Polyflex (ampicillin) Injection 25mg (200 ml)

Polyflex (Ampicillin) Injection 25 mg - Broad-Spectrum Antibiotic for Pets

Polyflex Injection is a broad-spectrum antibiotic formulated to combat a wide range of bacterial infections in animals. This veterinary-grade ampicillin injection is prescribed by veterinarians for its efficacy against respiratory, urinary, gastrointestinal, and systemic infections in animals including dogs, cats, cattle, and horses.

Designed to target bacteria susceptible to ampicillin, Polyflex is a go-to solution for infections that traditional penicillin therapies struggle to treat.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.

NOTE: For generic medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer.

What are the Benefits of Polyflex (Ampicillin) Injection?

Polyflex offers several significant advantages for treating bacterial infections in animals:

• Broad-Spectrum Activity: Targets multiple bacterial strains, including Escherichia coli, Staphylococcus spp., Pasteurella multocida, and more.
• Effective Across Species: Suitable for various animals, including dogs, cats, cattle, and horses.
• Fast-Acting Relief: Provides rapid symptom relief in acute infections like respiratory and urinary tract infections.
• Reliable for Severe Infections: Effective for infections often resistant to basic penicillin, making it ideal for harder-to-treat conditions.
• Veterinary-Approved Dosage Flexibility: Easily adjusted dosages based on the animal's condition and response.

What Are the Ingredients in Polyflex Injection?

Polyflex Injection’s active ingredient, ampicillin trihydrate, is a powerful antibiotic in the penicillin family, specifically formulated to target a range of bacterial infections in animals. Each vial contains the following components:

• Ampicillin Trihydrate: This is the primary active ingredient that disrupts bacterial cell wall synthesis, effectively killing susceptible bacteria.
• Sodium Citrate: Acts as a buffering agent to stabilize the pH level, ensuring the solution remains suitable for injection.
• Sterile Water for Injection (added upon reconstitution): Used to dissolve the ampicillin powder into an injectable solution. The water must be sterile to maintain the injection’s safety and effectiveness.

Polyflex is a dry-fill solution, meaning it must be mixed with sterile water before administration. Once reconstituted, the solution has a white to pale yellow appearance, signifying readiness for injection. This formulation ensures precise dosing and maintains stability for effective infection control in animals.

Always consult your veterinarian if you have concerns about any ingredient or potential allergies your pet may have to components within Polyflex Injection.

How to Use Polyflex Injection?

Dosage and Administration
Consult your veterinarian for exact dosing instructions. Below are general dosage guidelines:

• Dogs & Cats: Administer 3 mg per lb of body weight, twice daily, via subcutaneous or intramuscular injection.
• Cattle and Calves: Dosage ranges from 2 mg to 5 mg per lb of body weight, once daily by intramuscular injection. Treatment duration should not exceed 7 days.

Preparation of Injection
To reconstitute, add the appropriate amount of Sterile Water for Injection, shake well until the solution is uniform, and ensure the appearance is white to pale yellow. Label the vial with the date of reconstitution and note the concentration for accurate dosing.

What Conditions Does Polyflex Treat?

Polyflex is indicated for multiple infections caused by bacteria susceptible to ampicillin:

• Respiratory Tract Infections: Common in dogs, cats, and cattle, such as bronchopneumonia and bacterial pneumonia.
• Urinary Tract Infections: Effective for infections caused by Proteus mirabilis, Escherichia coli, and other bacteria.
• Gastrointestinal Infections: Used for infections due to Enterococcus spp., Staphylococcus spp., and E. coli.
• Systemic and Soft Tissue Infections: Effective for additional bacterial infections sensitive to ampicillin.

Are There Any Contraindications?

Animals with known allergies to penicillin, cephalosporins, or related antibiotics should not use Polyflex due to the risk of serious allergic reactions. Immediate veterinary consultation is recommended if any signs of allergic response occur.

What Are the Potential Side Effects of Polyflex?

Possible side effects may include:

• Allergic Reactions: Animals sensitive to penicillin may develop allergic responses, which can include skin irritation, swelling, or respiratory issues.
• Gastrointestinal Upset: Mild cases of nausea, vomiting, or diarrhea may occur.

If an adverse reaction is observed, discontinue use and seek veterinary advice promptly.

Important Safety Information and Residue Warnings

• For Cattle: Do not treat cattle for longer than 7 days. Milk from treated cows must not be used for food during treatment and for 48 hours post-treatment. Additionally, cattle cannot be slaughtered for food until 144 hours after the final treatment dose.
• Avoid Use in Food-Producing Animals Within Warning Period: Ensures no antibiotic residue remains in food sources, preserving food safety.

What Are the Storage Guidelines?

• Storage Temperature: Store vials at or below 25°C (77°F) with short-term allowance up to 30°C (86°F).
• Refrigeration After Reconstitution: Once mixed, keep refrigerated and use within three months of the first puncture.
• Avoid Freezing: Freezing the reconstituted solution may reduce its effectiveness.

Shipping & Returns 

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FAQs -Polyflex Ampicillin Antibiotic Injection for Dogs, Cats, Cattle

What is Polyflex Injection used for?

Polyflex Injection treats bacterial infections in animals, particularly those affecting the respiratory, urinary, and gastrointestinal systems. Its broad-spectrum antibiotic properties target bacteria resistant to traditional penicillins, making it highly effective in treating conditions like pneumonia, UTIs, and skin infections in dogs, cats, cattle, and horses.

How does Polyflex Injection work against bacterial infections?

Polyflex works by inhibiting bacterial cell wall synthesis, which weakens and kills bacteria. Its active ingredient, ampicillin, penetrates the bacteria, preventing them from forming new cells, which effectively stops the infection from spreading.

Can Polyflex Injection be used in combination with other antibiotics?

Yes, Polyflex can sometimes be used with other antibiotics, but only under veterinary guidance. Combining antibiotics can enhance effectiveness for severe or resistant infections, but improper use can cause adverse reactions or antibiotic resistance.

What precautions should I take before using Polyflex in my pet?

Ensure your pet isn’t allergic to penicillin or cephalosporins, as Polyflex can cause serious reactions in sensitive animals. Inform your veterinarian about any pre-existing conditions, medications, or previous reactions to antibiotics before administering Polyflex.

How quickly does Polyflex Injection start working?

Polyflex usually begins to reduce symptoms within 24 to 48 hours of administration, although the exact response time varies based on the severity of the infection and the pet’s immune response. Full recovery typically requires completing the prescribed course.

Can Polyflex be administered at home, or does a vet need to do it?

While Polyflex can technically be administered at home, it requires precise dosing and sterile injection techniques. Many veterinarians recommend it be administered by a professional or with veterinary guidance to ensure safe, effective use.

How should I monitor my pet for side effects after using Polyflex?

After administering Polyflex, monitor your pet for signs of allergic reactions, such as swelling, difficulty breathing, or skin irritation. Gastrointestinal symptoms like vomiting or diarrhea can also occur. If side effects are severe or persist, contact your vet immediately.

Is Polyflex safe for use in pregnant or nursing animals?

Polyflex should only be used in pregnant or nursing animals under strict veterinary supervision. While it’s generally safe, its use during pregnancy requires careful assessment to ensure there’s no risk to the mother or offspring.

How often can Polyflex be used in recurrent infections?

For recurrent infections, your vet may recommend an adjusted treatment plan or alternative antibiotics, as repeated use of Polyflex can lead to bacterial resistance. A comprehensive examination is necessary to determine the safest approach.

What should I do if my animal misses a dose of Polyflex?

If a dose is missed, administer it as soon as you remember, unless it’s close to the next scheduled dose. In that case, skip the missed dose to avoid overdosing. Never double up doses, as this can increase the risk of side effects. Always consult your veterinarian for further guidance.

Clinical Research:  

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=61be8261-ac3d-418a-a414-62c64d9eacc0