Ketofen (ketoprofen) Injectable Solution for Horses

NSAID Injectable Solution for Musculoskeletal Pain Relief in Horses

Product Description

Ketofen (Ketoprofen) Injectable Solution 100 mg/mL is an FDA-approved prescription non-narcotic NSAID for intravenous use in horses only. Each mL has 100 mg ketoprofen with L-Arginine 70 mg, citric acid for pH balancing, and 0.025 g benzyl alcohol as a preservative. It comes in a multi-dose bottle for treating inflammation and pain linked to musculoskeletal disorders in horses.

Benefits

• Musculoskeletal Pain Relief: Targets and reduces inflammation and pain tied to musculoskeletal disorders in horses with each intravenous dose.
• Fast Onset of Action: Anti-inflammatory activity gets going within two hours of a single intravenous dose in horses.
• Peak Response: Anti-inflammatory effects hit their peak at 12 hours and remain detectable a full 24 hours after each dose.
• Non-Narcotic Formula: Ketoprofen is a propionic acid class NSAID that delivers solid pain relief without any of the risks tied to narcotic drugs.
• Analgesic and Antipyretic: Alongside fighting inflammation, this injectable also provides pain relief and fever-reducing effects in horses.
• Wide Safety Margin: Safety studies showed horses handled a dose 5X higher than recommended across 15 consecutive days without any toxic effects.

Ingredients

Active Ingredients

Ketoprofen: 100 mg per mL

Inactive Ingredients

L-Arginine 70 mg/mL, citric acid (to adjust pH), benzyl alcohol 0.025 g/mL (preservative)

How to Use

Dosage and Administration Instructions

• Prescription Required: Federal law restricts Ketofen to use by or on the order of a licensed veterinarian only.
• Recommended Dose: Give 1 mg per lb (1 mL per 100 lbs) of body weight by intravenous injection once daily.
• Intravenous Route Only: Give by IV injection only; intra-arterial injection must be avoided to prevent serious local reactions.
• Treatment Duration: Can be repeated once daily for up to 5 consecutive days; never go beyond the approved five-day period.
• Multi-Dose Vial Use: Use within 28 days of first opening; always use aseptic technique when drawing each dose from the vial.
• Monitor Drug Compatibility: No drug interaction studies have been done; watch closely for compatibility issues in horses on other therapies.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Horses Only: Ketofen is cleared for IV use in horses only and must never be given to any other animal species.
• Not for Breeding Animals: Ketoprofen's effects on fertility, pregnancy, and fetal health are unknown; keep away from all breeding animals.
• Avoid Concurrent NSAIDs: Using other NSAIDs or corticosteroids at the same time raises the risk of gut ulceration and must be avoided.
• Hypersensitivity History: Never use in any horse that has had a prior reaction to ketoprofen or other propionic acid class NSAIDs.
• Not for Human Consumption: Do not use in horses going into the food supply as Ketofen is not cleared for food-animal use.
• GI Risk Monitoring: Watch for signs of gut ulceration or perforation throughout the course, especially at higher doses or longer use.

Possible Side Effects

• No Significant Side Effects: No meaningful side effects were seen in horses treated at the recommended dose during investigational studies.
• Overdose Risk Laminitis: At 15 times the recommended dose for five days, one of two horses developed severe laminitis in safety testing.
• Severe Overdose Effects: At 25 times the dose, horses showed poor appetite, depression, jaundice, gut swelling, and organ inflammation.
• GI Ulceration Potential: Like all NSAIDs, Ketofen can cause gut ulceration or perforation; keep a close eye on horses throughout treatment.

Storage Information

• Room Temperature Storage: Keep at 20-25°C (68-77°F); brief periods between 15-30°C (59-86°F) will not affect the product's stability.
• Do Not Freeze: Never freeze Ketofen as low temperatures can break down the sterile solution and make it unsafe to use.
• 28-Day Use Window: Throw out any unused solution 28 days after the vial was first opened to keep the product sterile and safe.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Ketofen ketoprofen injection used for in horses?

Ans: Ketofen (ketoprofen) 100 mg/mL is an FDA-approved prescription NSAID for IV use in horses that targets inflammation and pain from musculoskeletal disorders. Anti-inflammatory activity kicks in within two hours of the first dose and peaks at the 12-hour mark after each injection.

Q2: What is the correct dose and duration of Ketofen equine NSAID injection?

Ans: Each horse gets 1 mg per lb (1 mL per 100 lbs) of body weight by IV injection once a day. This can continue for up to five days in a row, but the five-day limit must not be crossed without a fresh assessment from the treating veterinarian.

Q3: Can Ketofen horse anti-inflammatory injection be used with other NSAIDs or steroids?

Ans: No, pairing Ketofen with other NSAIDs or corticosteroids should be avoided or watched very closely. NSAIDs as a group carry a real risk of gut ulceration and perforation, and no compatibility studies have been done to confirm how Ketofen interacts with other drugs.

Q4: Is Ketofen ketoprofen IV solution safe for breeding mares or pregnant horses?

Ans: No, Ketofen must not be given to any breeding animal. The impact of ketoprofen on fertility, pregnancy outcomes, and fetal health in horses has not been studied, making it unsafe for pregnant mares, breeding mares, and any stallion used for reproduction purposes.

Q5: How long can an opened multi-dose vial of Ketofen equine pain injection be used?

Ans: After the vial is first punctured, it must be used up within 28 days. Every dose drawn out should be done using a clean sterile needle and proper aseptic technique throughout. Any leftover solution sitting past that 28-day point needs to be thrown out right away.