{"product_id":"promace-acepromazine-injection","title":"PromAce (acepromazine) 10mg\/ml Injection, 50ml vial","description":"\u003ch2\u003eMulti-Species Phenothiazine Injectable Tranquilizer and Preanesthetic for Dogs, Cats, and Horses\u003c\/h2\u003e\n\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003ePromAce (Acepromazine Maleate) Injectable Solution 10 mg\/mL is an FDA-approved prescription phenothiazine neuroleptic for intravenous, intramuscular, or subcutaneous use in dogs, cats, and horses, supplied in a 50 mL multi-dose vial. Each mL contains 10 mg acepromazine maleate, 0.36% sodium citrate, 0.075% citric acid, 1% benzyl alcohol as preservative, and water for injection. It acts rapidly to produce sedation, muscular relaxation, and reduction in spontaneous activity through central nervous system depression, without a hypnotic effect. Indicated for tranquilization and as a preanesthetic agent across all three species. Unlike the tablet form, the injectable covers dogs, cats, and horses in a single formulation.\u003c\/p\u003e\n\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eThree-Species Coverage:\u003c\/strong\u003e A single vial provides injectable tranquilization for dogs, cats, and horses — the only PromAce formulation approved across all three species.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eThree Administration Routes:\u003c\/strong\u003e Can be given IV, IM, or SC depending on the clinical situation and species, giving the veterinarian flexible delivery options at the point of care.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eEffective Equine Procedure Aid:\u003c\/strong\u003e Particularly useful in horses when combined with local anesthesia for firing, castration, neurectomy, skin tumor removal, ocular surgery, and cast application.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFacilitates Loading and Transport in Horses:\u003c\/strong\u003e Helps manage fractious horses during examination, treatment, loading, and transportation where oral administration is not practical.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eLowers Anesthetic Requirements Across Species:\u003c\/strong\u003e As a preanesthetic in dogs, cats, and horses, acepromazine reduces total general anesthetic dose needed and supports smoother induction.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eRapid Onset Without Hypnosis:\u003c\/strong\u003e Acts quickly to calm and sedate without producing a hypnotic state, keeping the animal responsive throughout the procedure.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003e50 mL Multi-Dose Vial:\u003c\/strong\u003e The 50 mL format supports repeated veterinary clinic use across multiple patients, making it practical for practice inventory and large animal field work.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eAcepromazine Maleate: 10 mg per mL\u003c\/p\u003e\n\u003ch4\u003eInactive Ingredients\u003c\/h4\u003e\n\u003cp\u003eSodium citrate 0.36%, citric acid 0.075%, benzyl alcohol 1% (preservative), water for injection\u003c\/p\u003e\n\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage and Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e Federal law restricts PromAce Injectable to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eIndividualize Every Dose:\u003c\/strong\u003e The dose should be tailored to the degree of tranquilization required; as a general rule, the mg\/lb requirement decreases as the animal's body weight increases.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDog Dose (IV\/IM\/SC):\u003c\/strong\u003e Give 0.25 to 0.5 mg\/lb of body weight; IV doses must be administered slowly with at least 15 minutes allowed for full effect to develop.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCat Dose (IV\/IM\/SC):\u003c\/strong\u003e Give 0.5 to 1 mg\/lb of body weight; cats require a relatively higher dose per pound than dogs to achieve the same level of sedation.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHorse Dose (IV\/IM\/SC):\u003c\/strong\u003e Give 2 to 4 mg per 100 lb of body weight; limit the dose to the minimum needed due to the risk of penile paralysis in male horses.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eIV Administration — Allow 15 Minutes:\u003c\/strong\u003e After IV injection across all species, wait a full 15 minutes before assessing full sedative effect or making any dose adjustments.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSmaller Doses for Sensitive Patients:\u003c\/strong\u003e Reduce the dose and proceed with extra caution in animals under stress, cardiac disease, hypovolemia, or shock conditions.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAdditive CNS Effects Require Anesthetic Dose Reduction:\u003c\/strong\u003e When used as a preanesthetic, reduce the dose of general anesthetics accordingly as acepromazine potentiates CNS depression.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eOrganophosphate Contraindication:\u003c\/strong\u003e Phenothiazines potentiate organophosphate toxicity; never use PromAce Injectable alongside organophosphate dewormers, ectoparasiticides, or flea collars in any species.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eProcaine Hydrochloride Contraindication:\u003c\/strong\u003e Do not use PromAce Injectable alongside procaine hydrochloride; acepromazine potentiates the activity of this local anesthetic.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eEpinephrine Contraindicated:\u003c\/strong\u003e Do not administer epinephrine to acepromazine-treated animals; the alpha-blockade caused by phenothiazines leads to a paradoxical, potentially fatal blood pressure drop.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePenile Paralysis Risk in Male Horses:\u003c\/strong\u003e Acepromazine can cause irreversible paralysis of the retractor penis muscle in castrated and uncastrated male horses; use only the minimum dose needed and warn owners of this risk.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eIntracarotid Injection in Horses is Potentially Fatal:\u003c\/strong\u003e Accidental intracarotid injection in horses can cause clinical signs ranging from disorientation and convulsions through to death; exercise extreme care during equine IV administration.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNot for Horses Intended for Human Consumption:\u003c\/strong\u003e Do not use PromAce Injectable in horses destined for the human food supply.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNo Reversal Agent Available:\u003c\/strong\u003e There is no pharmacological reversal agent for acepromazine across any species; all treated animals must be monitored throughout the full duration of sedation.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eKeep Out of Reach:\u003c\/strong\u003e Store in a secured location away from children and all animals to prevent any accidental access to this injectable CNS-active agent.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eProlonged CNS Depression or Motor Restlessness:\u003c\/strong\u003e Excessive doses or use in sensitive animals can cause prolonged depression or paradoxical motor restlessness instead of the intended calming effect.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eIdiosyncratic Behavioral Reactions in Dogs and Cats:\u003c\/strong\u003e Rare but serious reactions including aggression, biting or chewing, and nervousness have been reported following parenteral acepromazine administration.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePenile Protrusion in Male Horses:\u003c\/strong\u003e Reversible protrusion of the penis is a normal clinical sign during equine acepromazine narcosis; however, irreversible retractor muscle paralysis, though rare, has been reported.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eIntracarotid Reaction in Horses:\u003c\/strong\u003e Signs from accidental intracarotid injection range from disorientation and convulsive seizures to death in horses; this underscores the importance of confirmed venous placement before equine IV injection.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eControlled Room Temperature:\u003c\/strong\u003e Store at 20-25°C (68-77°F); excursions between 15-30°C (59-86°F) are permitted without affecting injectable solution stability or potency.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eKeep Out of Reach:\u003c\/strong\u003e Store in a locked, secure location away from children and all animals at all times.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\n\u003ch3\u003eQ1: What animals can PromAce injectable acepromazine be used in?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PromAce Injectable 10 mg\/mL is FDA-approved for intravenous, intramuscular, or subcutaneous use in dogs, cats, and horses. Unlike the PromAce tablet form, which is approved for dogs only, the injectable solution covers all three species in a single 50 mL multi-dose vial formulation.\u003c\/p\u003e\n\n\u003ch3\u003eQ2: What are the correct doses of PromAce acepromazine injection for dogs, cats, and horses?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e For dogs, give 0.25-0.5 mg\/lb by IV, IM, or SC. For cats, give 0.5-1 mg\/lb by IV, IM, or SC. For horses, give 2-4 mg per 100 lb by IV, IM, or SC. IV doses must be given slowly across all species, with a minimum 15-minute wait before assessing full effect. Dosages decrease per lb as body weight increases.\u003c\/p\u003e\n\n\u003ch3\u003eQ3: What is the penile paralysis risk in male horses given PromAce acepromazine injection?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Acepromazine can cause irreversible paralysis of the retractor penis muscle in both castrated and uncastrated male horses, which is distinct from the reversible penile protrusion expected during normal acepromazine narcosis. The two cannot be differentiated at the time of tranquilization; therefore, only the minimum dose needed for the desired effect should be used in male horses.\u003c\/p\u003e\n\n\u003ch3\u003eQ4: Why is intracarotid injection of PromAce so dangerous in horses?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Accidental intracarotid injection of acepromazine in horses can produce severe neurological reactions ranging from disorientation and convulsive seizures all the way through to death. This makes confirming proper venous placement critical before any equine intravenous injection; when there is any doubt about the injection site, the IM route is the safer alternative.\u003c\/p\u003e\n\n\u003ch3\u003eQ5: Why is the cat dose of PromAce injectable higher per pound than the dog dose?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Cats typically require a higher dose on a mg\/lb basis (0.5–1 mg\/lb) than dogs (0.25–0.5 mg\/lb), due to species-related differences in drug metabolism and receptor sensitivity to phenothiazines. In general across species, the required mg\/lb dose tends to decrease as body weight increases, meaning smaller cats often need a greater dose per pound compared with larger dogs.\u003c\/p\u003e","brand":"Boehringer Ingelheim","offers":[{"title":"Default Title","offer_id":41753968935073,"sku":"078935734","price":186.0,"currency_code":"RON","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/promace-acepromazine-10mg-ml-injection-50ml-vial-pet-medicine-518.jpg?v=1778180822","url":"https:\/\/hardypaw.com\/en-ro\/products\/promace-acepromazine-injection","provider":"HardyPaw","version":"1.0","type":"link"}