Senergy Topical Solution for Dogs, 85.1-130 lbs, (Plum Box)

Virbac SKU: 50085-1

104,00 lei

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1 Doses (1-mos. supply)
3 Doses (3-mos. supply)
6 Doses (6-mos. supply)
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Senergy Topical Solution for Dogs, 85.1-130 lbs

Senergy is a convenient topical parasiticide for your pet pal that is designed to help prevent heartworm disease while killing adult fleas and deterring flea eggs from hatching for one month. It may also be used to aid in the treatment and control of ear mite infestations as well as roundworm and hookworm infections.

  • Control fleas, heartworms, ear mites, roundworms, and hookworms for one month.
  • Kills adult fleas and prevents flea eggs from hatching.
  • Treats and controls ear mite, hookworm, and roundworm infestations.
  • Easy topical application.


Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.

Dosage and Administration:

The recommended minimum dose is 2.7 mg of selamectin per pound (6 mg/kg) of body weight. Administer the entire contents of a single dose tube (or two tubes used in combination for dogs weighing over 130 pounds) of SENERGY topically by the following tables.

Cats (lb) Package Color mg per tube Potency (mg/mL) Administered volume (mL)
Up to 5 Mauve 15 mg 60 0.25
5.1-15 Blue 45 mg 60 0.75
15.1-22 Taupe 60 mg 60 1.0

For cats over 22 lbs use the appropriate combination of tubes.

Dogs (lb) Package Color mg per tube Potency (mg/mL) Administered volume (mL)
Up to 5 Mauve 15 mg 60 0.25
5.1-10 Lavender 30 mg 120 0.25
10.1-20 Brown 60 mg 120 0.5
20.1-40 Red 120 mg 120 1.0
40.1-85 Teal 240 mg 120 2.0
85.1-130 Plum 360 mg 120 3.0

For dogs over 130 lbs use the appropriate combination of tubes. Recommended for use in dogs 6 weeks of age and older and in cats 8 weeks of age and older.


A veterinarian or veterinary technician should demonstrate or instruct the pet owner regarding the appropriate technique for applying SENERGY topically to dogs and cats before first use. Remove the tube from the package and hold it upright with the lot and expiration at the bottom. Bend the tip back until it snaps off. To administer the product, part the hair on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the tube on the skin and squeeze the tube 3 or 4 times to empty its entire contents directly onto the skin in one spot. Keeping the tube squeezed, drag it away from the liquid and lift it to remove. Check the tube to ensure that it is empty. Do not massage the product into the skin. Due to alcohol content, do not apply to broken skin. Avoid contact between the product and fingers. Do not apply when the haircoat is wet. Bathing or shampooing the dog 2 or more hours after treatment will not reduce the effectiveness of SENERGY against fleas or heartworm. Bathing or shampooing the cat 2 hours after treatment will not reduce the effectiveness of SENERGY against fleas. Bathing or shampooing the cat 24 hours after treatment will not reduce the effectiveness of SENERGY against heartworm. Stiff hair, clumping of hair, hair discoloration, or a slight powdery residue may be observed at the treatment site in some animals. These effects are temporary and do not affect the safety or effectiveness of the product. Discard empty tubes in your ordinary household refuse.

Flea Control in Dogs and Cats

For the prevention and control of flea infestations, SENERGY should be administered at monthly intervals throughout the flea season, starting one month before fleas become active. In controlled laboratory studies ›98% of fleas were killed within 36 hours. Results of clinical field studies using selamectin monthly demonstrated ›90% control of flea infestations within 30 days of the first dose. Dogs and cats treated with selamectin, including those with pre-existing flea allergy dermatitis, showed improvement in clinical signs associated with fleas as a direct result of eliminating the fleas from the animals and their environment.

If the dog or cat is already infested with fleas when the first dose of selamectin is administered, adult fleas on the animal are killed and no viable fleas hatch from eggs after the first administration. However, an environmental infestation of fleas may persist for a short time after beginning treatment with selamectin because of the emergence of adult fleas from pupae.

Heartworm Prevention in Dogs and Cats

For the prevention of heartworm disease, SENERGY must be administered every month. SENERGY may be administered year-round or within one month after the animal's first exposure to mosquitoes and monthly after that until the end of the mosquito season. The final dose must be given within one month after the last exposure to mosquitoes. If a dose is missed and a monthly interval between dosing is exceeded then immediate administration of SENERGY and resumption of monthly dosing will minimize the opportunity for the development of adult heartworms. When replacing another heartworm preventive product in a heartworm disease prevention program, the first dose of SENERGY must be given within a month of the last dose of the former medication.

Selamectin, the active ingredient in SENERGY, is a macrocyclic lactone compound. These compounds effectively prevent the development of adult heartworms when administered to dogs and cats within one month of exposure to infective (L3) Dirofilaria immitis larvae. However, the efficacy of macrocyclic lactones decreases below 100% in dogs if first administered ›2 months after exposure to infective larvae. Thus, in heartworm endemic regions, delaying initiation of heartworm prevention using SENERGY beyond 2 months of first exposure to infective larvae (e.g., starting puppies and kittens at ›8 weeks of age), or gaps of ›2 months in the administration of SENERGY during periods of heartworm transmission, increases the risk of the animal acquiring heartworms. Animals with unknown heartworm history that test negative for heartworms before the initiation of SENERGY may be harboring pre-patent infections at the time SENERGY was started. Testing such animals 3-4 months after initiation of SENERGY would be necessary to confirm their negative heartworm status.

At the discretion of the veterinarian, cats ≥6 months of age may be tested to determine the presence of existing heartworm infections before beginning treatment with SENERGY. Cats already infected with adult heartworms can be given SENERGY monthly to prevent further infections.


Store below 25°C (77°F).


What is the most important thing I should know about Senergy?
Senergy is indicated for the treatment and prevention of flea infestations, roundworms, hookworms, heartworms, and ear mites. Senergy requires a prescription from your veterinarian. Senergy is for dogs 6 weeks of age or older and cats 8 weeks of age or older.

What should I discuss with my veterinarian before giving Senergy to my pet?
Let your veterinarian know if your pet has any underlying health conditions or takes any other medications, or if they have had an adverse reaction to a parasiticide in the past.

What are the potential side effects of Senergy?
Following treatment with selamectin, transient localized alopecia with or without inflammation at or near the site of application was observed in approximately 1% of 691 treated cats. Other signs observed rarely (≤0.5% of 1743 treated cats and dogs) included vomiting, loose stool or diarrhea with or without blood, anorexia, lethargy, salivation, tachypnea, and muscle tremors. In addition to the aforementioned clinical signs that were reported, in pre-approval clinical trials, there have been reports of pruritus, urticaria, erythema, ataxia, fever, and rare reports of death. There have also been rare reports of seizures in dogs.

What happens if I miss giving a dose of Senergy?
Administer the missed dose as soon as you remember and contact your veterinarian.

What happens if I overdose my pet on Senergy?
Contact your veterinarian if you administer more than the prescribed amount of Senergy.

What should I avoid while giving Senergy to my pet?
Do not use in sick, debilitated, or underweight animals. Do not massage the product into the skin. Due to alcohol content, do not apply to broken skin. Avoid contact between the product and fingers. Do not apply when the haircoat is wet.

What other drugs will affect Senergy?
Let your veterinarian know about any medications your pet takes, including medications available without a prescription to ensure that they can be taken safely with Senergy.