Clavacillin (Amoxicillin Trihydrate/Clavulanate Potassium) Tablets, 375mg

Broad-Spectrum Antibiotic Tablets for Dogs with Resistant Infections

Product Description

Clavacillin 375 mg Tablets are a veterinary prescription antibiotic formulated with amoxicillin and clavulanate potassium to treat susceptible bacterial infections in dogs. This combination extends antibacterial coverage against β-lactamase–producing organisms, making it effective for skin, soft tissue, and periodontal infections. The tablets are rapidly absorbed and widely distributed in body tissues for reliable therapeutic action.

Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.

Benefits

• Broad Coverage: Combines amoxicillin with clavulanate to extend antibacterial activity against β-lactamase–producing and non-producing aerobic and anaerobic bacteria.
• Effective Infection Treatment: Indicated for treating canine skin infections, wounds, abscesses, cellulitis, and periodontal disease caused by susceptible bacterial strains.
• Rapid Absorption: Stable in gastric acid and quickly absorbed, producing therapeutic concentrations in serum, urine, and tissues after oral administration.
• Enhanced Resistance Protection: Clavulanic acid inhibits β-lactamase enzymes, helping overcome bacterial resistance that reduces the effectiveness of standard penicillin antibiotics.
• Reliable Tissue Distribution: Active ingredients diffuse into most body tissues and fluids, supporting consistent antibacterial activity at infection sites.

Variants

375 mg Tablets

Ingredients

Composition Table

How to Use

Recommended Dosage Chart

Dosage & Administration Instructions

• Veterinary Prescription: This medication is only for use by or on the order of a licensed veterinarian.
• Weight-Based Dosing: Give the medication based on your pet’s body weight and your veterinarian's instructions to ensure safe and effective treatment.
• Treatment Duration: Keep up the treatment for the suggested time or at least 48 hours after symptoms go away, unless your veterinarian advises otherwise.
• Response Monitoring: If there is no improvement in the recommended timeframe, stop the treatment and talk to your veterinarian for a reassessment.
• Culture Testing: It’s best to perform bacterial culture and susceptibility testing before starting treatment to confirm the right antibiotic choice.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Allergy Risk: Do not use in animals that are known to be sensitive to penicillins or cephalosporins because of the risk of allergic reactions.
• Pregnancy Safety: Safety in pregnant or breeding animals has not been confirmed, so it's important to consult a vet before giving this medication.
• Secure Storage: Keep tablets away from children and pets to avoid accidental exposure or overdose.
• Treatment Evaluation: Obtain culture samples before treatment when possible and reevaluate therapy based on clinical response and results.

Possible Side Effects

• Digestive Upset: Vomiting and diarrhea are among the most frequently reported adverse reactions in dogs and cats receiving treatment.
• Reduced Appetite: Some pets may experience anorexia or decreased appetite during treatment with amoxicillin and clavulanate tablets.
• Lethargy Signs: Lethargy or decreased activity levels have been reported in post-approval adverse event monitoring data.
• Allergic Reaction: Allergic responses may occur due to the penicillin component, requiring veterinary attention and possible emergency treatment.

Storage Information

• Room Temperature: Store tablets at controlled room temperature between 20°C and 25°C to maintain stability and effectiveness.
• Foil Protection: Keep tablets in original foil packaging until ready to use to protect from moisture and environmental exposure.
• Secure Location: Store medication in a safe location away from pets, children, and other animals to prevent accidental ingestion.
  
  

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy. 

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Clavacillin 375 mg used for in dogs?

Ans: Clavacillin 375 mg is indicated for treating susceptible bacterial infections in dogs, including soft tissue and skin infections such as wounds, abscesses, cellulitis, and periodontal disease. It works against both β-lactamase–producing and non-producing bacteria when prescribed by a veterinarian.

Q2: How does Clavacillin differ from regular amoxicillin for pets?

Ans: Clavacillin combines amoxicillin with clavulanate potassium, a β-lactamase inhibitor that protects the antibiotic from bacterial enzyme destruction. This combination extends antimicrobial activity to resistant bacteria that standard amoxicillin alone may not effectively treat in veterinary infections.

Q3: How long should dogs take Clavacillin tablets?

Ans: Treatment usually lasts from 5 to 7 days or at least 48 hours after symptoms go away. More serious infections, such as deep pyoderma, may need up to 21 days of treatment. However, the total treatment time should not go beyond 30 days unless a veterinarian advises otherwise.

Q4: Can Clavacillin cause side effects in dogs or cats?

Ans: Reported side effects include vomiting, diarrhea, decreased appetite, and lethargy. Because the medication contains a penicillin derivative, allergic reactions are also possible. Pet owners should contact their veterinarian if any unusual symptoms or reactions occur during treatment.

Q5: Is Clavacillin safe for all pets?

Ans: Clavacillin should not be used in animals with known hypersensitivity to penicillins or cephalosporins. The safety has not been determined in breeding and pregnant animals. The medication must only be used under veterinary supervision to ensure appropriate dosing and monitoring.