Diroban Injection for Dogs 50mg (5 vials)

Zoetis SKU: PCP-012MER-MEISP

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Diroban for Dogs: Effective Heartworm Treatment

Diroban is an injectable solution containing melarsomine dihydrochloride, specifically formulated to treat heartworm disease (Dirofilaria immitis) in dogs. This medication targets and eliminates both immature and mature adult heartworms, addressing the root cause of the infection.

What Are the Benefits of Diroban Injection for Dogs?

  • Targeted Heartworm Elimination: Effectively kills immature (4-month-old, stage L5) to mature adult heartworms, ensuring comprehensive treatment.
  • Proven Efficacy: Demonstrated success in treating stabilized Class 1, 2, and 3 heartworm disease, improving your dog's health and longevity.
  • Veterinarian-Administered: Ensures precise dosing and monitoring, enhancing safety and effectiveness.

How Is Diroban Administered to Dogs?

  1. Dosage and Administration:
    • Injection Site: Administered by deep intramuscular injection in the lumbar (epaxial) muscles (L3–L5) only.
    • Dosage Schedule:
      • Two-Injection Protocol: 2.5 mg/kg body weight administered twice, 24 hours apart.
      • Three-Injection Protocol: 2.5 mg/kg body weight administered once, followed by two injections 24 hours apart one month later.
    • Note: The three-injection protocol is recommended for increased efficacy and safety.
  2. Post-Treatment Care:
    • Exercise Restriction: Limit your dog's activity to reduce the risk of complications from dying worms.
    • Monitoring: Observe for any adverse reactions and consult your veterinarian if concerns arise.

What Are the Ingredients in Diroban Injection?

  • Active Ingredient:
    • Melarsomine dihydrochloride (50 mg per vial).
  • Inactive Ingredients:
    • Glycine USP (33.75 mg per vial).

Are There Any Side Effects of Diroban Injection for Dogs?

Common side effects may include:

  • Injection site reactions (pain, swelling, tenderness).
  • Coughing or gagging.
  • Depression or lethargy.
  • Loss of appetite.
  • Fever.
  • Lung congestion.
  • Vomiting.

If any severe or concerning reactions occur, contact your veterinarian immediately.

What Precautions Should Be Taken When Using Diroban ?

  • Not for Use in Severe Cases: Do not use in dogs with very severe (Class 4) heartworm disease.
  • Proper Administration: Ensure injection is deep intramuscular in the lumbar (epaxial) muscles (L3–L5) only; avoid superficial injection or leakage.
  • Human Safety: Avoid human exposure; consult a physician in cases of accidental exposure.
  • Breeding Animals: Safety in breeding, pregnant, or lactating dogs has not been determined.

Diroban Frequently Asked Questions

What is Diroban used for?

Diroban is used to treat heartworm disease in dogs by eliminating immature and mature adult heartworms.

Can Diroban be used in cats?

No, Diroban is formulated specifically for dogs and should not be used in cats.

How long does the treatment process take?

The treatment protocol varies but typically involves multiple injections over a period of 1 to 2 months, followed by a recovery phase with exercise restriction.

Is exercise restriction necessary after treatment?

Yes, limiting activity post-treatment is crucial to prevent complications from dying heartworms.

What should I do if my dog shows side effects after treatment?

Contact your veterinarian promptly to discuss any adverse reactions and receive appropriate care instructions.

Additional Resources

For more information on heartworm disease and treatment options, consider the following reputable sources:

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

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