NexGard PLUS Chews for Small Dogs 4-8 lbs (Orange Box)

NexGard PLUS Chews for Small Dogs 4-8 lbs

All-in-One Protection Against Fleas, Ticks & Parasites

NexGard PLUS Chews for Dogs 4-8 lbs is an advanced flea, tick, and parasite prevention chew designed specifically for small dogs weighing between 4-8 lbs. This once-a-month, beef-flavored chew provides comprehensive protection against external parasites like fleas and ticks while also preventing deadly internal parasites like heartworms, roundworms, and hookworms.

NexGard PLUS combines three powerful active ingredients—Afoxolaner, Moxidectin, and Pyrantel—to deliver broad-spectrum parasite defense in a convenient, easy-to-administer chew.

If you're looking for an effective small dog flea medicine (4-8 lbs) that does more than just kill fleas and ticks, NexGard PLUS is the trusted choice for all-in-one parasite control.

NexGard PLUS chews are available in different weight ranges to ensure accurate dosing and maximum protection for dogs of all sizes. Choose the right option for your pet:

• NexGard PLUS Chews for Dogs 4-8 lbs – Perfect for extra small dogs needing all-in-one parasite protection. (you are viewing this product)
• NexGard PLUS Chews for Dogs 8.1-17 lbs – Ideal for small breeds requiring flea, tick, and worm prevention.
• NexGard PLUS Chews for Dogs 17.1-33 lbs – Formulated for medium-sized dogs with the same trusted protection.
• NexGard PLUS Chews for Dogs 33.1-66 lbs – Designed for large dogs, offering broad-spectrum defense.
• NexGard PLUS Chews for Dogs 66.1-132 lbs – Provides maximum-strength parasite prevention for extra-large breeds.

Find the perfect NexGard PLUS chew for your dog's weight category and ensure year-round protection against fleas, ticks, heartworms, and intestinal worms.

What Are the Benefits of NexGard PLUS Chews for Small Dogs 4-8 lbs?

1. All-in-One Protection

• Kills fleas and ticks fast, reducing the risk of diseases like Lyme disease.
• Prevents heartworm disease, a life-threatening condition transmitted by mosquitoes.
• Treats and controls roundworms and hookworms, common intestinal parasites in dogs.

2. Fast-Acting & Long-Lasting

• Starts killing fleas within 6 hours and provides month-long protection.
• Prevents re-infestations by disrupting the flea life cycle.

3. Tasty & Easy to Administer

• Soft, beef-flavored chew that small dogs love—no messy topical treatments.
• Once-a-month dosing means no daily pills or frequent applications.

4. Vet-Recommended & Safe

• Approved by veterinarians for dogs weighing 4-8 lbs and at least 8 weeks old.
• Safe when used as directed, making parasite prevention stress-free.

How to Use NexGard PLUS 4-8 lbs Chews? (Dosage and Administration)

• One chew per month for dogs weighing 4-8 lbs.
• Give as a treat or with food—no need for special preparation.
• Always consult your veterinarian for exact dosage instructions depending on your pet's condition.

When to Start?

• Start using NexGard PLUS as soon as flea and tick season begins.
• If transitioning from another flea or heartworm medication, consult your vet for guidance.

What Are the Active Ingredients in NexGard PLUS for Small Dogs?

These three ingredients work together to provide full-spectrum parasite protection, ensuring your small dog stays healthy year-round.

NexGard PLUS vs. Regular NexGard – What’s the Difference?

Many pet owners wonder if NexGard PLUS is the same as regular NexGard. Here’s how they compare:

Which One Should You Choose?

• If you need flea & tick protection only, regular NexGard is sufficient.
• If you want comprehensive parasite protection, NexGard PLUS is the better choice.

Natural Remedies vs. NexGard PLUS – Are Natural Flea Treatments Effective?

Many pet owners explore natural flea remedies, such as:

• Apple cider vinegar
• Essential oils (like lavender or peppermint)
• Diatomaceous earth

However, natural remedies are NOT as effective as NexGard PLUS. They may repel some fleas but do not kill them or provide lasting protection. NexGard PLUS is clinically proven to eliminate parasites and prevent infestations—something natural remedies cannot guarantee.

For best results, stick to vet-recommended flea and tick treatments like NexGard PLUS.

Are There Any Side Effects of NexGard PLUS Chews 4-8 lbs?

Most dogs tolerate NexGard PLUS well, but some mild side effects may occur, including:

• Vomiting
• Diarrhea
• Lethargy
• Loss of appetite
• Skin irritation

If severe reactions occur, such as excessive drooling, seizures, or difficulty breathing, contact your veterinarian immediately.

What Precautions Should You Take When Using NexGard PLUS?

• For small dogs (4-8 lbs) only – Do not give to dogs under 4 lbs.
• Not for human use – Keep out of reach of children.
• Use with caution in dogs with a history of seizures.
• Consult your vet before use if your dog is pregnant, breeding, or has an underlying health condition.

How to Store NexGard PLUS for Dogs?

To maintain effectiveness, store NexGard PLUS:

• At room temperature (below 86°F/30°C)
• In a dry place, away from moisture and direct sunlight
• Out of reach of children and pets

Do not use expired medication, as it may not work as intended.

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

NexGard PLUS Chews for Small Dogs FAQs

What is NexGard PLUS used for?

NexGard PLUS is used for flea, tick, heartworm, and intestinal parasite prevention in small dogs weighing 4-8 lbs. It kills fleas and ticks, prevents heartworm disease, and treats roundworms and hookworms in a single, monthly chew.

How long does NexGard PLUS take to work?

NexGard PLUS starts killing fleas within 6 hours and ticks within 24 hours. It provides 30 days of continuous protection against parasites.

Can I use NexGard PLUS for puppies?

Yes, NexGard PLUS is safe for puppies as young as 8 weeks old, as long as they weigh at least 4 lbs. Always follow the recommended dosage based on your dog's weight.

Can I Buy NexGard PLUS Without a Vet Prescription?

No, NexGard PLUS requires a veterinarian’s prescription. This ensures your dog gets the correct dose and protection for their specific health needs.

To purchase NexGard PLUS, you’ll need:

• A valid prescription from your veterinarian
• Your dog’s weight and health history

You can order it from HardyPaw once you have a prescription!

Can I Give NexGard PLUS to Pregnant or Nursing Dogs?

NexGard PLUS has not been fully tested in pregnant or lactating dogs. While no serious risks have been reported, always consult your veterinarian before giving NexGard PLUS to a pregnant or nursing dog.

Is NexGard PLUS Safe for Dogs with Seizures?

NexGard PLUS contains Afoxolaner, which has been associated with neurological side effects in some dogs, including those with a history of seizures. While many dogs tolerate NexGard PLUS well, it’s not recommended for dogs with a history of epilepsy or seizures unless your vet approves it.

If your dog has neurological conditions, consult your veterinarian about alternative parasite protection options.

Does NexGard PLUS Kill Flea Eggs and Larvae?

Yes! NexGard PLUS works by killing fleas before they lay eggs, effectively stopping the flea life cycle. However, it does not kill flea eggs or larvae directly—instead, it prevents new infestations by eliminating adult fleas before they reproduce. For heavy infestations, use environmental flea control methods like vacuuming, washing bedding, and using flea sprays in your home.

Clinical Research

• https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-024-06603-z
• https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/14288
• https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1eb7bc46-cac9-47d2-bbdc-6801690dfbc4