{"product_id":"proin-er-chewable-tablets-for-dogs-38-mg","title":"Proin ER Chewable Tablets for Dogs, 38mg","description":"\u003ch2\u003eEffective Urinary Incontinence Control Tablets for Dogs\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003ePROIN ER 38 mg is a vet-prescribed extended-release tablet. It is designed to \u003ca href=\"\/products\/cranmate-cranberry-supplement-tablets-dogs-cats?variant=44947128156321\" title=\"Cranmate cranberry supplement tablets for dogs and cats\" aria-label=\"Cranmate cranberry supplement tablets for dogs and cats\"\u003ehelp control urinary incontinence in dogs\u003c\/a\u003e caused by weak urethral sphincters. The tablet contains phenylpropanolamine hydrochloride. This substance increases urethral muscle tone and improves bladder control. With its convenient once-daily dosing and controlled drug release, PROIN helps reduce urine leakage. It supports better urinary management in dogs under veterinary care.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eSignature Is Required Upon Delivery In The Following States: Arkansas, Illinois, Iowa, Louisiana, Oregon, and West Virginia\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrinary Control Support: \u003c\/strong\u003eHelps manage urinary incontinence in dogs by strengthening urethral sphincter tone and reducing involuntary urine leakage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce-Daily Dosing: \u003c\/strong\u003eThe extended-release formulation allows for easy once-a-day administration, making long-term treatment simpler.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargeted Mechanism: \u003c\/strong\u003ePhenylpropanolamine stimulates adrenergic receptors, which increase urethral closure pressure and improve bladder control in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary-Approved Treatment:\u003c\/strong\u003e FDA-approved prescription medication specifically indicated for urinary incontinence caused by urethral sphincter weakness in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeight-Based Strengths:\u003c\/strong\u003e Available in multiple dosage strengths to support accurate dosing for dogs across different body weight ranges.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eVariants\u003c\/h3\u003e\n\u003cp\u003e18 mg tablets\u003cbr\u003e38 mg tablets\u003cbr\u003e74 mg tablets\u003cbr\u003e145 mg tablets\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003ePhenylpropanolamine Hydrochloride 38 mg\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eRecommended-Dosage Chart\u003c\/h4\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"160\"\u003e\n\u003cp\u003e\u003cstrong\u003eDog Body Weight\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"251\"\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Tablet Strength\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"160\"\u003e\n\u003cp\u003e10 to 20 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"251\"\u003e\n\u003cp\u003e18 mg tablet once daily\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"160\"\u003e\n\u003cp\u003e21 to 40 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"251\"\u003e\n\u003cp\u003e38 mg tablet once daily\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"160\"\u003e\n\u003cp\u003e41 to 80 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"251\"\u003e\n\u003cp\u003e74 mg tablet once daily\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"160\"\u003e\n\u003cp\u003e81 to 125 lbs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"251\"\u003e\n\u003cp\u003e145 mg tablet once daily\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGive With Food:\u003c\/strong\u003e Administer PROIN ER tablets with food to help support proper absorption and consistent drug activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDo Not Split:\u003c\/strong\u003e Extended-release tablets must not be split, crushed, or altered because this may affect controlled drug release.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeight-Based Dosing:\u003c\/strong\u003e Dose dogs according to body weight using the labeled tablet strengths to maintain recommended therapeutic dosing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary Prescription:\u003c\/strong\u003e This medication is restricted for veterinary use and should only be administered under the direction of a licensed veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonitor Consumption:\u003c\/strong\u003e Ensure the dog consumes the entire tablet after dosing and contact a veterinarian if dosing difficulties occur.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnderlying Conditions:\u003c\/strong\u003e Use cautiously in dogs with heart disease, hypertension, kidney disease, diabetes, glaucoma, or liver disorders.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e Use cautiously with sympathomimetic drugs, tricyclic antidepressants, monoamine oxidase inhibitors, or certain anesthetics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiagnostic Awareness:\u003c\/strong\u003e This medication may mask urinary incontinence symptoms caused by urinary tract infections or other underlying conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Safety:\u003c\/strong\u003e Safety has not been established for dogs intended for breeding or those that are pregnant or lactating.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDigestive upset: \u003c\/strong\u003eSome dogs may vomit, have diarrhea, or show a reduced appetite during treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlood pressure changes: \u003c\/strong\u003eSome dogs may have increased blood pressure or heart rate changes, such as tachycardia.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBehavior changes: \u003c\/strong\u003eDogs might experience restlessness, agitation, or lethargy while receiving phenylpropanolamine treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeight changes: \u003c\/strong\u003eA significant body weight reduction during long treatment periods has been noticed in dogs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature:\u003c\/strong\u003e Store tablets at controlled room temperature ranging between 20°C and 25°C for optimal stability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTemperature Excursions:\u003c\/strong\u003e Short temperature variations between 15°C and 40°C are permitted during storage and transportation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecure Storage:\u003c\/strong\u003e Keep medication stored securely away from the reach of pets and children to prevent accidental exposure and ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eShipping \u0026amp; Return\u003c\/h4\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy\" aria-label=\"Shipping policy\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What is PROIN ER 38 mg used for in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PROIN ER 38 mg is a prescription medication used to control urinary incontinence in dogs caused by urethral sphincter hypotonus. It works by increasing urethral muscle tone, helping \u003ca href=\"\/collections\/dog-kidney-urinary-medications\" title=\"Dog kidney \u0026amp; urinary tract medications: prevent stones \u0026amp; infections | hardypaw\" aria-label=\"Dog kidney \u0026amp; urinary tract medications: prevent stones \u0026amp; infections | hardypaw\"\u003ereduce urine leakage\u003c\/a\u003e, improve bladder control, and, in affected dogs,s when administered under veterinary supervision.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does PROIN ER help manage urinary incontinence in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PROIN ER contains phenylpropanolamine hydrochloride, an alpha-adrenergic agent that increases urethral sphincter tone. By stimulating adrenergic receptors and promoting norepinephrine release, it improves urethral closure pressure, helping dogs maintain better urinary control and reducing accidental urine leakage.\u003c\/p\u003e\n\u003ch3\u003eQ3: How should PROIN ER tablets be given to dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PROIN ER tablets should be given once a day with food, based on the dosage recommended by a veterinarian. The tablets must not be split or crushed, as they are extended-release. Owners should make sure the dog takes the full dose during administration.\u003c\/p\u003e\n\u003ch3\u003eQ4: Are there any common side effects of PROIN ER in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Some dogs may experience side effects such as vomiting, diarrhea, decreased appetite, weight loss, lethargy, or increased blood pressure during treatment. These reactions were reported during clinical studies and should be discussed with a veterinarian if they occur or worsen.\u003c\/p\u003e\n\u003ch3\u003eQ5: Can all dogs take PROIN ER for urinary incontinence?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns: \u003c\/strong\u003ePROIN ER is not suitable for every dog and should only be used with veterinary guidance. It may not work for incontinence caused by neurologic disease or anatomical issues. Use it carefully in dogs with heart disease, high blood pressure, or specific medical conditions.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"PRN Pharmacal","offers":[{"title":"30 Tablets","offer_id":44643119759521,"sku":"30034557","price":30.27,"currency_code":"USD","in_stock":true},{"title":"90 Tablets","offer_id":44643119792289,"sku":"30034544","price":86.31,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/proin-er-chewable-tablets-for-dogs-38mg-pet-medicine-597.jpg?v=1778103813","url":"https:\/\/hardypaw.com\/products\/proin-er-chewable-tablets-for-dogs-38-mg","provider":"HardyPaw","version":"1.0","type":"link"}