{"product_id":"bravecto-topical-solution-for-dogs-44-88-lbs","title":"Bravecto Topical Solution for Large Dogs 44-88 lbs","description":"\u003ch2\u003e12-Week Flea and Tick Spot-On Protection for Large Dogs\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eBravecto Topical Solution (Blue Box) is an FDA-approved, prescription-only spot-on for dogs and puppies 6 months or older weighing 44 to 88 lbs. Each single-use tube holds 1000 mg of fluralaner, which absorbs through the skin into the bloodstream and gets to work when fleas and ticks feed on your dog. One application keeps fleas and three major tick species away for 12 weeks, and lone star ticks covered for 8 weeks.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003e12-Week Flea Protection:\u003c\/strong\u003e Kills adult fleas and stops Ctenocephalides felis infestations from taking hold for a full 12 weeks from a single application.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast-Acting Formula:\u003c\/strong\u003e Fleas start dying within 2 hours of application and ticks within 12 hours, so large dogs get noticeable relief quickly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlack-Legged Tick Control:\u003c\/strong\u003e A single dose keeps Ixodes scapularis black-legged tick infestations under control for 12 weeks.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAmerican and Brown Dog Tick Control:\u003c\/strong\u003e One application covers American dog ticks (Dermacentor variabilis) and brown dog ticks (Rhipicephalus sanguineus) for 12 weeks.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLone Star Tick Control:\u003c\/strong\u003e Amblyomma americanum lone star ticks are also covered, with each application keeping them controlled for 8 weeks from the dosing date.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWater-Resistant After 3 Days:\u003c\/strong\u003e Bathing or swimming at least 3 days after applying does not affect protection against fleas and Ixodes ricinus ticks.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafe for MDR1 Dogs:\u003c\/strong\u003e Confirmed safe in dogs carrying the MDR1 gene mutation, which makes certain medications harder for some breeds to tolerate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo-Spill Applicator:\u003c\/strong\u003e The Twist'n'Use applicator requires no cap removal, making dosing simple and clean even for larger breeds.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 43.6349%; height: 30px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 38.5211%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 61.2017%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 38.5211%; height: 19.6023px;\"\u003eFluralaner\u003c\/td\u003e\n\u003ctd style=\"width: 61.2017%; height: 19.6023px;\"\u003e1000 mg per tube\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eOther Ingredients\u003c\/h4\u003e\n\u003cp\u003eDimethylacetamide, Glycofurol, Diethyltoluamide, Acetone\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDirections for Use\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e Federal law limits this product to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimum Dose:\u003c\/strong\u003e One application every 12 weeks delivers a minimum of 11.4 mg\/lb (25 mg\/kg) of body weight per dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWear Gloves:\u003c\/strong\u003e Wear gloves throughout the application and give your hands and any skin that came into contact with the product a thorough soap and water wash once you are done.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOpen the Tube Correctly:\u003c\/strong\u003e Hold the tube upright with the cap tip pointing up, then give the cap one full turn to break the seal; the cap remains on throughout the application.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePosition Your Dog:\u003c\/strong\u003e Your dog should be standing or lying flat with their back level before you begin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApply Along the Back:\u003c\/strong\u003e Part the coat between the shoulder blades, press the tube tip directly onto the skin, and work the solution across several spots along the backline.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid Run-Off:\u003c\/strong\u003e Spread the solution across multiple spots rather than squeezing it all into one area, which is especially important for large dogs to prevent run-off.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLone Star Tick Exposure:\u003c\/strong\u003e Dogs regularly in contact with lone star ticks can be dosed every 8 weeks rather than every 12 weeks.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOpen Pouch Just Before Use:\u003c\/strong\u003e Only take the tube out of its sealed foil pouch at the time of application to protect the solution from moisture damage.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ciframe width=\"560\" height=\"315\" src=\"https:\/\/www.youtube.com\/embed\/qlf1YhhtitQ?si=jfikZrhWucj1kX-r\" title=\"YouTube video player\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen\u003e\u003c\/iframe\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimum Age and Weight:\u003c\/strong\u003e Only suitable for dogs and puppies that have reached 6 months of age and weigh at least 4.4 lbs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSeizure History:\u003c\/strong\u003e Extra caution is needed for dogs with a seizure or neurological history; seizures have also been reported in dogs with no prior history.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTopical Use Only:\u003c\/strong\u003e For external skin use only; never give orally and prevent your dog from licking the treated area.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding and Pregnant Dogs:\u003c\/strong\u003e Adverse events have been reported after use in breeding females; speak to your vet before applying to breeding, pregnant, or nursing dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLone Star Tick Limit:\u003c\/strong\u003e Coverage against lone star ticks does not extend beyond 8 weeks; shorten the dosing interval if your dog is regularly exposed to this species.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Children Away:\u003c\/strong\u003e Allow at least 2 hours to pass before letting children near the area where the product was applied.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDogs Only:\u003c\/strong\u003e Never apply the dog formulation to cats; dog products used on cats can cause serious adverse reactions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHighly Flammable:\u003c\/strong\u003e Store and handle the tube well away from heat sources, open flames, sparks, and any other ignition risk.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eVomiting and Diarrhea:\u003c\/strong\u003e Digestive upset including vomiting and loose stools are among the most frequently reported reactions after treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHair Loss and Skin Reactions:\u003c\/strong\u003e Hair loss at the treated spot, moist dermatitis, rash, redness, flaking, and scabbing have been reported following use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy and Decreased Appetite:\u003c\/strong\u003e A drop in energy levels and reduced interest in food have been noted in some dogs after dosing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurological Reactions:\u003c\/strong\u003e Seizures, tremors, and loss of coordination have been reported in rare cases; get in touch with your vet straight away if any of these appear.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGreasy Application Site:\u003c\/strong\u003e A greasy, matted, or wet-looking area at the treated spot is a common cosmetic effect and not a reason for concern.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eStore Below 77°F:\u003c\/strong\u003e Do not store above 25°C (77°F) and keep away from direct sunlight and excessive heat.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep in Original Packaging:\u003c\/strong\u003e The tube should stay sealed in its foil pouch and only be taken out at the time of application to protect it from moisture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away from Children:\u003c\/strong\u003e Store this prescription product somewhere children and other pets cannot reach it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-hk\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-hk\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What does Bravecto Topical Solution (Blue Box) treat and prevent in large dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Bravecto Blue Box kills adult fleas and prevents flea infestations for 12 weeks from one dose. It also controls black-legged ticks, American dog ticks, and brown dog ticks for 12 weeks, and lone star ticks for 8 weeks. It is designed for dogs weighing 44 to 88 lbs dosed once every 12 weeks.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does the Blue Box differ from the Green Box?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The Blue Box holds 1000 mg of fluralaner for large dogs in the 44 to 88 lb range, while the Green Box contains 500 mg for medium dogs up to 44 lbs. Both deliver the same 12-week flea and tick coverage. Always choose the tube that reflects your dog's current weight for accurate dosing.\u003c\/p\u003e\n\u003ch3\u003eQ3: How does Bravecto Topical work in large dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Once applied, fluralaner absorbs through the skin and spreads through the bloodstream. When fleas or ticks bite and feed, they take in fluralaner, which shuts down their nervous system by blocking chloride channels, leading to paralysis and death. This systemic protection holds for a full 12 weeks.\u003c\/p\u003e\n\u003ch3\u003eQ4: Is Bravecto Topical water-resistant for large dogs that swim or bathe frequently?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes. Bathing or swimming at least 3 days after applying does not reduce protection against fleas and Ixodes ricinus ticks. Waiting 3 days before the first wash after dosing is all that is needed, which is a practical advantage for active large-breed dogs that spend time outdoors or in water.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is Bravecto Topical safe for breeding or pregnant large dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Adverse events have been reported in breeding females after use. Safety in breeding, pregnant, and lactating dogs was assessed using the oral formulation. Always consult your veterinarian before applying Bravecto Topical to any large dog that is pregnant, nursing, or being used for breeding purposes.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/1277\"\u003eBravecto Veterinary Approval\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4494331\/\" title=\"Loading and unloading finishing pigs: effects of bedding types, ramp angle, and bedding moisture - pmc\" aria-label=\"Visit a webpage about Loading and unloading finishing pigs: effects of bedding types, ramp angle, and bedding moisture - pmc\"\u003eFluralaner Use in Dogs\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/capcvet.org\/\" title=\"Companion animal parasite council | home\" aria-label=\"Visit a webpage about Companion animal parasite council | home\"\u003eCompanion Animal Parasite Council (CAPC)\u003c\/a\u003e\u003c\/p\u003e","brand":"Merck Animal Health","offers":[{"title":"1 Tube","offer_id":44112577691809,"sku":"158345-MER","price":558.0,"currency_code":"HKD","in_stock":true},{"title":"2 Tubes","offer_id":44112577724577,"sku":"158345-MER-PK2","price":1115.0,"currency_code":"HKD","in_stock":true},{"title":"4 Tubes","offer_id":44112577757345,"sku":"158345-MER-PK4","price":2229.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/bravecto-topical-solution-for-large-dogs-44-88-lbs-1-tube-pet-medicine-725.jpg?v=1778103332","url":"https:\/\/hardypaw.com\/en-hk\/products\/bravecto-topical-solution-for-dogs-44-88-lbs","provider":"HardyPaw","version":"1.0","type":"link"}