{"product_id":"simparica-flea-tick-chewables-large-dogs-brown-box","title":"Simparica for Large Dogs 88.1-132 lbs","description":"\u003ch2\u003eSimparica 120mg Monthly Chew for Complete Flea and Tick Defense in Extra-Large Dogs\u003c\/h2\u003e\n\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eSimparica (sarolaner) 120 mg is a prescription-strength, pork liver-flavored monthly chewable tablet specially formulated for extra-large dogs weighing 88.1 to 132 lbs. Powered by sarolaner, an isoxazoline-class insecticide and acaricide, it targets the nervous system of parasites to deliver fast, sustained protection. Fleas start dying off within 3 hours and ticks within 8 hours, with that level of protection holding steady without any drop-off right through the full 35 days.\u003c\/p\u003e\n\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eRapid Flea Elimination:\u003c\/strong\u003e Adult fleas begin dying off within just 3 hours of the first dose, bringing quick relief to large breeds dealing with active infestations.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eTick Control Within 8 Hours:\u003c\/strong\u003e All six controlled tick species are tackled within 8 hours, keeping outdoor and active large dogs well covered against tick threats.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSix-Tick Species Coverage:\u003c\/strong\u003e Kills Lone Star, Gulf Coast, American Dog, Black-legged, Brown Dog, and Asian Longhorned ticks with a single monthly dose.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDeer Tick Kill in 12 Hours:\u003c\/strong\u003e Shown to eliminate over 98% of existing deer tick infestations within 12 hours, well before Lyme disease transmission typically occurs.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFDA-Approved Lyme Prevention:\u003c\/strong\u003e Approved to block Borrelia burgdorferi infections by killing deer ticks, providing an important layer of disease prevention for large dogs.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eOral Waterproof Protection:\u003c\/strong\u003e As an oral treatment, bathing and swimming do not reduce its effectiveness, making it ideal for large, active, and water-loving breeds.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSustained 35-Day Potency:\u003c\/strong\u003e Unlike some treatments that weaken over time, Simparica maintains full effectiveness right through to day 35 without any drop in potency.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eSarolaner 120 mg per tablet\u003c\/p\u003e\n\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePrescription Requirement:\u003c\/strong\u003e Simparica is federally restricted to use by or on the order of a licensed veterinarian; always have a valid prescription before purchasing or administering.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCorrect Dose for Extra-Large Dogs:\u003c\/strong\u003e Administer one 120 mg chewable tablet orally once every 28 to 30 days to dogs weighing between 88.1 and 132 lbs.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFlexible Feeding Options:\u003c\/strong\u003e Offer the chew by hand, mixed into food, or like a standard oral tablet; Simparica can be given with or without food.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eConfirm Complete Consumption:\u003c\/strong\u003e Observe your dog for a few minutes after dosing to verify the entire tablet has been swallowed and no portion has been dropped or refused.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDogs Over 132 lbs:\u003c\/strong\u003e For dogs exceeding 132 lbs, administer an appropriate combination of Simparica tablets to cover the dog's total body weight as directed by your veterinarian.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eMissed Dose Protocol:\u003c\/strong\u003e On a missed dose, administer it right away and simply carry on with the usual monthly dosing from that point.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eYear-Round Monthly Use:\u003c\/strong\u003e Begin treatment at any time of year and continue every 30 days without interruption for reliable, unbroken flea and tick protection.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAge Restriction:\u003c\/strong\u003e Simparica is only approved for dogs 6 months of age and older; do not use in puppies younger than this regardless of body weight.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSeizure and Neurological History:\u003c\/strong\u003e Use with extra caution in dogs with a known history of seizures or neurological disorders and only under close veterinary supervision.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eReproductive Use Not Evaluated:\u003c\/strong\u003e How this product affects breeding, pregnant, or nursing dogs is still unknown, so always check with your vet beforehand.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eStrictly for Dogs Only:\u003c\/strong\u003e Simparica is formulated exclusively for dogs; it must never be administered to cats or any other animal species under any circumstances.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePrevent Accidental Ingestion:\u003c\/strong\u003e Keep this product tucked away somewhere all pets cannot reach, as accidental ingestion or overdose remains a real risk.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eChildren Must Not Access:\u003c\/strong\u003e Keep Simparica and all veterinary medications completely out of reach of children at all times.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eVomiting:\u003c\/strong\u003e The most frequently reported adverse reaction in clinical trials; typically mild and short-lived following administration of the monthly dose.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Loose stools, occasionally with blood, have been noted in a small percentage of dogs after receiving Simparica during clinical studies.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eLethargy:\u003c\/strong\u003e Some dogs may temporarily appear tired or less active for a short period following each monthly dose of Simparica.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eTremors and Unsteadiness:\u003c\/strong\u003e Muscle tremors and ataxia are reported post-approval adverse events; contact your veterinarian promptly if these signs appear after dosing.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSeizures:\u003c\/strong\u003e Seizures have been reported in dogs on isoxazoline-class products, including those with no prior seizure history; seek immediate veterinary attention if this occurs.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eReduced Appetite and Hypersalivation:\u003c\/strong\u003e Anorexia and excessive drooling are among the post-approval adverse events reported by dog owners and veterinary professionals after use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eStore at or Below 30°C:\u003c\/strong\u003e Keep this product at or below 30°C (86°F), though brief exposure to temperatures as high as 40°C (104°F) will not compromise its quality or effectiveness.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSecure Away from Pets:\u003c\/strong\u003e Tuck the tablets away somewhere completely out of any pet's reach to avoid the risk of accidental self-dosing or overdose.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eKeep Away from Children:\u003c\/strong\u003e As with all prescription pet medications, always store Simparica where children have no access to it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" target=\"_blank\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" target=\"_blank\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\n\u003ch3\u003eQ1: What is Simparica 120mg brown pack used for in extra-large dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Simparica 120 mg is a monthly prescription flea and tick chewable for extra-large dogs weighing 88.1 to 132 lbs. It kills adult fleas, prevents re-infestation, controls six tick species, and is FDA-approved to help block Lyme disease-causing infections in eligible dogs.\u003c\/p\u003e\n\n\u003ch3\u003eQ2: How fast does Simparica sarolaner chew work against deer ticks on large dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Simparica wipes out more than 98% of deer tick infestations in as little as 12 hours after a single dose. That matters because deer ticks generally need anywhere from 24 - 48 hours to pass on Lyme disease, making that rapid action especially valuable for large dogs that spend a lot of time outdoors.\u003c\/p\u003e\n\n\u003ch3\u003eQ3: Can Simparica extra-large dog chew be given during bath time or swimming?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Since Simparica is an oral medication that gets absorbed into the bloodstream, water simply plays no role in how well it works. Whether your dog loves swimming, needs regular baths, or spends time outdoors in the rain, the protection stays just as strong — making it a great fit for active and water-loving breeds.\u003c\/p\u003e\n\n\u003ch3\u003eQ4: What should I do if my extra-large dog misses a monthly Simparica dose?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e On a missed dose, go ahead and give the 120 mg tablet when you notice and pick up the regular monthly schedule from that point. Avoid giving two doses at once to make up for the missed one. When in doubt about the timing or your dog's current health, check in with your vet before starting back up.\u003c\/p\u003e\n\n\u003ch3\u003eQ5: Is Simparica flea and tick tablet safe for extra-large dogs with a seizure history?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Simparica belongs to the isoxazoline class, which has been linked to neurological signs including tremors, unsteadiness, and seizures in some dogs, even those without prior seizure history. Dogs with a known seizure or neurological disorder history should only receive this medication under direct veterinary guidance.\u003c\/p\u003e\n\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.avma.org\/resources-tools\/pet-owners\/petcare\/flea-and-tick-control-pets\" target=\"_blank\" rel=\"noopener\" title=\"American veterinary medical association (avma) – flea and tick control in pets\" aria-label=\"Visit a webpage about American veterinary medical association (avma) – flea and tick control in pets\"\u003eAmerican Veterinary Medical Association (AVMA) – Flea and Tick Control in Pets\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.fda.gov\/animal-veterinary\/animal-health-literacy\/safe-use-isoxazoline-flea-and-tick-products\" target=\"_blank\"\u003eFDA – Safe Use of Isoxazoline Flea and Tick Products\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/capcvet.org\/guidelines\/tick-borne-diseases\/\" target=\"_blank\"\u003eCompanion Animal Parasite Council (CAPC) – Tick-Borne Diseases in Dogs\u003c\/a\u003e\u003c\/p\u003e","brand":"Zoetis","offers":[{"title":"1 Chewable Tablet (1 month supply)","offer_id":41244937519265,"sku":"10012456-1","price":135.0,"currency_code":"RON","in_stock":true},{"title":"3 Chewable Tablets (3 month supply)","offer_id":41244937584801,"sku":"10012456","price":372.0,"currency_code":"RON","in_stock":true},{"title":"6 Chewable Tablets (6 month supply)","offer_id":41244937552033,"sku":"10012462","price":671.0,"currency_code":"RON","in_stock":true},{"title":"12 Chewable Tablets (12 month supply)","offer_id":44136249852065,"sku":"10012462-PK2","price":1342.0,"currency_code":"RON","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/simparica-for-large-dogs-88-1-132-lbs-3-chewable-tablets-3-month-619.jpg?v=1778103506","url":"https:\/\/hardypaw.com\/en-ro\/products\/simparica-flea-tick-chewables-large-dogs-brown-box","provider":"HardyPaw","version":"1.0","type":"link"}