{"product_id":"vetoquinol-simplera-otic-solution-dogs","title":"Simplera Otic Solution for Dogs, 1-mL","description":"\u003cp align=\"center\"\u003e\u003cimg src=\"https:\/\/hardypaw.com\/cdn\/shop\/files\/rx-map.webp\" class=\"img-responsive\" alt=\"RX MAP\" width=\"700\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch2\u003eSingle-Dose Ear Infection Treatment for Dogs\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eSIMPLERA Otic Solution is a veterinarian-administered, single-dose \u003ca href=\"\/products\/baytril-otic-15-ml?variant=41824605339809\" title=\"Baytril otic for dogs | prescription ear medication | hardypaw\" aria-label=\"Baytril otic for dogs | prescription ear medication | hardypaw\"\u003eear treatment for dogs\u003c\/a\u003e with otitis externa caused by susceptible bacteria and yeast. Its triple-action formula combines antibacterial, antifungal, and anti-inflammatory agents to help relieve infection and inflammation for up to 30 days. The convenient single-use dropperette supports treatment compliance while reducing the need for repeated at-home ear medication by pet owners.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple-Action Formula\u003c\/strong\u003e: Combines florfenicol, terbinafine, and mometasone to target bacteria, yeast, and inflammation associated with canine otitis externa.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConvenient Single Dose\u003c\/strong\u003e: Single-use dropperette eliminates daily ear medication routines, improving compliance for dogs and their owners during treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLong-Lasting Relief\u003c\/strong\u003e: A single administered dose is designed to provide therapeutic effect for approximately 30 days after treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVet-Controlled Treatment\u003c\/strong\u003e: Administration by veterinary professionals helps ensure proper dosing, ear evaluation, and appropriate patient selection before use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Proven Results\u003c\/strong\u003e: Field study demonstrated 72.5% treatment success compared with 11.1% in the vehicle control group.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eVariants\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e1 mL single-dose dropperette\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eComposition Table\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 41.6758%; height: 93px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 27.0008%; height: 35.5966px;\" width=\"152\"\u003e\n\u003cp\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 72.7221%; height: 35.5966px;\" width=\"446\"\u003e\n\u003cp\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 27.0008%; height: 35.5966px;\" width=\"152\"\u003e\n\u003cp\u003eFlorfenicol\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 72.7221%; height: 35.5966px;\" width=\"446\"\u003e\n\u003cp\u003e16.6 mg\/mL\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 55.1989px;\"\u003e\n\u003ctd style=\"width: 27.0008%; height: 55.1989px;\" width=\"152\"\u003e\n\u003cp\u003eTerbinafine\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 72.7221%; height: 55.1989px;\" width=\"446\"\u003e\n\u003cp\u003e14.8 mg\/mL (equivalent to 16.6 mg\/mL terbinafine hydrochloride)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 27.0008%; height: 35.5966px;\" width=\"152\"\u003e\n\u003cp\u003eMometasone furoate\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 72.7221%; height: 35.5966px;\" width=\"446\"\u003e\n\u003cp\u003e2.2 mg\/mL\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003e\u003cstrong\u003eOther Ingredients\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003ePurified water, propylene carbonate, propylene glycol, ethyl alcohol, polyethylene glycol.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended-Usage Chart\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 40.7853%; height: 72px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 55.1989px;\"\u003e\n\u003ctd style=\"width: 10.2603%; height: 55.1989px;\" width=\"57\"\u003e\n\u003cp\u003e\u003cstrong\u003eSpecies\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 21.9606%; height: 55.1989px;\" width=\"122\"\u003e\n\u003cp\u003e\u003cstrong\u003eCondition Treated\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 19.8006%; height: 55.1989px;\" width=\"110\"\u003e\n\u003cp\u003e\u003cstrong\u003eDose\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 19.8006%; height: 55.1989px;\" width=\"110\"\u003e\n\u003cp\u003e\u003cstrong\u003eFrequency\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 27.1808%; height: 55.1989px;\" width=\"151\"\u003e\n\u003cp\u003e\u003cstrong\u003eAdministration\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 94.4034px;\"\u003e\n\u003ctd style=\"width: 10.2603%; height: 94.4034px;\" width=\"57\"\u003e\n\u003cp\u003eDogs\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 21.9606%; height: 94.4034px;\" width=\"122\"\u003e\n\u003cp\u003eOtitis externa is associated with susceptible bacteria and yeast\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 19.8006%; height: 94.4034px;\" width=\"110\"\u003e\n\u003cp\u003e1 mL (one dropperette) per affected ear\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 19.8006%; height: 94.4034px;\" width=\"110\"\u003e\n\u003cp\u003eSingle administration\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 27.1808%; height: 94.4034px;\" width=\"151\"\u003e\n\u003cp\u003eAdministered into the external ear canal by veterinary personnel\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003e\u003cstrong\u003eProduct Preparation\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrepare Dropperette\u003c\/strong\u003e: Remove the cap, reverse it onto the tip, twist to break the seal, then attach the applicator nozzle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShake Before Use\u003c\/strong\u003e: Shake the dropperette well before administration to ensure proper mixing of the suspension components.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cimg alt=\"Simplera Otic Solution for Dogs 1-mL\" src=\"https:\/\/hardypaw.com\/cdn\/shop\/files\/simplera-instructions.jpg\" data-original=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/simplera-instructions.jpg?v=1722005734\" data-files=\"simplera-instructions.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eDosage \u0026amp; Administration Instructions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEar Preparation: \u003c\/strong\u003eClean and dry the \u003ca href=\"\/products\/zymox-veterinary-strength-ear-cleanser-dogs-cats\" title=\"Zymox veterinary strength ear cleanser liquid for dogs \u0026amp; cats\" aria-label=\"Zymox veterinary strength ear cleanser liquid for dogs \u0026amp; cats\"\u003eexternal ear canal\u003c\/a\u003e thoroughly before administering the solution to improve treatment effectiveness.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMembrane Verification: \u003c\/strong\u003eConfirm the tympanic membrane (eardrum) is intact before administration to reduce the risk of complications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSingle Dose Use: \u003c\/strong\u003eInsert the dropperette tip into the ear canal and instill the entire 1 mL contents.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMassage Ear Base: \u003c\/strong\u003eGently massage the base of the ear after administration to help distribute the solution.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevent Head Shaking: \u003c\/strong\u003eHold the dog after application to minimize shaking and reduce the risk of splatter exposure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary Prescription: \u003c\/strong\u003eThis medication is restricted for use by a licensed veterinarian or on their order only.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Information\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDogs Only\u003c\/strong\u003e: Product is intended for dogs only and should not be used in cats due to reported adverse reactions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMembrane Integrity: \u003c\/strong\u003eDo not use in dogs with known tympanic membrane perforation because of the risk of complications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver Caution:\u003c\/strong\u003e Use carefully in dogs with poor liver function, as systemic effects may happen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEye Protection: \u003c\/strong\u003eUse eye protection during administration and try to minimize dog head shaking to avoid accidental eye exposure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Safety\u003c\/strong\u003e: The safety has not been evaluated in breeding dogs, pregnant dogs, or lactating females.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEar Discomfort\u003c\/strong\u003e: Reported reactions include ear discharge, pain, irritation, and persistent head shaking after administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBalance Issues\u003c\/strong\u003e: Vestibular signs such as ataxia, head tilt, or nystagmus have been reported in treated dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHearing Changes\u003c\/strong\u003e: Deafness or internal ear disorders have been reported during post-approval adverse event monitoring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEye Reactions\u003c\/strong\u003e: Corneal ulcers and eye irritation may occur from splatter exposure if the dog shakes its head.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDigestive Signs\u003c\/strong\u003e: Vomiting has been reported in some dogs following treatment during adverse event monitoring.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature\u003c\/strong\u003e: Store between 20°C and 25°C with permitted excursions between 15°C and 30°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOriginal Packaging\u003c\/strong\u003e: To maintain integrity, keep the product in its original blister packaging until use\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChild Safety\u003c\/strong\u003e: Keep this medication stored away from children to prevent accidental exposure or ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eShipping \u0026amp; Return \u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eQ1: What conditions does SIMPLERA treat in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e SIMPLERA is used to treat otitis externa in dogs caused by certain yeasts, like Malassezia pachydermatis, and bacteria, including Staphylococcus pseudintermedius. It \u003ca href=\"\/products\/mometamax-single-otic-suspension-for-dogs-0-8ml-20-count\" title=\"Mometamax single-dose otic suspension for dogs | hardypaw\" aria-label=\"Mometamax single-dose otic suspension for dogs | hardypaw\"\u003econtains antibacterial, antifungal, and anti-inflammatory agents\u003c\/a\u003e to tackle infection and inflammation at the same time in affected ears.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ2: How long does one dose of SIMPLERA last?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e A single administered dose of SIMPLERA is designed to provide therapeutic effectiveness for approximately 30 days. Cleaning the ear after treatment may reduce product effectiveness, so veterinarians typically recommend avoiding additional ear cleaning unless specifically instructed during the treatment period.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ3: Can pet owners administer SIMPLERA at home?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e SIMPLERA should be administered by veterinary personnel only because federal law restricts its use to licensed veterinarians or their order. Proper ear examination and confirming an intact tympanic membrane are required before administration to ensure safe and appropriate treatment.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ4: Is SIMPLERA safe for cats or other pets?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e SIMPLERA is intended for use in dogs only and should not be used in cats. Adverse events have been reported following extra-label use in cats, including neurological and ear-related complications, which is why the product labeling specifically contraindicates feline use.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ5: What should I monitor after my dog receives SIMPLERA?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Dog owners should watch for signs like ear pain, irritation, vomiting, head shaking, head tilt, incoordination, or eye discharge after treatment. If any unusual symptoms appear, it’s a good idea to contact a veterinarian right away to assess the dog and decide on the right care.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003cp\u003eFor more detailed information, refer to the \u003ca href=\"https:\/\/www.fda.gov\/animal-veterinary\/cvm-updates\/fda-approves-simplera-otic-solution-treat-ear-infections-dogs\" title=\"Fda approves simplera otic solution to treat ear infections in dogs | fda\" aria-label=\"Visit a webpage about Fda approves simplera otic solution to treat ear infections in dogs | fda\"\u003eFDA Approval Announcement for Simplera Otic Solution\u003c\/a\u003e\u003c\/p\u003e","brand":"Vetoquinol","offers":[{"title":"Default Title","offer_id":44522014245025,"sku":"457394","price":28.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/simplera-otic-solution-for-dogs-1-ml-pet-medication-108.jpg?v=1778150167","url":"https:\/\/hardypaw.com\/products\/vetoquinol-simplera-otic-solution-dogs","provider":"HardyPaw","version":"1.0","type":"link"}