Sertraline HCI Tablets, 100mg

Behavioral Support Tablets for Anxiety and Compulsive Disorders in Pets

Product Description

Sertraline HCl 100mg Tablets are a prescription selective serotonin reuptake inhibitor used by veterinarians to manage anxiety-driven and compulsive behavioral disorders in dogs and cats. It works by keeping serotonin active in the brain for longer, which gradually builds emotional stability and softens fear-based responses over time. Veterinarians prescribe it for aggression, noise phobias, obsessive-compulsive behaviors, separation anxiety, and urine spraying in cats, and it works best when paired with a structured behavioral modification plan.

Benefits

• Separation Anxiety Relief: Dogs dealing with separation distress tend to respond better when this medication is part of a broader behavior and management plan.
• Obsessive-Compulsive Disorder: Repetitive behaviors like excessive licking, tail chasing, and pacing become more manageable in dogs and cats with consistent use.
• Cat Urine Spraying: Reduces stress-driven urine marking and house-soiling in cats dealing with anxiety or territorial behavioral issues.
• Noise Phobia and Fear: Takes the edge off exaggerated fear responses to loud noises, strangers, and other anxiety-triggering situations in pets.
• Aggression Reduction: Part of a broader behavioral treatment plan to help ease anxiety-driven or fear-based aggression in dogs and cats.

Ingredients

Active Ingredients

Sertraline Hydrochloride

How to Use

Sertraline HCl 100mg Tablets are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.

Please follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.

Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.

Placing this tablet inside a soft pill pocket or pill wrap treat is a simple way to get your pet to take their dose without any fuss. Pairing it with a small meal is also a sensible move, since it can help keep stomach discomfort from coming up during treatment.

Shop Pill Pockets for Dogs | Shop Pill Pockets for Cats

Additional Information

Precautions

• Avoid With MAOIs: Pets that have received a monoamine oxidase inhibitor like selegiline or amitraz in the past 14 days should not be given this medication.
• No Amitraz Flea Collars: Flea or tick collars containing amitraz should not be used while a pet is on sertraline due to the serious MAOI interaction risk.
• Never Stop Abruptly: Cutting this medication off without tapering can bring on withdrawal signs, so always bring the dose down gradually with veterinary guidance.
• Caution in Liver Disease: Pets with liver disease may need a reduced dose given less often, since the liver is responsible for processing sertraline.
• Caution in Seizure History: Pets that have had seizures in the past should be assessed carefully, as this medication can bring the seizure threshold down.
• Avoid in Pregnancy: Sertraline's safety in breeding, pregnant, or nursing animals is not well understood, so a veterinarian should be consulted before starting.
• Serotonin Syndrome Risk: Pairing this medication with serotonergic drugs like trazodone, tramadol, or amitriptyline can trigger life-threatening serotonin syndrome in pets.

Possible Side Effects

• Poor Appetite and Lethargy: A drop in appetite and lower energy are among the more commonly noticed reactions in dogs and cats starting sertraline.
• Digestive Upset: Vomiting, diarrhea, and drooling can come up early in treatment and tend to be mild and short-lived in most pets.
• Tremors and Restlessness: Mild tremors or agitation may show up in the first weeks as the pet's system gets used to the medication.
• Paradoxical Aggression: In rare cases, sertraline can make aggression worse in dogs, which means stopping the medication and checking in with a veterinarian right away.
• Serotonin Syndrome Signs: Tremors, seizures, a high body temperature, a racing heart, and vomiting all point to a serious emergency that needs immediate veterinary care.

Storage Information

• Room Temperature: Tablets do best at room temperature inside a tightly closed container, away from heat and moisture.
• Protect From Light: A dark, dry spot away from direct sunlight helps keep the medication stable and effective over its shelf life.
• Secure From All Animals: This medication should be stored somewhere completely out of reach of all pets and children, since accidental ingestion can be dangerous.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: Is sertraline FDA-approved for use in dogs and cats?

Ans: Sertraline does not hold FDA approval for veterinary use but is a legal off-label prescription that veterinarians can write for dogs and cats. The medication is FDA-approved for human use, and prescribing it for animals in appropriate situations falls within the legal scope of veterinary practice.

Q2: Does sertraline work immediately for behavioral problems in pets?

Ans: Sertraline does not kick in right away. Most pets need several weeks of consistent dosing before real behavioral improvement starts to show, and full effects can take up to six to eight weeks. A drop in appetite or some low energy early on is normal and tends to settle as the pet adjusts.

Q3: Does sertraline work better alongside behavioral training for pets?

Ans: Sertraline works best when it is part of a broader plan that includes training, environmental changes, and management strategies rather than being used on its own. On its own, medication rarely gets to the root of complex behavioral issues. A veterinarian or certified animal behaviorist can help put together a plan that covers both sides effectively.

Q4: What should I watch for when my pet first starts sertraline 100mg?

Ans: Keep a close eye on your pet in the first few weeks for reduced appetite, tiredness, tremors, digestive issues, or any shift in behavior. Dogs showing increased aggression need to come off the medication right away. Let your veterinarian know if anything worrying comes up or if there is no sign of improvement after several weeks.

Q5: How is sertraline discontinued safely in dogs and cats?

Ans: Bringing sertraline to a sudden stop is not safe and can cause withdrawal effects like agitation, nausea, and behavioral setbacks. A veterinarian will put together a step-down plan that gradually reduces the dose over several weeks. Following the tapering schedule closely is important for getting off the medication safely.