Apoquel (oclacitinib) Tablets, 5.4 mg

Apoquel 5.4 mg Tablets for Dogs – Fast-Acting Itch and Allergy Relief

Apoquel 5.4 mg tablets are a prescription medication designed to relieve itching and inflammation caused by allergic dermatitis and atopic dermatitis in dogs. This fast-acting oral tablet works by selectively inhibiting Janus kinase (JAK) enzymes, which are responsible for transmitting itch and inflammation signals in the immune system. By blocking these pathways, Apoquel provides relief within 4 hours and helps manage chronic skin allergies without the side effects commonly associated with steroids.

Unlike corticosteroids or antihistamines, Apoquel effectively reduces symptoms of seasonal, environmental, and food allergies, allowing dogs to experience a better quality of life. Whether your dog suffers from pollen allergies, flea allergies, or contact dermatitis, Apoquel 5.4 mg is a trusted solution for long-term dermatological care.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.

Also Available In:

Apoquel is available in different strengths to suit dogs of various sizes and needs. Choose the right dosage based on your veterinarian’s recommendation:

• Apoquel Tablets for Dogs 3.6mg – Ideal for small dogs needing effective allergy and itch relief.
• Apoquel Tablets for Dogs 16mg – Best suited for large dogs requiring stronger dosage control.

Select the appropriate Apoquel strength for your dog and help them live an itch-free, happy life! 

What Are the Benefits of Apoquel 5.4 mg Tablets for Dogs?

Apoquel is a veterinarian-recommended treatment that provides several benefits for dogs suffering from pruritus (itchiness) and allergic skin conditions:

✅ Fast-Acting Itch Relief – Starts working within 4 hours and provides complete relief in 24 hours.
✅ Selective Immune Modulation – Targets JAK-1 and JAK-3 enzymes, reducing inflammatory cytokines without affecting overall immune function.
✅ Steroid-Free Treatment – Unlike prednisone or cyclosporine, Apoquel minimizes side effects like excessive thirst, weight gain, or mood changes.
✅ Long-Term Allergy Control – Safely used for extended periods without suppressing adrenal function like corticosteroids.
✅ Versatile Allergy Management – Effective against environmental allergens (pollen, dust mites), food allergies, and flea allergy dermatitis.
✅ Improves Skin Healing – Reduces constant scratching, chewing, and licking, allowing the skin barrier to restore itself naturally.

Apoquel 5.4 mg is ideal for dogs weighing 6.6-19.9 lbs experiencing moderate to severe allergic reactions.

How to Use Apoquel 5.4 mg for Dogs?

Dosage and Administration

• Initial Treatment – Administer twice daily for up to 14 days.
• Maintenance Dose – After 14 days, reduce to once daily for ongoing allergy relief.
• Can be given with or without food for ease of administration.
• Always follow your veterinarian’s dosage instructions based on your dog's weight.

💡 Tip: If you miss a dose, administer it as soon as possible. If it's close to the next scheduled dose, skip the missed dose and continue with the regular schedule.

What Are the Active Ingredients in Apoquel 5.4 mg?

Apoquel contains Oclacitinib maleate (5.4 mg) as the active ingredient, a Janus kinase (JAK) inhibitor that blocks itch-inducing and inflammatory cytokines, such as Interleukin-31 (IL-31).

Inactive Ingredients:

• Microcrystalline cellulose – A stabilizing agent.
• Lactose monohydrate – A filler to aid tablet formulation.
• Croscarmellose sodium – Helps the tablet dissolve quickly for fast absorption.
• Magnesium stearate – A lubricant to ensure proper tablet consistency.

Are There Any Side Effects of Apoquel 5.4 mg Tablets?

Apoquel is well-tolerated in most dogs, but some may experience mild or rare side effects, including:

🔹 Gastrointestinal upset – Occasional vomiting or diarrhea (usually resolves on its own).
🔹 Increased susceptibility to infections – Due to immune modulation, some dogs may develop minor skin or ear infections.
🔹 Lethargy or decreased appetite – Rare but possible in sensitive dogs.

🚨 When to Contact Your Veterinarian:

• Persistent vomiting, diarrhea, or loss of appetite.
• Unusual skin infections, swelling, or new growths.
• Signs of respiratory infections (coughing, sneezing).

What Are the Warnings and Precautions for Apoquel Use?

⚠ Not for Puppies Under 12 Months: Apoquel should only be used in adult dogs due to potential immune system effects.
⚠ Avoid in Dogs with Cancer or Serious Infections: Since Apoquel modulates immune function, it is not recommended for dogs with pre-existing immune-related conditions.
⚠ Use with Caution in Pregnant or Nursing Dogs: The safety of Apoquel in breeding dogs has not been fully established.
⚠ Potential Drug Interactions: Do not use Apoquel with other immunosuppressants (such as cyclosporine or corticosteroids) without veterinary supervision.

Shipping & Returns 

Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

FAQs - Apoquel 5.4 mg Tablets for Allergic Dermatitis in Dogs

Can Apoquel 5.4 mg be used for all dog breeds?

Yes, Apoquel 5.4 mg is safe for all dog breeds, but it should only be used in dogs over 12 months old. The dosage depends on the dog's weight, not breed. Always consult your veterinarian before starting treatment to ensure it’s appropriate for your dog’s specific health needs.

Does Apoquel treat ear infections caused by allergies?

Apoquel helps reduce inflammation and itching associated with allergic ear infections, but it does not directly treat bacterial or yeast infections. If your dog has recurrent ear infections, a vet may prescribe additional medications such as antifungals or antibiotics alongside Apoquel.

Can Apoquel be stopped suddenly, or should it be tapered?

Apoquel does not require tapering and can be stopped suddenly without withdrawal effects. However, discontinuing use may cause allergy symptoms to return. If you plan to stop Apoquel, consult your veterinarian to discuss alternative treatments for managing your dog’s allergies.

Is Apoquel safe for long-term use in senior dogs?

Apoquel is generally safe for long-term use in senior dogs, but older dogs may have a higher risk of infections due to immune modulation. Regular veterinary checkups are recommended to monitor for potential side effects, including changes in liver or kidney function over time.

Can Apoquel be used alongside allergy shots or immunotherapy?

Yes, Apoquel can be used with allergy shots (immunotherapy) as part of a comprehensive allergy management plan. It provides immediate itch relief while allergy shots work over time to build long-term tolerance to allergens. A veterinarian can determine the best combination for your dog.

Clinical Research

https://pubmed.ncbi.nlm.nih.gov/35300697/

https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-022-03210-x