Simparica for Dogs 44.1-88 lbs

Simparica Chews for Dogs (44.1-88 lbs)

Protection Against Fleas and Ticks

Simparica is a monthly chewable tablet that provides comprehensive protection for your dog against fleas and ticks. Containing the active ingredient sarolaner, Simparica swiftly eliminates existing infestations and delivers month-long defense, ensuring your canine companion remains comfortable and healthy. This treatment targets both fleas and multiple species of ticks, safeguarding your dog from the discomfort and potential diseases they carry.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.

Also Available in Other Sizes

Simparica chewable tablets come in multiple weight options to provide optimal flea and tick protection for dogs of all sizes. Choose the right size for your pet:

• Simparica for Puppies (2.8-5.5 lbs) – Ideal for extra small breed puppies.
• Simparica for Small Dogs (5.6-11 lbs) – Suitable for small breed dogs.
• Simparica for Medium Dogs (22.1-44 lbs) – Designed for medium-sized dogs.
• Simparica for Large Dogs (44.1-88 lbs) – Provides strong protection for larger breeds. (you are viewing this product)
• Simparica for Extra Large Dogs (88.1-132 lbs) – Perfect for giant breed dogs.

💡 Tip: Choosing the correct dosage ensures maximum effectiveness in flea and tick prevention. 

What are the Benefits of Simparica for Dogs?

• Fast-Acting Relief: Simparica starts killing fleas within 3 hours and ticks within 8 hours of administration, providing rapid relief from itching and discomfort.

• Month-Long Protection: Just one chewable tablet offers 30 days of continuous protection against fleas and ticks, simplifying your pet care routine.

• Broad-Spectrum Defense: Simparica is effective against multiple tick species, including American dog ticks, black-legged ticks, Gulf Coast ticks, and brown dog ticks. It also treats and prevents flea infestations.

• Convenient and Palatable: The chewable tablet is easily administered and highly palatable, making it a stress-free experience for both you and your dog.

• Breaks the Flea Life Cycle: Simparica kills fleas before they can lay eggs, preventing future infestations and keeping your home flea-free.

Simparica vs. Other Flea Tick Medicines

While other products offer flea and tick protection, Simparica stands out due to its:

• Speed of Action: Simparica's rapid onset of action provides quicker relief compared to some competitors.
• Comprehensive Tick Coverage: Simparica protects against a wide range of tick species, offering broader protection than some alternatives.
• Palatability: Simparica's chewable formulation is highly palatable, ensuring easy administration, unlike some less appealing options.

What are the Ingredients in Simparica?

• Active ingredient in Simparica: Sarolaner
• Inactive ingredients include: Lactose monohydrate, powdered cellulose, sodium starch glycolate, magnesium stearate, maize starch, sucrose, glucose liquid, dried porcine liver powder, soya protein concentrate, dibasic calcium phosphate anhydrous, propylene glycol, gallic acid, butylated hydroxytoluene, and red ferric oxide.

How Does Simparica Work to Eliminate Fleas and Ticks?

Simparica contains sarolaner, an isoxazoline parasiticide. Isoxazoline works by blocking nerve signals in fleas and ticks, leading to their paralysis and death.

• Targeting the Nervous System: Sarolaner selectively inhibits the arthropod's nervous system function by acting as an antagonist at ligand-gated chloride channels, specifically gamma-aminobutyric acid (GABA) receptors and glutamate receptors.

• Selective Toxicity: Sarolaner exhibits a higher affinity for insect and arachnid receptors compared to mammalian receptors. This allows it to selectively target parasites without causing significant harm to the treated animal.

• Rapid Paralysis and Death: Once sarolaner binds to the target receptors in the nervous system of fleas and ticks, it disrupts the normal flow of chloride ions into nerve cells. This disruption leads to hyperexcitation, paralysis, and ultimately the death of the parasite.

• Systemic Distribution: After oral administration, sarolaner is rapidly absorbed into the bloodstream and distributed throughout the body, ensuring that it reaches parasites that may be present on various parts of the animal's body.

What Types of Fleas and Ticks Does Simparica Protect Against?

Simparica is effective against:

• Fleas (Ctenocephalides felis)

• American dog tick (Dermacentor variabilis)

• Black-legged tick/Deer tick (Ixodes scapularis)

• Gulf Coast tick (Amblyomma maculatum)

• Brown dog tick (Rhipicephalus sanguineus)

• Lone Star tick (Amblyomma americanum)

Here's a table summarizing the protection:

Are There Any Potential Side Effects of Simparica?

In clinical trials, the most common side effects reported were:

• Vomiting
• Diarrhea
• Lethargy
• Anorexia
• Seizures

While generally safe, Simparica, like all medications, may cause side effects in some dogs. If you notice any unusual behavior or signs of illness after administering Simparica, contact your veterinarian immediately.

What Warnings and Precautions Should I Be Aware Of?

• Simparica is for use in dogs only. Do not use in cats or other animals.
• Keep out of reach of children.
• Simparica should not be used in puppies less than 6 months of age.
• Use with caution in dogs with a history of seizures or neurological disorders, as isoxazoline-class drugs have been associated with neurologic adverse reactions.
• The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs.
• Store at or below 30°C (86°F).

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Simparica for Dogs FAQs 

What is Simparica used for?
Simparica is a chewable tablet that protects dogs from fleas and ticks for 35 days. It kills fleas quickly and prevents tick-borne diseases.

How quickly does Simparica start working?
Simparica starts killing fleas within 3 hours and ticks within 8 hours after administration, providing fast relief for your dog.

Can Simparica be given with or without food?
Yes, Simparica can be administered with or without food, making it convenient to give to your dog.

What should I do if my dog vomits after taking Simparica?
Contact your veterinarian. They can advise you on whether to administer another dose or monitor your dog for any adverse reactions.

Is Simparica safe for all dogs?
Simparica is not recommended for puppies under 6 months old or dogs with a history of seizures. Consult your vet for appropriate flea and tick control options.

High Authority Resources:

• Fleas - Centers for Disease Control and Prevention (CDC)
• Ticks - Centers for Disease Control and Prevention (CDC)
• Sarolaner - European Medicines Agency (EMA)