Prascend Pergolide for Horses - 1 mg Tablets

Prascend Pergolide for Horses

Prascend Tablets are a critical solution for managing Pituitary Pars Intermedia Dysfunction (PPID), commonly known as Equine Cushing’s Disease, a condition that affect older horses.

Horses with PPID often exhibit symptoms such as excessive hair growth, muscle wasting, abnormal fat distribution, and increased susceptibility to laminitis. 

If left untreated, these symptoms can severely affect your horse's health and overall well-being.  Prascend, containing pergolide mesylate, is the gold standard for controlling PPID, providing long-term stability and improving the quality of life for affected horses.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.

Benefits of Prascend Tablets 

• Stabilizes ACTH Levels: Prascend effectively normalizes ACTH levels, helping to control the symptoms of PPID and prevent further progression of the disease.
• Reduces Risk of Laminitis: By managing hormonal imbalances, Prascend significantly lowers the risk of laminitis, a painful and potentially debilitating condition in horses.
• Enhances Coat Condition: Regular use of Prascend can lead to a more normal shedding pattern and improved coat condition, reducing the excessive hair growth associated with PPID.
• Improves Energy and Muscle Tone: Horses on Prascend often experience increased energy levels and improved muscle tone, leading to a more active and vibrant lifestyle.
• Long-Term Usability: Safe for long-term use, Prascend provides consistent management of PPID symptoms, allowing horses to live healthier, more comfortable lives.

Subscription and Purchase Information

Buying Options and Discounts: Purchase Prascend Tablets in a convenient 1, 2, 3, and 6-month supply pack. Subscribe for regular shipments to ensure you never miss a dose and enjoy discounts on your purchases.

Order online for hassle-free delivery to your doorstep.

Prascend Ingredients

• Primary Ingredient: Pergolide Mesylate 1 mg per tablet.

Dosage and Administration

• Use as directed by your veterinarian. 
• Administer PRASCEND (pergolide tablets) orally at a starting dose of 2 mcg/kg once daily. 
• Dosage may be adjusted to effect, not to exceed 4 mcg/kg daily. 
• The tablets are scored and the calculated dosage should be provided to the nearest one-half tablet increment.
• See prescribing information for more dosing instructions.

Frequency

• Daily Dosing: Administer one 1 mg tablet per day, or as directed by your veterinarian, to ensure consistent control of ACTH levels.

Consistency

• Regular Monitoring: Consistent administration is key to managing PPID effectively. Regular veterinary check-ups are recommended to monitor your horse’s response to treatment and adjust the dosage if necessary.

Side Effects of Prascend

Prascend Tablets are generally well-tolerated, but as with any medication, there can be side effects. It's important to monitor your horse closely during treatment, especially in the early stages. Here are some potential side effects:

• Decreased Appetite: Some horses may exhibit a reduced desire to eat, particularly when first starting Prascend.
• Lethargy: A decrease in energy levels or increased tiredness can occur, especially during the initial weeks of treatment.
• Digestive Disturbances: Mild digestive issues, such as diarrhea or colic, may arise as the horse adjusts to the medication.
• Behavioral Changes: In some cases, horses may exhibit changes in behavior, including increased anxiety or depression.
• Excessive Drinking and Urination: Prascend can lead to increased thirst and urination in some horses.
• Weight Loss: Although Prascend helps in managing PPID, it may also cause unintended weight loss, particularly if the horse's appetite is affected.
• Laminitis Risk: While Prascend helps manage PPID-related laminitis, some horses may still be at risk, especially if the condition is severe or advanced.

If any of these side effects persist or worsen, it’s important to consult your veterinarian to determine if adjustments to the treatment plan are necessary.

Precautions

• Initial Reactions: Some horses may experience reduced appetite, lethargy, or mild digestive disturbances during the initial weeks of treatment. Consult your veterinarian if these symptoms persist.
• Pregnancy & Lactation: Prascend is not recommended for pregnant or lactating mares. Always consult with your veterinarian before starting treatment.

Warnings

• Dosage Adjustments: Avoid abrupt cessation of Prascend, as this may cause a rebound increase in ACTH levels. Gradual adjustments under veterinary supervision are advised.

Storage

• Proper Storage: Store Prascend tablets in a cool, dry place, away from direct sunlight. Ensure that they are kept out of reach of children and other animals to prevent accidental ingestion.

Shipping & Returns 

Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

FAQs - Pergolide for Horses

Q: What exactly is PPID/Cushing's disease in horses?

A: An endocrine condition impacting the pituitary gland, showing signs of increased thirst and urination, laminitis, and unusually long hair growth.

Q: What is the mechanism of action of this medication?

A: Prascend has pergolide, a type of dopamine agonist that decreases the amount of adrenocorticotropic hormone ACTH, effectively treating symptomatic PPID.

Q: How does Prascend compare to other treatments for PPID?

A: Prascend is the only FDA-approved treatment specifically for PPID in horses, offering superior efficacy in managing symptoms and stabilizing ACTH levels compared to alternative therapies.

Q: Can Prascend be used in conjunction with other medications?

A: Prascend can often be used alongside other medications, but it’s crucial to consult your veterinarian to avoid potential drug interactions.

Q: How long does my horse need to be on Prascend?

A: Horses with PPID typically require lifelong treatment with Prascend. Regular monitoring by your veterinarian will ensure the dosage remains effective over time.

Q: What should I do if my horse shows signs of Prascend intolerance?

A: If your horse exhibits intolerance to Prascend, such as severe appetite loss or behavioral changes, consult your veterinarian immediately to adjust the treatment plan.

Q: Are there dietary considerations for horses on Prascend?

A: Horses on Prascend may benefit from a diet low in non-structural carbohydrates to help manage PPID symptoms more effectively. Consult your veterinarian for tailored dietary advice.

Q: Can Prascend be crushed for easier administration?

A: Yes, Prascend tablets can be crushed and mixed with a small amount of feed to facilitate easier administration, especially for horses that are resistant to taking pills.

Q: How soon should I see improvement in my horse's symptoms?

A: While some improvements, such as changes in coat condition, may be seen within a few weeks, full stabilization of ACTH levels and symptom control may take several months.

Q: What are the signs that Prascend is working?

A: Signs that Prascend is effective include improved coat shedding, increased energy levels, reduced symptoms of laminitis, and overall better health and vitality in your horse.

Q: Is it safe to switch from another PPID medication to Prascend?

A: Transitioning from another PPID treatment to Prascend should be done under veterinary supervision to avoid complications or adverse reactions.

Q: What is the shelf life of Prascend tablets?

A: Prascend tablets generally have a shelf life of two years when stored properly. Always check the expiration date before administering.

Clinical Research

• https://www.tandfonline.com/doi/full/10.2147/VMRR.S74191#d1e737
• https://www.sciencedirect.com/science/article/pii/S0739724020300989