sparks, and anything else that could cause ignition at all times.

Possible Side Effects

• Vomiting and Diarrhea: Digestive upset including vomiting and loose stools are among the most frequently reported reactions seen in treated cats.
• Application Site Reactions: Hair loss, redness, skin irritation, lesions, or localised redness at the treated spot have been reported following application.
• Lethargy and Anorexia: Some cats may show reduced energy, a decreased interest in food, or prolonged drowsiness in the period following treatment.
• Hypersalivation: Excessive drooling has been reported in some cats, most often as a result of grooming the treated area on their body.
• Neurological Reactions: Rare instances of poor coordination, muscle tremors, and behavioural shifts such as hiding, hyperactivity, or unusual vocalisation have been reported.
• Greasy Application Site: A greasy or damp-looking patch at the treated spot is a normal cosmetic effect and not a cause for concern.

Storage Information

• Store Below 77°F: Keep this product in a location that stays under 77°F (25°C) and away from direct sunlight or excessive heat at all times.
• Keep in Original Packaging: Store the tube inside its original foil pouch to shield the solution from moisture right up until it is needed.
• Safe Storage Practice: Keep this prescription product fully out of reach of children and other household pets to prevent any accidental contact or ingestion.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What does Bravecto (Purple Box) treat and prevent in large cats?

Ans: Bravecto (Purple Box) kills adult fleas and controls flea infestations for 12 weeks. It also tackles black-legged ticks and Asian longhorned ticks for 12 weeks, and American dog ticks for 8 weeks. One tube covers cats weighing between 13.8 and 27.5 pounds.

Q2: How does the Purple Box differ from the Blue Box for medium cats?

Ans: The Purple Box holds 500 mg fluralaner, the highest dose across the Bravecto cat range, while the Blue Box for medium cats contains 250 mg. Both deliver the same duration of flea and tick protection. Always match the tube to your cat's current body weight before applying.

Q3: My large cat weighs more than 27.5 lbs. Can I still use Bravecto?

Ans: Yes. Cats above 27.5 pounds can be treated using the right combination of available Bravecto tube sizes to reach the correct total dose, as directed by your vet. Never rely on a single Purple Box tube alone for a cat above that weight. Always confirm the dosing plan with your veterinarian first.

Q4: How quickly does Bravecto topical start killing fleas on large cats?

Ans: Bravecto reaches full flea kill effectiveness within 8 hours of being applied. In controlled laboratory studies, live flea counts dropped by over 98% within 12 hours after treatment. This rapid action helps disrupt the flea life cycle very early on.

Q5: Is Bravecto topical safe for pregnant or breeding large cats?

Ans: Safety in pregnant, nursing, or breeding cats has not been formally confirmed through dedicated studies. If your large cat falls into any of these categories, speak with your veterinarian before starting any flea and tick treatment program that includes fluralaner-based products.

Q6: Can Bravecto topical for large cats be used with other medications?

Ans: No specific drug interactions were flagged in field trials when this product was used alongside commonly prescribed cat medications. Your veterinarian is best placed to advise on whether this product is safe to combine with any other treatments your cat is currently receiving.

Clinical Research

Fluralaner Pharmacology – NIH

FDA Approval NADA 141-459 – Animal Drugs @ FDA

Flea Allergy Dermatitis in Cats – Merck Veterinary Manual

Tick-Borne Illnesses in Cats – Cornell Feline Health Center