Revolution for Kittens & Puppies under 5 lbs
Revolution is a medication that is applied directly on your furry friend's skin to protect them from biting critters. When applied every 30 days, Revolution protects against heartworms, fleas, and ear mites. It's also effective in preventing and treating roundworms and hookworms in kittens and sarcoptic mange and American dog tick infestations in puppies.
Revolution has a 20+ year history working to protect tens of millions of pets. It has been tested safe in over 100 different pure and mixed breeds of healthy dogs, including:
- Pregnant and lactating females
- Breeding males and females
- Puppies six weeks of age and older, with no minimum weight
- Avermectin-sensitive collies
- Heartworm-positive dogs
Revolution is an FDA-approved medication that, when applied topically, has systemic effects, treating both internal and external parasites.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.
INDICATIONS:
Revolution is recommended for use in dogs six weeks of age or older and cats eight weeks of age and older for the following parasites and indications:
Dogs:
Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. Revolution also is indicated for the treatment and control of sarcoptic mange (Sarcoptes scabiei) and for the control of tick infestations due to Dermacentor variabilis.
Cats:
Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. Revolution is also indicated for the treatment and control of roundworm (Toxocara cati) and intestinal hookworm (Ancylostoma tubaeforme) infections in cats.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.
Possible Side Effects
The most common is hair loss at the site of application with or without inflammation (redness, flaking) in cats. Other side effects reported in cats and dogs include vomiting, diarrhea with or without blood, anorexia (decreased appetite), lethargy (sluggishness), salivation, rapid breathing, pruritus (itching), urticaria (welts, hives), erythema (skin redness), ataxia (incoordination), fever and rare instances of death. There have also been rare reports of seizures in dogs. If you have additional questions about possible side effects, talk to your veterinarian.
DOSAGE AND ADMINISTRATION:
The recommended minimum dose is 2.7 mg selamectin per pound (6 mg/kg) of body weight.
Administer the entire contents of a single dose tube (or two tubes used in combination for dogs weighing over 130 pounds) of Revolution topically in accordance with the following tables.
Dogs (lb) | Package color | mg per tube | Potency (mg/mL) | Administered volume (mL) |
---|---|---|---|---|
Up to 5 | Mauve | 15 mg | 60 | 0.25 |
5.1 - 10 | Purple | 30 mg | 120 | 0.25 |
10.1 - 20 | Brown | 60 mg | 120 | 0.5 |
20.1 - 40 | Red | 120 mg | 120 | 1.0 |
40.1 - 85 | Teal | 240 mg | 120 | 2.0 |
85.1 - 130 | Plum | 360 mg | 120 | 3.0 |
For dogs over 130 lbs use the appropriate combination of tubes.
Recommended for use in dogs 6 weeks of age and older and in cats 8 weeks of age and older.
A veterinarian or veterinary technician should demonstrate or instruct the pet owner regarding the appropriate technique for applying Revolution topically to dogs and cats prior to first use.
Firmly press the cap down to puncture the seal on the Revolution tube; a clicking sound will confirm that the cap has successfully punctured the seal. Remove the cap and check to ensure that the tip of the tube is open. To administer the product, part the hair on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the tube on the skin and squeeze the tube 3 or 4 times to empty its entire contents directly onto the skin in one spot. Keeping the tube squeezed, drag it away from the liquid and lift to remove. Check the tube to ensure that it is empty. Do not massage the product into the skin. Due to alcohol content, do not apply to broken skin. Avoid contact between the product and fingers. Do not apply when the haircoat is wet. Bathing or shampooing the dog 2 or more hours after treatment will not reduce the effectiveness of Revolution against fleas or heartworm. Bathing or shampooing the cat 2 hours after treatment will not reduce the effectiveness of Revolution against fleas. Bathing or shampooing the cat 24 hours after treatment will not reduce the effectiveness of Revolution against heartworm. Stiff hair, clumping of hair, hair discoloration, or a slight powdery residue may be observed at the treatment site in some animals. These effects are temporary and do not affect the safety or effectiveness of the product. Discard empty tubes in your ordinary household refuse.
Flea Control in Dogs and Cats
For the prevention and control of flea infestations, Revolution should be administered at monthly intervals throughout the flea season, starting one month before fleas become active. In controlled laboratory studies ›98% of fleas were killed within 36 hours. Results of clinical field studies using Revolution monthly demonstrated ›90% control of flea infestations within 30 days of the first dose. Dogs and cats treated with Revolution, including those with pre-existing flea allergy dermatitis, showed improvement in clinical signs associated with fleas as a direct result of eliminating the fleas from the animals and their environment.
If the dog or cat is already infested with fleas when the first dose of Revolution is administered, adult fleas on the animal are killed and no viable fleas hatch from eggs after the first administration. However, an environmental infestation of fleas may persist for a short time after beginning treatment with Revolution because of the emergence of adult fleas from pupae.
Heartworm Prevention in Dogs and Cats
For the prevention of heartworm disease, Revolution must be administered on a monthly basis. Revolution may be administered year-round or at least within one month after the animal’s first exposure to mosquitoes and monthly thereafter until the end of the mosquito season. The final dose must be given within one month after the last exposure to mosquitoes. If a dose is missed and a monthly interval between dosing is exceeded then immediate administration of Revolution and resumption of monthly dosing will minimize the opportunity for the development of adult heartworms. When replacing another heartworm preventive product in a heartworm disease prevention program, the first dose of Revolution must be given within a month of the last dose of the former medication.
Selamectin, the active ingredient in Revolution, is a macrocyclic lactone compound. These compounds effectively prevent the development of adult heartworms when administered to dogs and cats within one month of exposure to infective (L3) Dirofilaria immitis larvae. Efficacy of macrocyclic lactones decreases below 100% in dogs, however, if first administered ›2 months after exposure to infective larvae. Thus, in heartworm endemic regions, delaying initiation of heartworm prevention using Revolution beyond 2 months of first exposure to infective larvae (e.g., starting puppies and kittens at ›8 weeks of age), or gaps of ›2 months in the administration of Revolution during periods of heartworm transmission, increases the risk of the animal acquiring heartworms. Animals with unknown heartworm history that test negative for heartworms prior to the initiation of Revolution may be harboring pre-patent infections at the time Revolution was started. Testing such animals 3-4 months after initiation of Revolution would be necessary to confirm their negative heartworm status.
At the discretion of the veterinarian, cats ≥6 months of age may be tested to determine the presence of existing heartworm infections before beginning treatment with Revolution. Cats already infected with adult heartworms can be given Revolution monthly to prevent further infections.
Ear Mite Treatment in Dogs and Cats
For the treatment of ear mite (O. cynotis) infestations in dogs and cats, Revolution should be administered once as a single topical dose. A second monthly dose may be required in some dogs. Monthly use of Revolution will control any subsequent ear mite infestations. In the clinical field trials ears were not cleaned, and many animals still had debris in their ears after the second dose. Cleansing of the infested ears is recommended to remove the debris.
Sarcoptic Mange Treatment in Dogs
For the treatment of sarcoptic mange (S. scabiei) in dogs, Revolution should be administered once as a single topical dose. A second monthly dose may be required in some dogs. Monthly use of Revolution will control any subsequent sarcoptic mange mite infestations. Because of the difficulty in finding sarcoptic mange mites on skin scrapings, effectiveness assessments also were based on resolution of clinical signs. Resolution of the pruritus associated with the mite infestations was observed in approximately 50% of the dogs 30 days after the first treatment and in approximately 90% of the dogs 30 days after the second monthly treatment.
Tick Control in Dogs
For the control of tick (Dermacentor variabilis) infestations in dogs, Revolution should be administered on a monthly basis. In heavy tick infestations, complete efficacy may not be achieved after the first dose. In these cases, one additional dose may be administered two weeks after the previous dose, with monthly dosing continued thereafter.
Nematode Treatment in Cats
For the treatment and control of intestinal hookworm (A. tubaeforme) and roundworm (T. cati) infections, Revolution should be applied once as a single topical dose.
WARNINGS:
User Safety Warnings
Not for human use. Keep out of the reach of children.
In humans, Revolution may be irritating to skin and eyes.
Reactions such as hives, itching and skin redness have been reported in humans. Individuals with known hypersensitivity to Revolution should use the product with caution or consult a health care professional. Revolution contains isopropyl alcohol and the preservative butylated hydroxytoluene (BHT).
Wash hands after use and wash off any product in contact with the skin immediately with soap and water.
If contact with eyes occurs, then flush eyes copiously with water; if wearing contact lenses, rinse the eyes first then remove contact lenses and continue to rinse for 5-10 minutes and seek medical attention.
In case of ingestion by a human, contact a physician immediately.
The safety data sheet (SDS) provides more detailed occupational safety information. To obtain a SDS contact Zoetis at 1-888-963-8471 or www.zoetisus.com.
Flammable - Keep away from heat, sparks, open flames or other sources of ignition.
Animal Safety Warnings
Do not use in sick, debilitated or underweight animals.
PRECAUTIONS:
Prior to administration of Revolution, dogs should be tested for existing heartworm infections. At the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms. Revolution is not effective against adult D. immitis and, while the number of circulating microfilariae may decrease following treatment, Revolution is not effective for microfilariae clearance.
Hypersensitivity reactions have not been observed in dogs with patent heartworm infections administered Revolution.
FAQ
- Why has my veterinarian prescribed Revolution?
- Revolution has been prescribed by your veterinarian to treat, prevent and/or control the following parasites in your dog or cat:
- Dog Parasites:
- Control and prevention of flea infestation (Ctenocephalides felis)
- Prevention of heartworm disease (Dirofilaria immitis)
- Treatment and control of ear mite infestation (Otodectes cynotis)
- reatment and control of sarcoptic mange (Sarcoptes scabiei)
- Control of the American Dog Tick (Dermacentor variabilis)
- Cat Parasites:
- Control and prevention of flea infestation (Ctenocephalides felis)
- Prevention of heartworm disease (Dirofilaria immitis)
- Treatment and control of ear mite infestation (Otodectes cynotis)
- Treatment and control of intestinal worms
- Roundworm (Toxocara cati)
- Hookworm (Ancylostoma tubaeforme)
- What should I discuss with my veterinarian before Revolution is prescribed?
- Your veterinarian is best suited to discuss and recommend appropriate medications for your dog or cat. It is important to discuss your pet's health history with your veterinarian so he/she can decide if Revolution is right for your animal.
- Revolution should not be used in sick, debilitated or underweight animals.
- Dogs should be tested for heartworm disease prior to giving Revolution. If your dog tests positive for adult heartworms, your veterinarian can recommend appropriate treatment. Dogs infected with adult heartworms can safely be given Revolution.
- If your cat is older than six months of age, your veterinarian may decide to test him/her for heartworm disease before prescribing Revolution. Cats infected with adult heartworms can be given Revolution to prevent further infections.
- What dose of Revolution do I use on my dog or cat?
- Your veterinarian will recommend the appropriate dose for your dog or cat based on your animal's body weight. You should not administer Revolution to dogs younger than 6 weeks of age or cats younger than 8 weeks of age. Revolution is available in eight separate dose strengths for dogs and cats of different weights.
- What should I do if I do not give Revolution on time or miss a dose?
- If you forget to apply a monthly dose of Revolution, immediately apply Revolution, resume monthly applications, and notify your veterinarian.
- What if I administer more than the prescribed amount of Revolution to my dog or cat?
- Contact your veterinarian if you administer more than the prescribed amount of Revolution.
- Can I give my pet a bath after applying Revolution?
- Yes. Bathing or shampooing the dog 2 or more hours after treatment will not reduce the effectiveness of Revolution against fleas or heartworm. Bathing or shampooing the cat 2 hours after treatment will not reduce the effectiveness of Revolution against fleas. Bathing or shampooing the cat 24 hours after treatment will not reduce the effectiveness of Revolution against heartworm
- When can I play with my pet following treatment with Revolution?
- You should avoid contact with application site when wet. You may hold or play with your pet any time after the area on which Revolution was applied is dry.
- Can Revolution be given with other medicines?
- In well-controlled clinical studies, Revolution was used safely in dogs and cats receiving other veterinary products such as vaccines, anthelmintics, antiparasitics, antibiotics, steroids, collars, shampoos and dips. Tell your veterinarian about all medicines you have given your dog or cat in the past, and any medicines that you are planning to use with Revolution. This should include other medicines that you can get without a prescription. Your veterinarian may want to check that all of your dog's or cat's medicines can be given together.
Recommended for the Revolution for Kittens & Puppies under 5 lbs
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