{"product_id":"decha-equidone-domperidone-gel-syringe-horses","title":"Equidone (domperidone) Gel 25 mL","description":"\u003cp\u003e\u003cimg src=\"https:\/\/hardypaw.com\/cdn\/shop\/files\/rx-map.webp\" alt=\"Rx Map\" border=\"0\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch2\u003ePrevents Fescue Toxicosis in Periparturient Mares Effectively\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eEQUIDONE® Gel is a prescription oral gel for animals that contains domperidone. It helps prevent fescue toxicosis in mares that are close to giving birth. The gel is given once a day before the expected foaling. It supports normal gestation, mammary development, and milk production in mares that have been exposed to infected fescue. The multi-dose syringe allows for accurate dosing based on the mare's weight. It is made by Dechra Veterinary Products and has been approved by the FDA.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevents toxicosis\u003c\/strong\u003e: Helps prevent fescue toxicosis in periparturient mares by counteracting dopamine effects caused by endophyte-infected fescue exposure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports lactation\u003c\/strong\u003e: Promotes mammary gland development and adequate milk production at foaling in mares affected by fescue alkaloids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImproves gestation timing\u003c\/strong\u003e: Assists in achieving a more normal gestation length and reduces complications associated with prolonged pregnancy due to toxicosis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEasy dosing\u003c\/strong\u003e: Multi-dose oral syringe with adjustable dial allows precise administration according to the mare's body weight requirements.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary approved\u003c\/strong\u003e: FDA-approved formulation with clinically demonstrated effectiveness when used at the recommended dose and timing before foaling.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eVariants\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eEQUIDONE® Gel 25 cc Single Syringe\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eDomperidone 110 mg per cc gel\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended-Dosage Chart\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 49.156%; height: 58px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"156\" style=\"width: 27.5408%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eBody Weight (lb)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.2608%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eBody Weight (kg)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"102\" style=\"width: 18.0005%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eDose (cc)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"169\" style=\"width: 25.2007%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eDomperidone (mg)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"156\" style=\"width: 27.5408%; height: 35.5966px;\"\u003e\n\u003cp\u003e550–660\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.2608%; height: 35.5966px;\"\u003e\n\u003cp\u003e250–300\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"102\" style=\"width: 18.0005%; height: 35.5966px;\"\u003e\n\u003cp\u003e3\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"169\" style=\"width: 25.2007%; height: 35.5966px;\"\u003e\n\u003cp\u003e330\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"156\" style=\"width: 27.5408%; height: 35.5966px;\"\u003e\n\u003cp\u003e661–880\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.2608%; height: 35.5966px;\"\u003e\n\u003cp\u003e301–400\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"102\" style=\"width: 18.0005%; height: 35.5966px;\"\u003e\n\u003cp\u003e4\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"169\" style=\"width: 25.2007%; height: 35.5966px;\"\u003e\n\u003cp\u003e440\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"156\" style=\"width: 27.5408%; height: 35.5966px;\"\u003e\n\u003cp\u003e881–1100\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.2608%; height: 35.5966px;\"\u003e\n\u003cp\u003e401–500\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"102\" style=\"width: 18.0005%; height: 35.5966px;\"\u003e\n\u003cp\u003e5\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"169\" style=\"width: 25.2007%; height: 35.5966px;\"\u003e\n\u003cp\u003e550\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"156\" style=\"width: 27.5408%; height: 35.5966px;\"\u003e\n\u003cp\u003e1101–1320\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.2608%; height: 35.5966px;\"\u003e\n\u003cp\u003e501–600\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"102\" style=\"width: 18.0005%; height: 35.5966px;\"\u003e\n\u003cp\u003e6\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"169\" style=\"width: 25.2007%; height: 35.5966px;\"\u003e\n\u003cp\u003e660\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003e\u003cstrong\u003eDirections for Use\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDetermine dose\u003c\/strong\u003e: Calculate the appropriate dose based on the mare's body weight using the dosing table before administering the oral gel product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSet syringe dial\u003c\/strong\u003e: Turn dial ring so edge nearest syringe tip aligns with dose marking for accurate administration measurement.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrepare the mouth\u003c\/strong\u003e: Ensure the horse's mouth is free of feed or obstructions before inserting the syringe nozzle through the interdental space.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdminister gel: \u003c\/strong\u003ePlace gel on the back of the tongue by fully pressing the plunger after inserting the nozzle into the horse's mouth.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdjust doses: \u003c\/strong\u003eRaise the dial setting progressively for later doses because the syringe holds multiple doses and keeps track of earlier administrations.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription required: \u003c\/strong\u003eFederal law limits this drug to licensed veterinarians, ensuring proper medical supervision during treatment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Information\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAccurate timing\u003c\/strong\u003e: Administration earlier than fifteen days before expected foaling may cause premature birth or low birth weight foals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding records\u003c\/strong\u003e: Accurate breeding and expected foaling dates are necessary to ensure safe and effective use in mares.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug interactions\u003c\/strong\u003e: Concurrent use with erythromycin or ketoconazole may significantly increase domperidone exposure due to metabolic inhibition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal blockage\u003c\/strong\u003e: Avoid use in horses with suspected gastrointestinal obstruction since domperidone stimulates gut motility and may worsen the condition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman safety\u003c\/strong\u003e: Pregnant or lactating women should handle with caution because systemic exposure may affect reproductive hormones.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePremature lactation: \u003c\/strong\u003eMilk dripping before foaling during treatment, and this is one of the most commonly reported reactions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePassive transfer failure:\u003c\/strong\u003e Foals might not get enough immunoglobulin, even if there is no visible colostrum loss from the treated mares.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePremature birth:\u003c\/strong\u003e Studies have shown early births with shorter gestation periods and lower birth weights for foals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFoal diarrhea: \u003c\/strong\u003eSome foals born to treated mares had mild diarrhea or loose stools that cleared up without treatment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom temperature\u003c\/strong\u003e: Store at controlled room temperature around 25°C with permitted excursions between 15°C and 30°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRecap syringe\u003c\/strong\u003e: Replace cap securely after each use to prevent contamination or accidental exposure and maintain product integrity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eShipping \u0026amp; Return\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eQ1: What is EQUIDONE® Gel used for in horses?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e EQUIDONE® Gel is prescribed to help prevent fescue toxicosis in mares around foaling. The domperidone formulation counteracts dopamine effects from infected fescue, supporting normal gestation, mammary development, and milk production when administered before the expected foaling date under veterinary supervision. Manufactured by Dechra Veterinary Products.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ2: When should EQUIDONE® Gel treatment be started?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Treatment is typically started 10 to 15 days prior to the mare’s expected foaling date. Accurate breeding records are essential because administering earlier than recommended may increase risks such as premature birth, low birth weight foals, or foal health complications.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ3: How long should EQUIDONE® Gel be given after foaling?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Post giving birth, if the mare doesn’t produce enough milk, then treatment can go on for up to five days. However, the exact duration should always be decided by a veterinarian, taking into account the mare's milk production and her general health.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ4: Do foals from treated mares need any testing?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e All foals from mares treated with EQUIDONE® Gel should have their serum immunoglobulin G levels tested to ensure their health. Passive transfer failure can happen even if there is no visible colostrum leakage, so it’s a good idea to have veterinary monitoring to ensure enough immune protection.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ5: Is EQUIDONE® Gel available without a prescription?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No, federal law in the United States restricts this medication to use only by or under the direction of a licensed veterinarian. Having a vet involved ensures that the dosing is correct, the timing is appropriate for foaling, and that any potential complications or side effects are monitored closely.\u003c\/p\u003e","brand":"Dechra","offers":[{"title":"Default Title","offer_id":43681960329377,"sku":"Equ-025S","price":470.0,"currency_code":"RON","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/equidone-domperidone-gel-25-ml-horse-health-wellness-926.jpg?v=1778542521","url":"https:\/\/hardypaw.com\/en-ro\/products\/decha-equidone-domperidone-gel-syringe-horses","provider":"HardyPaw","version":"1.0","type":"link"}