Legend (Hyaluronate Sodium) Injectable Solution, 4 ml

Legend (Hyaluronate Sodium) Injectable Solution, 4 ml

LEGEND Injectable Solution is indicated in the treatment of joint dysfunction of the carpus or fetlock in horses due to non-infectious synovitis associated with equine osteoarthritis. Equine osteoarthritis can happen in any age and any discipline due to everyday wear and tear. It is permanent and can lead to early retirement and quality-of-life issues in horses.

The active ingredient in LEGEND, hyaluronic acid (HA), decreases the presence of inflammatory mediators in the joint, improves synovial fluid quality, and reduces the degree of lameness. These improvements are seen whether LEGEND is administered by intravenous (I.V.) or intra-articular (I.A.) injection. LEGEND hyaluronate sodium injectable is sterile, pyrogen-free and FDA-approved.

Benefits 

• Safe and efficacious

• 90% of cases treated I.V. judged to have excellent to good overall clinical improvement¹

• 96% of horses treated intra-articularly were judged to have excellent to good overall clinical improvement¹

• Improvement can be seen after one dose

• Provides multi-modal approach against the cycle of inflammation and lameness

• Stimulates endogenous hyaluronic acid production²

• Creates a physical barrier to exclude inflammatory mediators³

• Decreases the presence of inflammatory mediators⁴

• Easy to use I.V. administration for when intra-articular administration is not practical or desired

Recommended Dosage

Use as directed by your veterinarian.

LEGEND 4 mL (40 mg) can be injected intravenously only at a dosage of 4 mL. Intravenous treatment may be repeated at weekly intervals for a total of 3 treatments. 

Important Safety Information

The safety of LEGEND 4 mL has not been evaluated in breeding stallions or in breeding, pregnant or lactating mares. The following adverse reactions have been reported following intravenous use of LEGEND 4 mL Injectable Solution: occasional depression, lethargy, and fever.

The following adverse reactions have been reported following use of LEGEND Injectable Solution: Following intravenous use: occasional depression, lethargy, and fever. Following intra-articular (LEGEND Injectable Solution — 2 mL only) use: lameness, joint effusion, joint or injection site swelling and joint pain.

Not for use in humans. Keep this and all other drugs out of reach of children. Strict aseptic techniques should be observed when administering by intra-articular injection.

Storage Instructions

Store at or below 77° F (25° C). Brief excursions to 104° F (40° C) are permitted.

All prescription items are Non-Refundable and Non-Returnable.