Phenylbutazone 20% Injection for Musculoskeletal Pain Relief in Horses

Product Description

Phenylbutazone 20% Injection, widely called Bute, is a prescription-only, FDA-approved NSAID for horses. By cutting off prostaglandin production, it tackles pain, swelling, and fever tied to musculoskeletal problems. At 200 mg/mL given intravenously, it moves through the body fast, making it a go-to option for horses struggling with lameness, joint trouble, tendon damage, or acute laminitis.

Benefits

• Rapid Anti-Inflammatory Relief: Brings down musculoskeletal inflammation in horses, with a visible clinical response typically seen within 24 hours of the first dose.
• Effective Pain Management: Delivers pain relief across a broad range of equine conditions including lameness, arthritis, tendonitis, joint pain, and soft tissue injuries.
• Fever Reduction: Acts as an antipyretic to bring elevated body temperature down in horses running a fever alongside inflammatory conditions.
• Acute Laminitis Support: Widely used under veterinary direction to help keep pain under control during acute laminitis episodes in horses.
• Non-Hormonal Formula: As a pyrazolone derivative with no connection to steroid hormones, it delivers targeted anti-inflammatory action free from hormonal side effects.

Ingredients

Composition Table

How to Use

Directions for Use

Phenylbutazone 20% Injection is a prescription-only medication. A valid veterinarian prescription is required to purchase this product. Please follow your veterinarian's instructions carefully for the dosage and administration of this medication.

Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Your veterinarian should be contacted before starting or modifying any medication for your horse.

Additional Information

Precautions

• Intravenous Use Only: This injection must be given intravenously only; subcutaneous or intramuscular delivery can trigger severe tissue necrosis and serious complications in horses.
• Not for Food Animals: This product must never be used in horses intended for slaughter or destined for human food consumption at any point in time.
• Hypersensitive Horses: Do not give to any horse with a known allergy or sensitivity to phenylbutazone or any other component of this formulation.
• Avoid in Certain Conditions: Keep away from horses with stomach ulcers, anaemia, bone marrow disease, kidney, liver, or heart problems, or pregnant and lactating mares unless benefits clearly outweigh the risks.
• Drug Interactions: Do not combine with other NSAIDs such as flunixin meglumine, ketoprofen, or meloxicam, as doing so sharply raises the risk of gastrointestinal and kidney injury.
• Fresh Water Access: Make sure horses always have clean water available throughout treatment, since dehydration raises the risk of kidney damage from this medication.
• Prescription Only: Federal law limits this product to use by or under the direct order of a licensed veterinarian without exception.

Possible Side Effects

• Gastrointestinal Ulcers: Long-term use can result in stomach or colonic ulcers by reducing prostaglandins that normally protect the gastrointestinal lining in horses.
• Right Dorsal Colitis: May show up as loose stools, dehydration, low energy, reduced appetite, dark mucous membranes, and a faster-than-normal heart rate in affected horses.
• Kidney Damage: Extended use or use in horses that are dehydrated can put kidney function under strain, sometimes changing drinking or urination patterns noticeably.
• Low Blood Protein: Hypoproteinemia may develop, showing up as unexplained body weight loss or fluid-related swelling in the limbs of treated horses.
• Injection Site Reactions: Swelling, local inflammation, and wound formation at the injection site are possible when this product is administered intravenously.
• Allergic Reactions: Facial swelling, hives, sudden loose stools, pale gums, or cold limbs may signal an allergic response; contact your veterinarian without delay if these appear.

Storage Information

• Refrigeration Required: This product must be kept in a refrigerator sitting between 36°F and 46°F (2°C to 8°C) consistently throughout its shelf life.
• Safe Storage Practice: Store this prescription medication in a locked or secure area that children cannot access under any circumstances.
• For Horses Only: This product is made exclusively for use in horses and must not be given to any other animal species or handled by humans for personal use.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Phenylbutazone 20% Injection used for in horses?

Ans: Bute injection is an FDA-approved NSAID that tackles a wide range of musculoskeletal issues in horses. Vets reach for it when horses are dealing with lameness, arthritis, tendonitis, joint injuries, soft tissue pain, or the discomfort that comes with acute laminitis flare-ups.

Q2: How quickly does Bute injection take effect in horses?

Ans: A clinical response is generally seen within 24 hours of the first administration. If no meaningful improvement shows up after five days of treatment, the diagnosis and approach should be reviewed in full with a veterinarian before continuing.

Q3: Can Phenylbutazone injection be given intramuscularly in horses?

Ans: No. This product must only be delivered intravenously in horses. Giving it intramuscularly or under the skin can lead to severe tissue death and serious complications. The administration route set by your veterinarian must always be followed without deviation.

Q4: What are the risks of long-term Bute use in horses?

Ans: Extended use raises the risk of gastrointestinal ulcers, right dorsal colitis, and kidney strain. Horses that are dehydrated, very young, elderly, or already dealing with kidney or stomach issues face a higher chance of developing these complications during prolonged treatment.

Q5: Do I need a prescription for Phenylbutazone Injection for my horse?

Ans: Yes, this is a prescription-only medication. Federal law limits its use to the order of a licensed veterinarian. A valid prescription and an active veterinarian-client-patient relationship must both be in place before this product can be bought or administered to your horse.