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Megestrol Acetate 20mg Tablets (Manufacturer may vary)

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HardyPaw SKU: 481301-1

Size: 1 tablet

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Megestrol Acetate 20mg Tablets for Pets

Hormonal Therapy for Estrus Suppression and Appetite Stimulation

Megestrol acetate is a synthetic progestin used in veterinary medicine to manage hormone-related conditions in female dogs and cats. At 20mg strength, these tablets offer an effective non-surgical solution for estrus suppression, false pregnancy (pseudopregnancy), behavioral management, and occasionally appetite stimulation in companion animals. This product is veterinarian-prescribed and primarily used for canine and feline reproductive health, aligning with treatment protocols for animals not suitable for spaying or requiring temporary hormonal regulation.

Unlike many over-the-counter hormonal therapies, HardyPaw’s Megestrol 20mg Tablets deliver precise dosing, superior formulation consistency, and trusted safety—making it a preferred choice among pet owners and veterinarians alike.

All prescription items are Non-Refundable and Non-Returnable.

What Are the Benefits of Megestrol Acetate 20mg Tablets for Dogs and Cats?

Megestrol tablets are especially useful when spaying is not an option due to age, health issues, or breeding plans. The key therapeutic uses and benefits include:

  • Estrus Suppression (Heat Prevention): Temporarily halts the estrous cycle in intact female dogs and cats, reducing mating behavior and bleeding.

  • Treatment of False Pregnancy (Pseudopregnancy): Alleviates symptoms like nesting, milk production, and behavioral changes caused by hormonal imbalance.

  • Behavioral Modification: Helps manage hormone-driven aggression, restlessness, and mounting behaviors.

  • Appetite Stimulation in Cats (Off-label Use): May aid in increasing appetite in cats suffering from chronic illnesses like cancer or renal disease.

  • Non-Surgical Reproductive Control: Offers an alternative to spaying in cases where surgery is not feasible or desirable.

Dosage and Administration of Megestrol Acetate 20mg Tablets

Always consult your veterinarian for exact dosage instructions depending on your pet's condition. The dosage may vary based on weight, species, and treatment purpose.

Typical Guidelines (For Reference Only):

Animal Indication Suggested Dose Duration
Dog Estrus suppression 0.5 mg/lb/day 8 days
Dog False pregnancy 0.5 mg/lb/day 8 days
Cat Estrus suppression 2.5–5 mg/day 3–5 days

⚠️ Do not administer without veterinary direction. Overuse or incorrect dosing can lead to serious side effects.

Tips from Fellow Pet Owners for Giving Megestrol

Here’s how other pet owners are administering Megestrol successfully:

  • Wrap in a soft treat – Pill pockets or cheese work great!

  • Crush and mix with wet food – Especially effective with cats

  • Same time daily – Consistency helps avoid missed doses and side effects

  •  Don’t double dose if you miss one – Just continue with the next scheduled dose

💡 Pro Tip: Log your pet’s cycle or symptoms in a journal. This helps your vet monitor treatment success and avoid unnecessary use.

What Ingredients Are in Megestrol Tablets?

Each tablet contains:

  • Megestrol Acetate – 20 mg (active synthetic progestin)

  • Inactive ingredients: May vary by manufacturer (excipients used in tablet formulation)

What Are the Possible Side Effects of Megestrol for Pets?

While generally safe when used as prescribed, Megestrol acetate may cause:

  • Weight gain

  • Lethargy

  • Mammary gland enlargement

  • Diabetes mellitus (in long-term use)

  • Behavioral changes

  • Reversible fertility suppression

Long-term or off-label use increases risk. Routine monitoring of blood sugar and hormonal levels is recommended for prolonged therapy.

What Warnings and Precautions Should I Know Before Giving Megestrol?

  • Not for use in pregnant or lactating animals

  • Do not use in pets with diabetes, uterine infections, or cancer

  • Use caution in older pets or those with liver/kidney disorders

  • Keep out of reach of children and other animals

  • For veterinary use only

Storage Information

  • Store in a cool, dry place at room temperature (20°C – 25°C)

  • Protect from moisture and direct sunlight

  • Keep in original packaging until use

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Megestrol Acetate 20mg Tablets FAQs

What is Megestrol used for in dogs and cats?

Megestrol is used for estrus suppression, managing false pregnancy, behavioral regulation, and sometimes as an appetite stimulant, especially in felines.

Can Megestrol be used long-term in pets?

Long-term use increases the risk of side effects such as diabetes and reproductive system changes. It's best suited for short-term or temporary hormonal control under vet supervision.

Is Megestrol safe for diabetic pets?

No, it is contraindicated in diabetic animals as it can raise blood sugar levels and exacerbate the condition.

How quickly does Megestrol work in dogs?

For estrus suppression, results are typically seen within 3–5 days, depending on the timing of administration relative to the heat cycle.

Can I use Megestrol to delay heat cycles in breeding dogs?

Yes, when prescribed by a vet, it can delay heat cycles. However, it should not replace long-term reproductive planning or responsible breeding practices.

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