{"product_id":"dechra-vetoryl-capsules-for-dogs-5mg","title":"Vetoryl Capsules (Trilostane) for Dogs, 5mg","description":"\u003ch2\u003eOnce-Daily Trilostane Capsule for Cushing's Disease in Dogs\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eVetoryl Capsules (Trilostane) 5 mg is an FDA-approved, prescription-only oral treatment for Cushing's disease in dogs. Each capsule holds 5 mg of trilostane, a synthetic steroid analogue that brings cortisol production in the adrenal cortex under control. Given once daily with food, it manages both pituitary-dependent and adrenal-dependent forms of the condition and is the smallest strength in the range, making it the natural starting point for toy breeds and very small dogs.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Cushing's Disease:\u003c\/strong\u003e Effective for both pituitary-dependent and adrenal-dependent hyperadrenocorticism, the two most frequently diagnosed forms of Cushing's disease in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargets the Root Cause:\u003c\/strong\u003e By reversibly blocking 3-beta-hydroxysteroid dehydrogenase in the adrenal cortex, trilostane reduces the overproduction of cortisol right at its source.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Proven Results:\u003c\/strong\u003e Most dogs in clinical field studies showed measurable improvement in thirst, urination, and panting within the first 14 days of therapy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce-Daily Convenience:\u003c\/strong\u003e One oral dose each day is all that is needed, making it simple to build into a long-term daily care routine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdeal Starter Strength:\u003c\/strong\u003e As the smallest available Vetoryl dose, the 5 mg capsule is the go-to choice for toy breeds and very small dogs beginning trilostane therapy for the first time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReversible Suppression:\u003c\/strong\u003e Trilostane's cortisol-reducing effect can be reversed, so your veterinarian can safely adjust or stop treatment as your dog's needs change over time.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 45.0597%; height: 5px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 39.4211%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 60.1217%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 39.4211%; height: 19.6023px;\"\u003eTrilostane\u003c\/td\u003e\n\u003ctd style=\"width: 60.1217%; height: 19.6023px;\"\u003e5 mg per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eOther Ingredients\u003c\/h4\u003e\n\u003cp\u003eGelatin capsule shell, Lactose, Magnesium Stearate, Colloidal Silicon Dioxide\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e US Federal law limits this medication to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Dogs Only:\u003c\/strong\u003e This medication is for oral use in dogs only and must never be given to humans or other animal species.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStarting Dose:\u003c\/strong\u003e Your veterinarian will work out the appropriate starting dose for your dog based on body weight and individual health needs before prescribing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGive With Food:\u003c\/strong\u003e Give one dose each morning with food to support proper absorption and reduce the likelihood of digestive upset.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the Capsule Whole:\u003c\/strong\u003e Never break open, empty, or divide the capsule; it should always be given intact as your vet or pharmacist dispensed it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEarly Check-In:\u003c\/strong\u003e Plan for a vet visit around 10 to 14 days after starting, where an ACTH stimulation test and full biochemistry panel will be carried out.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustments:\u003c\/strong\u003e Changes to the dose are made based on test results and how your dog is doing clinically; never adjust the dose without your veterinarian's direction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWatch for Warning Signs:\u003c\/strong\u003e If your dog vomits, has diarrhea, seems unusually tired, loses interest in food, becomes weak, or collapses, stop the medication right away and call your vet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWash Hands After Handling:\u003c\/strong\u003e Wash your hands thoroughly with soap and water each time you handle the capsules.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity:\u003c\/strong\u003e Do not use in dogs with a known allergic reaction or sensitivity to trilostane.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver or Kidney Disease:\u003c\/strong\u003e Dogs with liver or kidney problems are not suitable candidates; both organ systems should be evaluated before treatment starts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pregnant Dogs:\u003c\/strong\u003e Trilostane has been associated with birth defects and early pregnancy loss in animal studies; it must never be used in pregnant dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnant Handlers:\u003c\/strong\u003e Anyone who is pregnant or trying to conceive should avoid all contact with these capsules given the known teratogenic risk of trilostane.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdrenal Over-Suppression:\u003c\/strong\u003e Addison's disease can develop regardless of the dose used; some dogs need months to recover normal adrenal function and some may not recover fully at all.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeart Medications:\u003c\/strong\u003e Take extra care if your dog is on any heart medication; inform your vet of everything your dog is currently taking before beginning treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevious Mitotane Use:\u003c\/strong\u003e At least one full month must pass after stopping mitotane, and ACTH levels must be back to normal, before Vetoryl therapy can begin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactating and Breeding Males:\u003c\/strong\u003e The safety profile in nursing females and males used for breeding has not been established; always check with your vet before using in these animals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnorexia and Vomiting:\u003c\/strong\u003e A drop in appetite and vomiting are the most commonly reported reactions; if your dog experiences either, pause the medication and get in touch with your vet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy and Weakness:\u003c\/strong\u003e Tiredness, reduced interest in activity, and general physical weakness have been consistently reported across clinical and post-market data.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Loose or watery stools have been noted in some dogs; keep an eye on bowel habits and report anything unusual to your veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElevated Liver Enzymes:\u003c\/strong\u003e Some dogs show rises in liver enzyme levels; this is another reason why regular bloodwork matters throughout treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalances:\u003c\/strong\u003e Changes in potassium and sodium balance can signal that adrenal suppression has gone too far and needs to be addressed quickly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Adverse Events:\u003c\/strong\u003e Rare but serious outcomes including kidney failure and Addison's disease have in some cases been fatal; get veterinary help immediately if your dog suddenly worsens or collapses.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Keep at around 25°C (77°F), away from moisture and direct sunlight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away from Children and Pets:\u003c\/strong\u003e Store this prescription medication somewhere children and other animals simply cannot get to.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What condition does Vetoryl (Trilostane) 5 mg treat in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Vetoryl 5 mg treats hyperadrenocorticism, more commonly known as Cushing's disease, in dogs. It is effective for both the pituitary-dependent type, which is the most frequently seen form, and the adrenal-dependent type, where excess cortisol stems from a growth on the adrenal gland.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does trilostane in Vetoryl work to control Cushing's disease?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Trilostane reversibly blocks 3-beta-hydroxysteroid dehydrogenase, the enzyme that drives cortisol production in the adrenal cortex. By interrupting this step, it reduces the amount of cortisol the body produces, easing the hormonal overload that causes the symptoms of Cushing's disease in dogs.\u003c\/p\u003e\n\u003ch3\u003eQ3: How quickly does Vetoryl 5 mg start working in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Most dogs in clinical studies showed clear signs of improvement within 14 days of starting Vetoryl. Owners typically noticed less thirst, fewer bathroom trips, and reduced panting fairly early on. A follow-up ACTH stimulation test is usually booked for the 10 to 14 day mark to check how the dose is performing.\u003c\/p\u003e\n\u003ch3\u003eQ4: Why does my dog need regular testing while on Vetoryl 5 mg?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Regular testing matters because even a low dose can sometimes suppress adrenal function more than intended, leading to Addison's disease. Routine ACTH stimulation tests and biochemistry panels keep cortisol within a safe range and help your vet catch any concerning shifts before they become serious.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is Vetoryl (Trilostane) 5 mg a cure for Cushing's disease in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No. Vetoryl controls the condition by lowering cortisol production but does not remove the underlying cause. When treatment stops, cortisol levels rise again and symptoms return, which is why the vast majority of dogs with Cushing's disease remain on this medication for life.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\" title=\"Https:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\" aria-label=\"Visit a webpage about Https:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\"\u003ehttps:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5855282\/\" title=\"Update on the use of trilostane in dogs - pmc\" aria-label=\"Visit a webpage about Update on the use of trilostane in dogs - pmc\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5855282\/\u003c\/a\u003e\u003c\/p\u003e","brand":"Dechra","offers":[{"title":"30 Capsules","offer_id":44488063647905,"sku":"VET-005","price":348.0,"currency_code":"RON","in_stock":true},{"title":"60 Capsules","offer_id":44488063680673,"sku":"VET-005-60","price":695.0,"currency_code":"RON","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/vetoryl-capsules-trilostane-for-dogs-5mg-pet-medicine-496.jpg?v=1778103585","url":"https:\/\/hardypaw.com\/en-ro\/products\/dechra-vetoryl-capsules-for-dogs-5mg","provider":"HardyPaw","version":"1.0","type":"link"}