Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
5-in-1 Monthly Flea, Heartworm & Intestinal Parasite Protection for Small Dogs (5–10 lbs)
Product Description
Trifexis Chewable Tablets (Magenta Box) are a prescription, once-monthly oral treatment for dogs and puppies weighing between 5 and 10 pounds. Each beef-flavored tablet brings together Spinosad and Milbemycin Oxime to fight five different parasites in one monthly dose. It wipes out fleas quickly, guards against heartworm disease, and clears adult hookworm, roundworm, and whipworm infections all in one go. Dogs that have crossed the 8-week mark and weigh 5 pounds or above can be given this tablet.
Benefits
- Kills Fleas Fast: Spinosad gets to work on fleas within 30 minutes of the tablet being given, hitting complete kill effectiveness by the 4-hour mark.
- Prevents Heartworm Disease: Milbemycin Oxime targets the L3 and L4 larval stages of Dirofilaria immitis before they develop into adult heartworms in small dogs.
- Controls Flea Infestations: Wipes out existing flea infestations and blocks new ones from forming; field studies recorded flea reductions of 98% to 99.8% across three monthly treatments.
- Treats Roundworms: Delivers 90% or greater effectiveness against adult Toxocara canis and Toxascaris leonina roundworm infections in small dog breeds.
- Treats Hookworms: Clears adult Ancylostoma caninum infections, a parasite that can lead to significant blood loss even in small, otherwise healthy dogs.
- Treats Whipworms: Also handles adult Trichuris vulpis infections, a level of cover that many heartworm-only products simply do not include.
- Easy to Administer: The beef-flavored tablet can be offered by hand, mixed into a meal, or hidden in a treat, keeping monthly dosing straightforward for small dog owners.
- No Drying Time Needed: There is no waiting period after giving this tablet; small dogs can be picked up and played with straight after their monthly dose.
- Trusted by Dog Owners: Close to ten years in use and upward of 272 million doses confirm just how reliable this parasite tablet has proven to be.
Ingredients
Active Ingredients (per tablet, 5–10 lb dogs)
Spinosad 140 mg, Milbemycin Oxime 2.3 mg
Other Ingredients
The beef flavoring in this tablet is derived from artificial beef flavoring made using pork-based proteins and hydrolyzed soy, not from real beef.
How to Use
Dosage & Administration Instructions
- Prescription Required: This FDA-approved tablet can only be obtained through a licensed veterinarian with a valid veterinarian-client-pet relationship firmly in place.
- Monthly Oral Dose: Give one full chewable tablet by mouth once a month, sticking to roughly the same date each time for unbroken year-round protection.
- Always Give With Food: This tablet must be given alongside a meal every single time; skipping food can reduce how well the tablet works in your dog's body.
- How to Offer the Tablet: Hand it over directly, stir it into food, or tuck it inside a treat; it is specially made to appeal to small dogs at mealtime.
- Watch After Dosing: Stay close to your dog for one hour after giving the tablet; follow up with a complete fresh dose straight away if the stomach does not hold it down.
- Minimum Dose: Every Magenta Box tablet delivers at least 13.5 mg/lb (30 mg/kg) Spinosad and 0.2 mg/lb (0.5 mg/kg) Milbemycin Oxime per monthly application.
- Seasonal Use: For seasonal dosing, begin within one month of the first mosquito exposure and carry on for at least three months after the mosquito season wraps up.
- Missed Dose: If the time between doses goes beyond 30 days, give the tablet with a meal right away and continue the regular monthly schedule from that point onward.
- Minimum Age and Weight: Dogs that have turned 8 weeks old and reached a body weight of at least 5 pounds can be given this tablet without concern.
Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any medication for your pet.
Additional Information
Precautions
- Heartworm Screening First: A heartworm test with the vet should be done before the very first dose, as adult heartworm infections already present in the body are beyond what this product handles.
- Not for Adult Heartworms: This product has no effect on adult Dirofilaria immitis; dogs that test positive should complete adulticide treatment before being started on this tablet.
- Three Doses for Full Cover: Giving fewer than three consecutive monthly doses after the last mosquito exposure may leave small dogs without complete heartworm protection.
- Avoid Use With Ivermectin: Serious reactions have been documented when Spinosad and ivermectin are used at the same time; tell your vet about every medication your dog is currently on.
- Dogs Only: This product was built exclusively for dogs and must never be given to cats under any circumstances.
- High Microfilariae Counts: Small dogs carrying a high number of circulating microfilariae may show brief, mild reactions like laboured breathing, drooling, or low energy after receiving milbemycin oxime.
- Breeding Dogs: Always check with your vet before giving this product to females intended for breeding; safety in male breeding dogs has not been formally looked into.
- Fleas After Dosing: Fleas seen within a month of dosing have hatched from pupae already sitting in the environment; they will be killed before they ever get to reproduce.
- Worms in Stool: Intestinal worms turning up in your small dog's stool after dosing is a perfectly normal sign that the product is doing exactly what it is supposed to do.
Possible Side Effects
- Vomiting: The most frequently reported reaction, and more common in puppies under 14 weeks; give a full replacement tablet right away if it happens in the first hour.
- Digestive Upset: Loose stools, a drop in appetite, or heavier-than-usual drooling have been reported in some small dogs after taking their monthly tablet.
- Low Energy: Some dogs show a clear drop in their usual activity level and tend to sleep more in the period following their monthly dose.
- Skin Reactions: Itching, patches of skin redness, and areas of localised skin inflammation have been seen in some dogs after receiving this product.
- Neurological Reactions: Trembling, shaking, poor coordination, and seizures have been noted after the product came to market; call your vet immediately if any of these show up.
- Severe Allergic Reaction: Though uncommon, sudden facial swelling, hives, very pale gums, cold limbs, or collapse all demand immediate emergency veterinary attention without delay.
Storage Information
- Room Temperature Storage: Find a consistent indoor spot that sits between 68°F and 77°F (20°C to 25°C) and keep this product there at all times.
- Safe Storage Practice: Keep this prescription tablet well out of reach of children and other household animals to remove any risk of accidental ingestion.
Shipping & Return
We offer ground, express, and priority delivery; see our shipping policy for details.
For return instructions or product concerns, please refer to our detailed refund policy.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Frequently Asked Questions
Q1: What parasites does Trifexis (Magenta Box) protect small dogs against?
Ans: Trifexis (Magenta Box) tackles five parasites in one monthly tablet: it kills fleas, prevents heartworm disease, and treats adult hookworms, roundworms, and whipworms. It covers the most common parasites small dogs encounter on a daily basis but does not include tick prevention.
Q2: How quickly does Trifexis start killing fleas on small dogs?
Ans: Spinosad, one of the two active ingredients, begins working on fleas within 30 minutes of the tablet being swallowed and reaches full kill effectiveness within 4 hours. Fleas are taken out before they ever get the opportunity to produce eggs, cutting the flea cycle short on your small dog.
Q3: My small dog vomited shortly after taking Trifexis. What should I do?
Ans: Give a complete replacement tablet alongside food right away if vomiting happens within the first hour. Pairing the tablet with a full meal each time helps reduce the likelihood of it occurring again. Reach out to your vet if the vomiting keeps going or seems particularly severe.
Q4: Can Trifexis be given to a small dog that already has heartworms?
Ans: No. This product does not act against adult heartworms and is not cleared for that purpose. Every dog must be screened before the first dose is given. Dogs that test positive should go through adulticide treatment first before this tablet is introduced as a monthly preventive.
Q5: Does Trifexis contain anything that could affect small dogs with food sensitivities?
Ans: The beef flavoring in this tablet is made from artificial beef flavoring using pork-based proteins and hydrolyzed soy, not actual beef. Dogs with known soy or pork sensitivities should be assessed by a vet before starting treatment. This product does not contain gluten.