Sporimune (Cyclosporine) USP Modified, 25mg (15 capsules)

Helps Manage Atopic Dermatitis Symptoms in Dogs

Product Description

Sporimune (Cyclosporine) USP Modified 25 mg is an oral medication that helps control atopic dermatitis in dogs weighing at least 4 lbs. It targets immune responses linked to allergic skin problems, which helps reduce itching and inflammation. The modified microemulsion formulation ensures consistent absorption, making it suitable for long-term management of chronic skin conditions under veterinary care. Manufactured for Dechra Veterinary Products.

Benefits

• Immune Modulation: Helps suppress T cell activation and interleukin-2 production involved in allergic skin inflammation in dogs.
• Reduces Itching: Demonstrated improvement in pruritus scores in clinical studies of dogs with atopic dermatitis.
• Non Steroidal: Provides an alternative to corticosteroids or antihistamines for managing chronic allergic skin disease.
• Flexible Dosing: Daily dosing can be tapered to less frequent administration once clinical improvement is achieved.
• Consistent Absorption: Modified microemulsion formulation enhances bioavailability in aqueous environments after oral administration.

Ingredients

Cyclosporine 25 mg per capsule

How to Use

Recommended Dosage Chart

Dosage & Administration Instructions

• Veterinary Prescription: This medication is for use only by a licensed veterinarian or as instructed by one.
• Initial Dosing: The recommended starting dose is 5 mg per kg of body weight once a day for the first 30 days.
• Maintenance Adjustment: After improvement, the dosage may be changed to every other day or twice a week as directed.
• Meal Timing: Administer at least one hour before feeding or two hours after meals for optimal absorption.
• Missed Dose: In case a dose is missed, give the next dose as soon as possible without doubling the frequency.
• Capsule Handling: Capsules should not be opened or broken, and hands should be washed after administration.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Age Restrictions: Safety has not been established in dogs younger than six months or weighing less than four pounds.
• Breeding Warning: Not suitable for breeding dogs, pregnant animals, or nursing females as there is not enough safety data.
• Diabetes Risk: Use it with caution in dogs with diabetes mellitus, as cyclosporine may raise blood glucose levels.
• Drug Interactions: Medications that affect the cytochrome P450 enzyme system can significantly change cyclosporine blood levels.
• Infection Susceptibility: The immunosuppressive effects may make dogs more prone to infections or worsen existing hidden conditions.
• Renal Caution: Use it carefully in dogs with kidney problems since safety in those with renal insufficiency is not known.

Possible Side Effects

• Gastrointestinal Signs: Vomiting and diarrhea were the most commonly reported adverse reactions during clinical field studies.
• Lethargy Effects: Some dogs experienced lethargy, decreased appetite, or behavioral changes while receiving cyclosporine treatment.
• Gum Changes: Gingival hyperplasia or swollen gums may occur, but often regress after dosage reduction.
• Infection Risk: Persistent ear infections or urinary tract infections have been observed during treatment in some dogs.
• Neurologic Signs: Rare neurologic effects such as tremors or seizures have been reported during cyclosporine administration.
• Metabolic Changes: Elevated blood glucose or development of diabetes mellitus has been reported in some treated dogs.

Storage Information

• Room Temperature Storage: Store Sporimune capsules at 68°F-77°F or 20°C to 25°C to maintain stability and effectiveness. 
• Original Packaging: Keep the capsules in their original unit-dose blister packaging to protect the medication from environmental exposure.
• Secure Placement: Store the medication in a secure place away from children and pets to avoid accidental exposure.

Shipping & Return 

We offer ground, express, priority, and international delivery; see our shipping policy for details. 

For return instructions or product concerns, please refer to our detailed refund policy.  

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Sporimune used for in dogs?

Ans: Sporimune (cyclosporine capsules) is used to control atopic dermatitis in dogs that weigh at least 4 lbs. It helps by adjusting the immune system to lower inflammation and itching tied to allergic skin disease. It is not a steroid or antihistamine.

Q2: How long does Sporimune take to work in dogs?

Ans: Clinical studies showed that itching and skin lesion severity improved within the first 30 days of treatment at the recommended dose. Some dogs may need continued therapy and changes in dosage to reach the best long-term control of symptoms, as directed by a veterinarian.

Q3: How should Sporimune be given to dogs?

Ans: Sporimune should be given at least one hour before meals or two hours after meals to support proper absorption. Do not open or break the capsules. Always follow your veterinarian’s dosing instructions and do not give doses more often than recommended.

Q4: Can Sporimune dosage be reduced over time?

Ans: Yes, after the initial daily treatment period, the dosing frequency may be gradually reduced to every other day or twice a week once clinical improvement is seen. The goal is to keep the desired therapeutic effect while using the lowest effective dosing frequency decided by a veterinarian.

Q5: What are the common side effects of Sporimune in dogs?

Ans: The most commonly reported side effects are vomiting and diarrhea. Other possible reactions include lethargy, gingival hyperplasia, infections like otitis externa, and decreased appetite. Many mild gastrointestinal signs may go away with ongoing treatment or short-term dose changes under veterinary supervision.