{"product_id":"dechra-sporimune-cyclosporine-capsules-usp-modified-25mg","title":"Sporimune (Cyclosporine) USP Modified, 25mg (15 capsules)","description":"\u003cp align=\"center\"\u003e\u003cimg width=\"700\" alt=\"RX MAP\" class=\"img-responsive\" src=\"https:\/\/hardypaw.com\/cdn\/shop\/files\/rx-map.webp\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch2\u003eHelps Manage Atopic Dermatitis Symptoms in Dogs\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Description \u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSporimune (Cyclosporine) USP Modified 25 mg is an oral medication that helps control atopic dermatitis in dogs weighing at least 4 lbs. It targets immune responses linked to allergic skin problems, which helps reduce itching and inflammation. The modified microemulsion formulation ensures consistent absorption, making it suitable for long-term management of chronic skin conditions under veterinary care. Manufactured for Dechra Veterinary Products.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eBenefits \u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune Modulation:\u003c\/strong\u003e Helps suppress T cell activation and interleukin-2 production involved in allergic skin inflammation in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReduces Itching:\u003c\/strong\u003e Demonstrated improvement in pruritus scores in clinical studies of dogs with atopic dermatitis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon Steroidal:\u003c\/strong\u003e Provides an alternative to corticosteroids or antihistamines for managing chronic allergic skin disease.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlexible Dosing:\u003c\/strong\u003e Daily dosing can be tapered to less frequent administration once clinical improvement is achieved.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConsistent Absorption:\u003c\/strong\u003e Modified microemulsion formulation enhances bioavailability in aqueous environments after oral administration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients \u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eCyclosporine 25 mg per capsule\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow to Use \u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended Dosage Chart \u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 42.3882%; height: 45px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 55.1989px;\"\u003e\n\u003ctd width=\"212\" style=\"width: 37.6211%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eDog Body Weight (lbs)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"209\" style=\"width: 37.0811%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eDog Body Weight (kg)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"196\" style=\"width: 24.8407%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dose\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"212\" style=\"width: 37.6211%; height: 35.5966px;\"\u003e\n\u003cp\u003e9.1 – 16 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"209\" style=\"width: 37.0811%; height: 35.5966px;\"\u003e\n\u003cp\u003e4 – 7.9 kg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"196\" style=\"width: 24.8407%; height: 35.5966px;\"\u003e\n\u003cp\u003e1 × 25 mg capsule\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003e\u003cstrong\u003eDosage \u0026amp; Administration Instructions \u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary Prescription:\u003c\/strong\u003e This medication is for use only by a licensed veterinarian or as instructed by one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInitial Dosing: \u003c\/strong\u003eThe recommended starting dose is 5 mg per kg of body weight once a day for the first 30 days.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMaintenance Adjustment:\u003c\/strong\u003e After improvement, the dosage may be changed to every other day or twice a week as directed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMeal Timing:\u003c\/strong\u003e Administer at least one hour before feeding or two hours after meals for optimal absorption.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMissed Dose:\u003c\/strong\u003e In case a dose is missed, give the next dose as soon as possible without doubling the frequency.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCapsule Handling:\u003c\/strong\u003e Capsules should not be opened or broken, and hands should be washed after administration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Information \u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions \u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAge Restrictions:\u003c\/strong\u003e Safety has not been established in dogs younger than six months or weighing less than four pounds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Warning: \u003c\/strong\u003eNot suitable for breeding dogs, pregnant animals, or nursing females as there is not enough safety data.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiabetes Risk:\u003c\/strong\u003e Use it with caution in dogs with diabetes mellitus, as cyclosporine may raise blood glucose levels.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions: \u003c\/strong\u003eMedications that affect the cytochrome P450 enzyme system can significantly change cyclosporine blood levels.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfection Susceptibility: \u003c\/strong\u003eThe immunosuppressive effects may make dogs more prone to infections or worsen existing hidden conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRenal Caution: \u003c\/strong\u003eUse it carefully in dogs with kidney problems since safety in those with renal insufficiency is not known.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects \u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Signs:\u003c\/strong\u003e Vomiting and diarrhea were the most commonly reported adverse reactions during clinical field studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy Effects:\u003c\/strong\u003e Some dogs experienced lethargy, decreased appetite, or behavioral changes while receiving cyclosporine treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGum Changes:\u003c\/strong\u003e Gingival hyperplasia or swollen gums may occur, but often regress after dosage reduction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInfection Risk:\u003c\/strong\u003e Persistent ear infections or urinary tract infections have been observed during treatment in some dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurologic Signs:\u003c\/strong\u003e Rare neurologic effects such as tremors or seizures have been reported during cyclosporine administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic Changes:\u003c\/strong\u003e Elevated blood glucose or development of diabetes mellitus has been reported in some treated dogs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Store Sporimune capsules at 68°F-77°F or 20°C to 25°C to maintain stability and effectiveness. \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOriginal Packaging:\u003c\/strong\u003e Keep the capsules in their original unit-dose blister packaging to protect the medication from environmental exposure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecure Placement:\u003c\/strong\u003e Store the medication in a secure place away from children and pets to avoid accidental exposure.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\n\u003cstrong\u003eShipping \u0026amp; Return\u003c\/strong\u003e \u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details. \u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.  \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eQ1: What is Sporimune used for in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns: \u003c\/strong\u003eSporimune (cyclosporine capsules) is used to control atopic dermatitis in dogs that weigh at least 4 lbs. It helps by adjusting the immune system to lower inflammation and itching tied to allergic skin disease. It is not a steroid or antihistamine.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ2: How long does Sporimune take to work in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Clinical studies showed that itching and \u003ca href=\"\/en-ro\/blogs\/news\/dog-diseases-treatments\" title=\"Dog diseases \u0026amp; treatments - a to z guide for pet owners\" aria-label=\"Dog diseases \u0026amp; treatments - a to z guide for pet owners\"\u003eskin lesion\u003c\/a\u003e severity improved within the first 30 days of treatment at the recommended dose. Some dogs may need continued therapy and changes in dosage to reach the best long-term control of symptoms, as directed by a veterinarian.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ3: How should Sporimune be given to dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Sporimune should be given at least one hour before meals or two hours after meals to support proper absorption. Do not open or break the capsules. Always follow your veterinarian’s dosing instructions and do not give doses more often than recommended.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ4: Can Sporimune dosage be reduced over time?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes, after the initial daily treatment period, the dosing frequency may be gradually reduced to every other day or twice a week once clinical improvement is seen. The goal is to keep the desired therapeutic effect while using the lowest effective dosing frequency decided by a veterinarian.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ5: What are the common side effects of Sporimune in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The most commonly reported side effects are vomiting and diarrhea. Other possible reactions include lethargy, gingival hyperplasia, infections like otitis externa, and decreased appetite. Many mild gastrointestinal signs may go away with ongoing treatment or short-term dose changes under veterinary supervision.\u003c\/p\u003e","brand":"Dechra","offers":[{"title":"Default Title","offer_id":43864700354721,"sku":"SPOR25-15","price":161.0,"currency_code":"RON","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/sporimune-cyclosporine-usp-modified-25mg-15-capsules-712.png?v=1777918001","url":"https:\/\/hardypaw.com\/en-ro\/products\/dechra-sporimune-cyclosporine-capsules-usp-modified-25mg","provider":"HardyPaw","version":"1.0","type":"link"}