{"product_id":"simplicef","title":"Simplicef (cefpodoxime proxetil) Tablets - Antibiotic for Dogs","description":"\u003ch2\u003e\u003cstrong\u003eOnce Daily Skin Infection Treatment for Dogs\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSIMPLICEF Chewable Tablets are a veterinarian-prescribed oral antibiotic for skin infections like wounds,abscesses in dogs caused by susceptible bacteria. Formulated with cefpodoxime proxetil, this FDA-approved medication delivers broad-spectrum bactericidal activity in an easy-to-administer chewable form. Give once a day with or without food to support effective treatment outcomes.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #ff0000;\"\u003e\u003cstrong\u003ePlease note that the product may arrive in a Hardy Paw Pharmacy vial; manufacturer packaging is shown for reference.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eConvenient Once Daily:\u003c\/strong\u003e Administered once every 24 hours to help support treatment compliance for your dog.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroad Spectrum:\u003c\/strong\u003e Targets a range of susceptible bacteria responsible for common canine skin infections.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBactericidal Action:\u003c\/strong\u003e Works by disrupting bacterial cell wall synthesis to help eliminate infection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChewable Form:\u003c\/strong\u003e Scored chewable tablets are easier to give to dogs than conventional tablets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary Proven:\u003c\/strong\u003e Backed by research and approved under FDA NADA # 141-232 for canine use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eVariants\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e100 mg Chewable Tablets\u003c\/p\u003e\n\u003cp\u003e200 mg Chewable Tablets\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eActive Ingredients\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eCefpodoxime proxetil (equivalent to cefpodoxime) 100 mg or 200 mg per tablet.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended Dosage Chart\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003e5 mg\/kg Total Daily Dosage\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 43.6349%; height: 217px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eWeight of Dog (lbs)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"158\" style=\"width: 32.7609%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003e100 mg Tablets\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"148\" style=\"width: 30.7809%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003e200 mg Tablets\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e22 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"158\" style=\"width: 32.7609%; height: 35.5966px;\"\u003e\n\u003cp\u003e0.5 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"148\" style=\"width: 30.7809%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e44 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"158\" style=\"width: 32.7609%; height: 35.5966px;\"\u003e\n\u003cp\u003e1 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"148\" style=\"width: 30.7809%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e66 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"158\" style=\"width: 32.7609%; height: 35.5966px;\"\u003e\n\u003cp\u003e1.5 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"148\" style=\"width: 30.7809%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e88 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"158\" style=\"width: 32.7609%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"148\" style=\"width: 30.7809%; height: 35.5966px;\"\u003e\n\u003cp\u003e1 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e132 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"158\" style=\"width: 32.7609%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"148\" style=\"width: 30.7809%; height: 35.5966px;\"\u003e\n\u003cp\u003e1 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e10 mg\/kg Total Daily Dosage\u003c\/strong\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 48.6217%; height: 263px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eWeight of Dog (lbs)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"159\" style=\"width: 33.1209%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003e100 mg Tablets\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"146\" style=\"width: 30.4209%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003e200 mg Tablets\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e11 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"159\" style=\"width: 33.1209%; height: 35.5966px;\"\u003e\n\u003cp\u003e0.5 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"146\" style=\"width: 30.4209%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e22 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"159\" style=\"width: 33.1209%; height: 35.5966px;\"\u003e\n\u003cp\u003e1 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"146\" style=\"width: 30.4209%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e44 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"159\" style=\"width: 33.1209%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"146\" style=\"width: 30.4209%; height: 35.5966px;\"\u003e\n\u003cp\u003e1 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e66 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"159\" style=\"width: 33.1209%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"146\" style=\"width: 30.4209%; height: 35.5966px;\"\u003e\n\u003cp\u003e2 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e88 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"159\" style=\"width: 33.1209%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"146\" style=\"width: 30.4209%; height: 35.5966px;\"\u003e\n\u003cp\u003e2 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"172\" style=\"width: 35.821%; height: 35.5966px;\"\u003e\n\u003cp\u003e132 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"159\" style=\"width: 33.1209%; height: 35.5966px;\"\u003e\n\u003cp\u003e—\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"146\" style=\"width: 30.4209%; height: 35.5966px;\"\u003e\n\u003cp\u003e3 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003cbr\u003eSource:\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Information\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Sensitivity:\u003c\/strong\u003e Do not use in dogs with known hypersensitivity to cephalosporins or penicillins.\u003cbr\u003e\u003cstrong\u003eBreeding Safety:\u003c\/strong\u003e Safety has not been demonstrated in breeding, pregnant, or lactating dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCoombs Test:\u003c\/strong\u003e May occasionally induce a positive direct Coombs test result.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHandler Precaution:\u003c\/strong\u003e Avoid direct skin or mucous membrane contact to reduce allergic reaction risk.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVomiting:\u003c\/strong\u003e Reported in clinical field studies among dogs receiving cefpodoxime therapy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Mild gastrointestinal upset observed in a small number of treated dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDecreased Appetite:\u003c\/strong\u003e Reduced food intake noted in isolated cases during clinical evaluation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIncreased Thirst:\u003c\/strong\u003e Increased water consumption observed in dogs receiving active control during studies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature:\u003c\/strong\u003e Store at controlled room temperature between 20 and 25 degrees Celsius.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExcursion Range:\u003c\/strong\u003e Permitted temperature excursions range between 15 and 40 degrees Celsius.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecure Container:\u003c\/strong\u003e Replace the cap securely after each opening to maintain product integrity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eShipping \u0026amp; Return\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eQ1: What is SIMPLICEF Chewable used for in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e SIMPLICEF Chewable Tablets are indicated for treating canine skin infections, including wounds and abscesses, caused by susceptible bacteria such as Staphylococcus pseudintermedius, Staphylococcus aureus, Streptococcus canis, Escherichia coli, Pasteurella multocida, and Proteus mirabilis. It is approved for oral use in dogs only.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ2: How often should SIMPLICEF be given to dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e SIMPLICEF is administered orally 5 to 10 mg per kilogram of body weight once daily. Treatment typically continues for 5 to 7 days or 2 to 3 days beyond clinical resolution, not exceeding 28 days.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ3: Can SIMPLICEF be given with food?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e SIMPLICEF Chewable Tablets may be administered with or without food. Co-administration with food has been shown to increase the oral bioavailability of cefpodoxime, the active metabolite, potentially enhancing systemic exposure without changing the recommended dosing schedule.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ4: What are the possible side effects of SIMPLICEF in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e In clinical field studies, reported adverse reactions included vomiting, diarrhea, decreased appetite, and increased water consumption. These effects were observed in a small number of dogs and were generally mild. Contact your veterinarian if unusual symptoms occur.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ5: Is SIMPLICEF safe for puppies or breeding dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Target animal safety studies demonstrated tolerance at labelled doses in adult dogs and puppies. However, safety has not been established for dogs used for breeding, pregnant dogs, or lactating bitches. Consult your veterinarian before use in these populations.\u003c\/p\u003e","brand":"Zoetis","offers":[{"title":"100-mg \/ 100 tablets","offer_id":41817278578849,"sku":"10002044","price":1205.0,"currency_code":"RON","in_stock":true},{"title":"100-mg \/ 1 tablet","offer_id":41817278611617,"sku":"10002044-1","price":13.0,"currency_code":"RON","in_stock":true},{"title":"200-mg \/ 100 tablets","offer_id":45024063717537,"sku":"10001314","price":2325.0,"currency_code":"RON","in_stock":true},{"title":"200-mg \/ 1 tablet","offer_id":45024063750305,"sku":"10001314-1","price":24.0,"currency_code":"RON","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/simplicef-cefpodoxime-proxetil-tablets-antibiotic-for-dogs-pet-379.png?v=1778507019","url":"https:\/\/hardypaw.com\/en-ro\/products\/simplicef","provider":"HardyPaw","version":"1.0","type":"link"}