Desmopressin Acetate 0.01% Nasal Spray (5 mL)

Desmopressin Acetate Nasal Spray

Desmopressin acetate is prescribed for animals with central diabetes insipidus (a condition that happens when the pituitary glands don't release enough vasopressin). It’s a synthetic replacement for vasopressin, also known as antidiuretic hormone or ADH, which is a hormone produced by a dog’s pituitary gland that helps regulate urine production by the kidneys and the amount of water that the body retains.

Though the FDA has not approved it for veterinary use, vets can prescribe it safely and legally. The drug is available in tablet form, though it’s less common for dogs to take it orally. Vets most often prescribe it in the form of a 10-microgram solution that can be administered nasally or through the eyes. 

All prescription items are Non-Refundable and Non-Returnable.

NOTE: For generic medications, picture displayed may not depict actual product. 

Benefits of Desmopressin Nasal Spray

• Effective Management: Controls symptoms of diabetes insipidus and nocturnal enuresis (bed-wetting).
• Quick Absorption: Provides rapid relief by being absorbed directly through the nasal mucosa.
• Precise Dosage: Ensures accurate delivery of medication, minimizing the risk of side effects.
• Child-Friendly: Safe and effective for pediatric use, helping children manage bed-wetting with ease.
• Convenient Usage: Portable and easy to administer, making it suitable for home or on-the-go use.

Subscription and Purchase Information

Buying Options and Discounts: Purchase Desmopressin Acetate 0.01% Nasal Spray in a convenient 1, 2, 3, and 6-month supply pack. Subscribe for regular shipments to ensure you never miss a dose and enjoy discounts on your purchases.
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Ingredients of Desmopressin Nasal Spray

Desmopressin 0.01% Nasal Spray contains the active ingredient Desmopressin Acetate, a synthetic analog of the natural hormone vasopressin. It also includes inactive ingredients such as sodium chloride, citric acid, and benzalkonium chloride, which help stabilize the solution and ensure its efficacy.

How Desmopressin Nasal Spray Works

Desmopressin works by binding to V2 receptors in the kidneys, increasing water reabsorption and reducing urine production. This action helps to concentrate urine, reducing the frequency and volume of urination, and is particularly beneficial in managing conditions like diabetes insipidus and nocturnal enuresis. By mimicking vasopressin, Desmopressin restores the body's natural water balance.

Dosage and Administration 

Frequency

• Administer as prescribed by your healthcare provider, typically 1-2 times daily.
• For diabetes insipidus, the usual dosage is 10-20 mcg (1-2 sprays) daily.
• For bed-wetting, administer the spray 1 hour before bedtime.

Consistency

• Use the spray at the same time each day to maintain consistent levels of the medication in your body.
• Regular usage ensures optimal management of your condition and reduces the risk of symptoms returning.

Desmopressin Acetate Side Effects 

Precautions

• Monitor sodium levels regularly to prevent hyponatremia (low sodium levels).
• Avoid excessive fluid intake to reduce the risk of water retention and low sodium.

Warnings

• May cause mild side effects such as headaches, nasal congestion, or nausea.
• Severe side effects include symptoms of hyponatremia like confusion, seizures, and severe headaches. Seek immediate medical attention if these occur.

Contraindications

• Do not use if you have a known allergy to Desmopressin or any of the spray's components.
• Not recommended for patients with a history of hyponatremia or heart failure.

Storage 

Store Desmopressin 0.01% Nasal Spray at room temperature, away from direct light and moisture. Keep the bottle tightly closed when not in use. Do not refrigerate. Discard the bottle after 50 sprays or if the expiration date has passed.

Shipping & Returns

Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Top 10 FAQs About Desmopressin Nasal Spray

Q: What is Desmopressin Nasal Spray used for?

A: Desmopressin Nasal Spray is used to treat conditions such as diabetes insipidus and nocturnal enuresis (bed-wetting) by reducing urine production and helping the body retain water.

Q: How soon does Desmopressin Nasal Spray start working?

A: Desmopressin Nasal Spray typically begins working within 1 hour after administration, providing quick relief from symptoms like frequent urination and excessive thirst.

Q: Can Desmopressin Nasal Spray be used in children?

A: Yes, Desmopressin Nasal Spray is safe for pediatric use, especially for treating bed-wetting in children over the age of 6, under the guidance of a healthcare provider.

Q: What should I do if I miss a dose of Desmopressin Nasal Spray?

A: If you miss a dose, take it as soon as you remember unless it’s close to the time of your next dose. Do not double the dose to make up for the missed one.

Q: Is it safe to use Desmopressin Nasal Spray with other medications?

A: Consult your healthcare provider before using Desmopressin with other medications, especially those that may affect electrolyte balance or interact with vasopressin analogs.

Q: How long can I use Desmopressin Nasal Spray?

A: The duration of use depends on your condition and your healthcare provider’s advice. Regular monitoring is required for long-term use to avoid complications.

Q: What are the signs of an overdose of Desmopressin Nasal Spray?

A: Overdose symptoms may include severe headache, confusion, nausea, and seizures due to low sodium levels. Seek emergency medical help if an overdose is suspected.

Q: Can I drink fluids after using Desmopressin Nasal Spray?

A: Limit fluid intake after using the spray to avoid water retention and low sodium levels, which can lead to serious health issues.

Q: How do I store Desmopressin Nasal Spray once opened?

A: Store the spray at room temperature, away from moisture and heat. Keep it tightly closed, and discard it after 50 sprays or once it expires.

Q: Can Desmopressin Nasal Spray be used during pregnancy?

A: Consult your healthcare provider if you are pregnant or planning to become pregnant before using Desmopressin Nasal Spray, as it should only be used if clearly needed.

Clinical Research: 

https://link.springer.com/article/10.1007/s11095-009-9871-9

https://www.sciencedirect.com/science/article/pii/S002235491547279X