NexGard COMBO Topical for Cats 1.8-5.5 lbs (Purple Box)

Nexgard COMBO ((esafoxolaner, eprinomectin, and praziquantel topical solution) is a topical solution meant for use in cats. All cats, indoor and outdoor, need parasite protection and NexGard COMBO topical solution is specifically formulated to give cats the protection they need. 

Cats may play it cool, but they’re always at risk of parasites, whether they’re indoor or outdoor pets. Other pets in the home can bring parasites indoors, rodents that cats find can carry roundworms or hookworms, and ticks can even hitch a ride inside on your clothing after a day of hiking. That’s why it’s important that your cat receives regular, One-And-Done monthly protection.

It is safe and approved for cats and kittens as young as 8 weeks old, weighing 1.8 pounds or more. 

Benefits

• Kills adult fleas before they can lay eggs
• Kills black-legged ticks and lone star ticks
• Effectively prevents heartworm disease
• Treats and controls hookworms, roundworms, and tapeworms
• First and only feline broad spectrum parasite protection that kills tapeworms.
• Year-round protection from harmful parasites when applied monthly
• Convenient one-and-done dosing that lasts for a full month

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.

Dosage and Administration:

NexGard COMBO is dosed at a minimum of 0.055 mL/lb (0.12 mL/kg), which delivers a minimum dose of 0.65 mg/lb (1.44 mg/kg) esafoxolaner, 0.22 mg/lb (0.48 mg/kg) eprinomectin, and 4.53 mg/lb (9.98 mg/kg) praziquantel.

For heartworm disease prevention, apply once monthly for at least three months after last exposure to mosquitoes.

Administer the entire contents of a NexGard COMBO unit applicator topically once a month as specified in the following table:

Dosing Schedule:

A veterinarian or veterinary technician should demonstrate or instruct the pet owner regarding the appropriate technique for applying NexGard COMBO topically to cats and kittens prior to first use.

Keep product in original packaging until ready to use.

Heartworm Prevention:

For the prevention of heartworm disease, NexGard COMBO should be administered once a month year-round. At a minimum, administration of NexGard COMBO should start at least 1 month before the cat's first expected exposure to mosquitoes and monthly thereafter until at least 3 months after the cat's last seasonal exposure to mosquitoes. If a dose is missed and a 30-day interval between doses is exceeded, administer NexGard COMBO immediately and resume the monthly dosing schedule. Treatment with fewer than 3 monthly doses may not provide complete heartworm prevention. When replacing another monthly heartworm preventive product in a heartworm prevention program, the first treatment with NexGard COMBO should be given within one month of the last dose of the former medication. At the discretion of the veterinarian, cats older than 6 months of age may be tested to determine the presence of existing heartworm infection before treatment with NexGard COMBO. Cats already infected with adult heartworms can be given NexGard COMBO monthly to prevent further infections.

Flea Treatment and Prevention:

For the treatment and prevention of flea infestations, the use of NexGard COMBO may begin at any time of year. NexGard COMBO should be administered year-round at monthly intervals or begin at least one month before fleas become active. However, an environmental infestation may persist for a short time after beginning treatment with NexGard COMBO because of the development of adult fleas from eggs that were laid prior to the initiation of treatment.

Tick Treatment and Control:

For the treatment and control of infestations with Ixodes scapularis and Amblyomma americanum, the use of NexGard COMBO may begin at any time of year. NexGard COMBO should be administered year-round at monthly intervals or begin at least one month before the ticks become active.

Treatment and Control of Roundworms, Hookworms, and Tapeworms: NexGard COMBO provides treatment and control of roundworms (adult and fourth stage larval Toxocara cati), hookworms (adult and fourth stage larval Ancylostoma tubaeforme; adult Ancylostoma braziliense), and tapeworms (Dipylidium caninum). For the treatment of hookworm, roundworms and tapeworm infections, NexGard COMBO should be administered once as a single dose. Monthly use of NexGard COMBO will control any subsequent infections. Cats may be exposed to and can become infected with roundworms, hookworms, and tapeworms throughout the year, regardless of season or climate.

Contraindications:

There are no known contraindications for the use of Nexgard Combo.

Human Warnings:

Not for human use. Keep this and all drugs out of sight and reach of children.

Avoid direct contact with application site for 4 hours or until visibly dry.

This product may act as a mild to moderate eye irritant.

Keep product in the original packaging until use. Wash hands after product administration. If the product accidentally gets into the eyes, rinse thoroughly with water. If wearing contact lenses, flush the eyes first with water and then remove the lenses and continue to flush thoroughly with water. In case of accidental ingestion, or if skin or eye irritation occurs, contact a poison control center or physician for treatment advice.

Precautions:

Esafoxolaner, one of the ingredients in NexGard COMBO, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in cats receiving isoxazoline class drugs, even in cats without a history of seizures. Use with caution in cats with a history of seizures or neurologic disorders.

Do not administer orally. Cats may salivate excessively if NexGard COMBO is accidentally administered orally or is ingested through licking/grooming the application site.

The safety of NexGard COMBO has not been tested in breeding, pregnant, or lactating cats.

The safety of NexGard COMBO has not been tested in kittens less than 8 weeks of age or weighing less than 1.8 lbs (0.8 kg).

Storage Information:

Store at 59° – 86°F (15° – 30° C). Brief periods up to 104° F (40° C) are permitted. Protect from light.