{"product_id":"proin-er-chewable-tablets-for-dogs-145-mg","title":"Proin ER Chewable Tablets for Dogs, 145 mg","description":"\u003ch2\u003eControls Urinary Incontinence in Dogs Effectively\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003ePROIN ER Chewable Tablets for Dogs are veterinarian-prescribed extended-release tablets formulated to help control urinary incontinence caused by urethral sphincter hypotonus. The medication contains phenylpropanolamine hydrochloride, an alpha-adrenergic agent that increases urethral muscle tone to improve bladder control. Designed for convenient once-daily dosing, these tablets support long-term management of urinary leakage in dogs when administered with food.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cspan class=\"TextRun SCXW3397344 BCX0\" lang=\"EN-US\" data-contrast=\"none\"\u003e\u003cspan class=\"NormalTextRun SCXW3397344 BCX0\"\u003ePlease note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.\u003c\/span\u003e\u003c\/span\u003e\u003cspan data-ccp-props='{\"134233117\":false,\"134233118\":false,\"335557856\":16777215,\"335559738\":0,\"335559739\":240}' class=\"EOP SCXW3397344 BCX0\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003e*Signature Is Required Upon Delivery In The Following States: Arkansas, Illinois, Iowa, Louisiana, Oregon, West Virginia\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Bladder Control:\u003c\/strong\u003e Helps \u003ca href=\"\/products\/proin-chewable-tablets-for-dogs-50mg?variant=41253184733345\" title=\"Proin chewable tablets for dogs 50mg\" aria-label=\"Proin chewable tablets for dogs 50mg\"\u003econtrol urinary incontinence in dogs\u003c\/a\u003e caused by urethral sphincter hypotonus by increasing urethral muscle tone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce Daily Dosing:\u003c\/strong\u003e Extended release formulation allows convenient once daily administration for effective long-term management of urinary leakage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImproves Urethral Tone:\u003c\/strong\u003e Phenylpropanolamine stimulates adrenergic receptors to enhance smooth muscle tone in the urethra and bladder neck.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinarian Prescribed Treatment:\u003c\/strong\u003e FDA-approved veterinary medication indicated specifically for managing urinary incontinence associated with urethral sphincter hypotonus.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtended Release Formula:\u003c\/strong\u003e Controlled-release tablets help maintain therapeutic levels of phenylpropanolamine for sustained urinary control.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eVariants\u003c\/h3\u003e\n\u003cp\u003ePROIN ER Chewable Tablets are available in the following strengths:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePROIN ER Chewable Tablets 18 mg tablets\u003c\/li\u003e\n\u003cli\u003ePROIN ER Chewable Tablets 38 mg tablets\u003c\/li\u003e\n\u003cli\u003ePROIN ER Chewable Tablets 74 mg tablets\u003c\/li\u003e\n\u003cli\u003ePROIN ER Chewable Tablets 145 mg tablets\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eComposition Table\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"278\"\u003e\n\u003cp\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\"\u003e\n\u003cp\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"278\"\u003e\n\u003cp\u003ePhenylpropanolamine Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\"\u003e\n\u003cp\u003e18 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"278\"\u003e\n\u003cp\u003ePhenylpropanolamine Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\"\u003e\n\u003cp\u003e38 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"278\"\u003e\n\u003cp\u003ePhenylpropanolamine Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\"\u003e\n\u003cp\u003e74 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"278\"\u003e\n\u003cp\u003ePhenylpropanolamine Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\"\u003e\n\u003cp\u003e145 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended-Dosage Chart\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"201\"\u003e\n\u003cp\u003e\u003cstrong\u003eDog Body Weight (lbs)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"221\"\u003e\n\u003cp\u003e\u003cstrong\u003ePROIN ER Tablet Strength\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"201\"\u003e\n\u003cp\u003e10–20 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"221\"\u003e\n\u003cp\u003e18 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"201\"\u003e\n\u003cp\u003e21–40 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"221\"\u003e\n\u003cp\u003e38 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"201\"\u003e\n\u003cp\u003e41–80 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"221\"\u003e\n\u003cp\u003e74 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"201\"\u003e\n\u003cp\u003e81–125 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"221\"\u003e\n\u003cp\u003e145 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003e\u003cstrong\u003eDosage \u0026amp; Administration Instructions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce Daily Dose:\u003c\/strong\u003e Administer PROIN ER at a recommended dosage of 2 to 4 mg\/kg body weight once daily.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGive With Food:\u003c\/strong\u003e Administer tablets with food to support consistent absorption and improve dosing tolerance in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDo Not Crush:\u003c\/strong\u003e Tablets must not be split or crushed because the extended release formulation ensures proper drug delivery.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e This medication is restricted to use by or on the order of a licensed veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSmall Dogs Warning:\u003c\/strong\u003e Dogs weighing under 10 pounds should not receive this product due to dosing safety limitations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer: \u003c\/strong\u003eThis dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnderlying Conditions:\u003c\/strong\u003e Use cautiously in dogs with heart disease, hypertension, liver disease, kidney insufficiency, diabetes, or glaucoma.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e Use carefully with sympathomimetic drugs, tricyclic antidepressants, monoamine oxidase inhibitors, or halogenated anesthetics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIncontinence Causes:\u003c\/strong\u003e The medication may mask incontinence caused by urinary tract infections and is ineffective for neurologic causes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Safety:\u003c\/strong\u003e The safety of this medication has not been studied in breeding dogs or in dogs that are pregnant or nursing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWater Availability:\u003c\/strong\u003e Dogs may feel more thirsty while taking this medication, so they should always have access to clean, fresh water.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDigestive Problems: \u003c\/strong\u003eWhile using phenylpropanolamine tablets, some pets may experience vomiting, loose stools, reduced appetite, or excessive drooling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChanges in Blood Pressure: \u003c\/strong\u003eThe medication may cause higher blood pressure and a faster heartbeat during treatment, so regular checks by a veterinarian are important.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBehavioral Changes:\u003c\/strong\u003e Anxiety, agitation, vocalization, confusion, and restlessness have been reported in some treated dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurologic Effects:\u003c\/strong\u003e Tremors, seizures, ataxia, or nervous system disturbances may occur rarely in some dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrinary Effects:\u003c\/strong\u003e Proteinuria, urinary tract infections, urinary retention, or hematuria have been reported during treatment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Store the tablets within the recommended 20°C–25°C room temperature range to help preserve product quality.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTemperature Excursions:\u003c\/strong\u003e Short temperature variations between 15°C and 40°C are permitted during storage and handling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecure Storage:\u003c\/strong\u003e Keep the medication in a secure location away from pets and other animals to prevent accidental ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What is PROIN ER used for in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PROIN ER Chewable Tablets are used to control urinary incontinence in dogs caused by urethral sphincter hypotonus. The medication contains phenylpropanolamine hydrochloride, which helps increase urethral muscle tone and \u003ca href=\"\/collections\/dog-kidney-bladder-supplements\" title=\"Dog kidney \u0026amp; bladder supplements: best for urinary health | hardypaw\" aria-label=\"Dog kidney \u0026amp; bladder supplements: best for urinary health | hardypaw\"\u003eimproves bladder control\u003c\/a\u003e, reducing urine leakage when administered as directed by a veterinarian.\u003c\/p\u003e\n\u003ch3\u003eQ2: How often should PROIN ER be given to dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PROIN ER is formulated as an extended-release medication and is generally given once a day based on the dog’s body weight and the veterinarian’s recommended dosage. The tablet should be administered with food and should not be crushed, broken, or divided, as this may interfere with the intended slow release of the medication.\u003c\/p\u003e\n\u003ch3\u003eQ3: Can small dogs take PROIN ER tablets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Dogs weighing less than 10 pounds should not receive PROIN ER because tablet dosing may exceed the safe recommended dosage of phenylpropanolamine. Veterinarians determine appropriate treatment options and dosing adjustments based on a dog’s body weight and health condition.\u003c\/p\u003e\n\u003ch3\u003eQ4: Are there any side effects associated with PROIN ER for dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Some dogs may develop side effects such as vomiting, diarrhea, reduced appetite, weight loss, high blood pressure, or changes in behavior while taking PROIN ER. If a dog shows any unusual signs or noticeable changes in health during treatment, the pet owner should reach out to a veterinarian as soon as possible for proper advice and evaluation.\u003c\/p\u003e\n\u003ch3\u003eQ5: How should PROIN ER tablets be stored?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Keep PROIN ER tablets in normal indoor conditions, ideally within the 20°C–25°C temperature range. Short periods of exposure to temperatures as low as 15°C or as high as 40°C will not affect the product. The medicine should be placed in a protected storage area where children and animals cannot reach it to avoid accidental consumption.\u003c\/p\u003e","brand":"PRN Pharmacal","offers":[{"title":"30 Tablets","offer_id":44643118842017,"sku":"30034757","price":50.04,"currency_code":"USD","in_stock":true},{"title":"90 Tablets","offer_id":44643118874785,"sku":"30034744","price":142.56,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/proin-er-chewable-tablets-for-dogs-145-mg-pet-medicine-503.jpg?v=1777818276","url":"https:\/\/hardypaw.com\/products\/proin-er-chewable-tablets-for-dogs-145-mg","provider":"HardyPaw","version":"1.0","type":"link"}