SMZ/TMP (sulfamethoxazole and trimethoprim) Tablets, 800 mg/160 mg

Sulfamethoxazole and Trimethoprim (SMZ/TMP) Tablets for Pets

Sulfamethoxazole and Trimethoprim tablets (SMZ/TMP) are a potent, broad-spectrum antibiotic combination designed to address a wide variety of bacterial infections in pets. These tablets are highly effective in treating infections in the urinary tract, respiratory system, gastrointestinal tract, skin, and other areas where bacterial invasions cause discomfort or health risks.

By combining sulfamethoxazole (a sulfonamide antibiotic) with trimethoprim (a dihydrofolate reductase inhibitor), this medication works synergistically to inhibit bacterial growth, ensuring faster recovery for your furry companions.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

NOTE: For generic medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer. Please note product may arrive in a Hardy Paw Pharmacy vial.

Also Available in :

SMZ/TMP (sulfamethoxazole and trimethoprim) Tablets, 400 mg/80 mg

What Are the Benefits of SMZ/TMP Tablets for Pets?

1. Broad-Spectrum Efficacy: Targets a wide range of bacterial infections, making it suitable for multiple conditions.
2. Dual Action Mechanism: Sulfamethoxazole and trimethoprim work together to disrupt bacterial DNA synthesis, enhancing effectiveness.
3. Versatile Application: Effective in treating infections in various systems, including urinary, respiratory, gastrointestinal, and skin infections.
4. Convenient Administration: Oral tablets can be easily administered with meals for improved compliance.

How to Use Sulfamethoxazole and Trimethoprim Tablets?

Always consult your veterinarian for precise dosage instructions tailored to your pet's condition, weight, and specific infection.

General Guidelines:

• Administer orally with or without food.
• Provide access to fresh water to avoid dehydration during treatment.

What Are the Side Effects of Sulfamethoxazole and Trimethoprim?

While this medication is generally well-tolerated, some pets may experience side effects, including:

• Mild Effects: Decreased appetite, vomiting, diarrhea.
• Severe Effects (less common):
  • Keratoconjunctivitis sicca (dry eye).
  • Acute liver inflammation (jaundice).
  • Fever or hemolytic anemia.
  • Urticaria (hives) and polyarthritis.
  • Facial swelling or cholestasis (gall bladder blockage).
    Monitor your pet for any unusual reactions and contact your veterinarian immediately if symptoms persist or worsen.

What Are the Ingredients in SMZ/TMP Tablets?

• Sulfamethoxazole: A sulfonamide antibiotic that prevents bacterial growth by inhibiting folic acid synthesis.
• Trimethoprim: A dihydrofolate reductase inhibitor that enhances the efficacy of sulfamethoxazole by further disrupting bacterial DNA synthesis.

How to Store Sulfamethoxazole and Trimethoprim Tablets?

• Keep at a controlled room temperature of 68°F to 77°F.
• Store in a secure location away from direct sunlight and moisture.
• Ensure the product is inaccessible to children and pets.

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FAQs - SMZ/TMP (sulfamethoxazole and trimethoprim) Tablets

What is SMZ/TMP (sulfamethoxazole and trimethoprim) Tablets used for?

SMZ/TMP tablets are used to treat bacterial infections in pets, including urinary tract infections, respiratory infections, gastrointestinal issues, skin conditions, and other systemic infections. The combination of sulfamethoxazole and trimethoprim inhibits bacterial growth, effectively eliminating infections and promoting recovery.

Is SMZ/TMP safe for long-term use in pets?

While SMZ/TMP can be used for chronic conditions under veterinary guidance, long-term use may require regular monitoring of your pet's kidney, liver, and blood functions to ensure safety and effectiveness. Always follow your veterinarian's recommendations.

How do SMZ/TMP tablets work in pets?

SMZ/TMP tablets combine two antibiotics, sulfamethoxazole and trimethoprim, to block bacterial DNA synthesis. This dual-action mechanism prevents bacteria from growing and spreading, making it highly effective against a wide range of infections.

Can SMZ/TMP treat skin infections in pets?

Yes, SMZ/TMP is effective against many types of bacterial skin infections in pets, including pyoderma. Its broad-spectrum activity helps clear up infections quickly when used as prescribed.

What precautions should I take if my pet has kidney or liver disease?

Pets with kidney or liver disease may need adjusted doses of SMZ/TMP or alternative treatments. Always inform your veterinarian about your pet’s health history to ensure safe usage of the medication.

Does SMZ/TMP have any dietary restrictions?

SMZ/TMP can be given with or without food. However, providing the medication with a small meal can help minimize stomach upset. Ensure your pet has access to fresh water to stay hydrated during treatment.

Can SMZ/TMP tablets be crushed or split for smaller pets?

Yes, SMZ/TMP tablets can be split or crushed to facilitate dosing for smaller pets. However, always consult your veterinarian for the exact dosage and instructions tailored to your pet’s weight and condition.

How quickly will SMZ/TMP start working in pets?

Most pets start showing improvement within 2-3 days of starting SMZ/TMP treatment. However, it is essential to complete the entire prescribed course to ensure the infection is fully resolved and to prevent antibiotic resistance.

What should I do if my pet misses a dose of SMZ/TMP?

If a dose is missed, give it as soon as you remember. If it’s almost time for the next dose, skip the missed one and continue with the regular schedule. Never double-dose, as this could lead to overdose complications.

Clinical Research:

• MedlinePlus - Sulfamethoxazole and Trimethoprim
• Medscape - Sulfamethoxazole and Trimethoprim Overview
• Wisconsin Department of Health Services - Sulfamethoxazole and Trimethoprim Fact Sheet