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Nutramax Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe)

$435.00

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Nutramax SKU: DEN425 Barcode: 755970614305

4.7 / 5.0 based on 3 reviews
Size: 1 pack (30 tablets)

Nutramax Denosyl for Large Dogs

Supporting Optimal Liver and Brain Function

Nutramax Denosyl is a veterinary-recommended nutritional supplement meticulously formulated to support liver and brain health in large breed dogs. Denosyl contains S-Adenosylmethionine (SAMe), a naturally occurring molecule critical for various biochemical reactions in the body. This supplement aids in maintaining healthy liver function, supporting detoxification processes, and promoting overall cognitive well-being in your canine companion. It is commonly used to address age-related cognitive decline and support liver health against various stressors.

What are the Benefits of Denosyl for Large Dogs?

  • Supports Liver Health: Denosyl helps maintain healthy liver function by increasing hepatic glutathione levels, a powerful antioxidant that protects liver cells from damage.

  • Promotes Brain Health: The supplement supports cognitive function and helps mitigate age-related cognitive decline in senior dogs.

  • Antioxidant Protection: Denosyl aids in reducing oxidative stress in the liver and brain, protecting cells from free radical damage.

  • Supports Detoxification: By supporting liver function, Denosyl aids in the natural detoxification processes of the body.

  • May improve overall well being: Supplementation with Denosyl may lead to noticeable improvements in your dog's energy levels and appetite if liver function was previously compromised.

What Conditions Can Denosyl Help Manage in Large Dogs?

Denosyl is often recommended by veterinarians to support dogs with the following conditions:

  • Liver Disease: Including hepatitis, cirrhosis, and other forms of liver dysfunction.

  • Cognitive Dysfunction Syndrome (CDS): Helping to manage symptoms of age-related cognitive decline.

  • Elevated Liver Enzymes: As indicated by blood tests.

  • Exposure to Toxins or Medications: That can impact liver health.

What are the Ingredients in Nutramax Denosyl?

The active ingredient in Denosyl is S-Adenosylmethionine (SAMe).

Inactive Ingredients: Mannitol, Croscarmellose Sodium, Magnesium Stearate, Povidone, and Silicon Dioxide.

What is S-Adenosylmethionine (SAMe) and Why is it Important?

S-Adenosylmethionine, often shortened to SAMe, is a naturally occurring compound found in every cell of the body. It plays a critical role in numerous biochemical reactions, including:

  • Transmethylation: The transfer of methyl groups, which is essential for DNA and protein function.

  • Transsulfuration: The synthesis of glutathione, a crucial antioxidant for liver health.

  • Aminopropylation: The synthesis of polyamines, which are involved in cell growth and differentiation.

In the liver, SAMe is vital for maintaining cell function, detoxification, and the production of other important molecules. Supplementing with Denosyl helps increase SAMe levels, particularly when the liver is stressed or damaged.

How to Administer Denosyl to Your Large Dog

  1. Administer Denosyl tablets on an empty stomach, at least one hour before or two hours after a meal, for optimal absorption.

  2. Tablets should be given whole and not crushed or broken.

  3. Follow your veterinarian's specific dosage recommendations based on your dog's weight and condition.

  4. Ensure your dog has access to fresh water at all times.

Dosage and Administration:

Always consult your veterinary for exact dosage instructions depending on your pet's condition.

Here is a general dosing guideline:

Weight of Dog Dosage
56-85 lbs (25.5-38.6 kg) Two 225mg tablets daily
86-120 lbs (39-54.5 kg) Three 225mg tablets daily
Over 120 lbs (Over 54.5 kg) Four 225mg tablets daily
  • Important Note: The above table is a general guideline. Your veterinarian may adjust the dosage based on your dog's individual needs and health status.


Are There Any Potential Side Effects of Denosyl?

Denosyl is generally considered safe for dogs. However, in some cases, mild side effects may occur:

  • Gastrointestinal Upset: Some dogs may experience vomiting, diarrhea, or loss of appetite.

  • Lethargy: In rare cases, dogs may seem more tired than usual.

If you notice any concerning side effects, discontinue use and consult your veterinarian.

What Warnings Should I Be Aware of Before Using Denosyl?

  • Consult Your Veterinarian: Before starting Denosyl, consult your veterinarian to ensure it is appropriate for your dog, especially if they have pre-existing health conditions or are taking other medications.

  • Not for Use in Pregnant or Lactating Animals: The safety of Denosyl has not been evaluated in pregnant or lactating animals.

  • Keep Out of Reach of Children: This product is for animal use only.

  • Storage: Store in a cool, dry place, away from direct sunlight. Keep the blister pack intact until used.

How Does HardyPaw Ensure the Quality of Nutramax Denosyl?

At HardyPaw, we are committed to providing only the highest quality products for your pets. We source our Nutramax Denosyl directly from the manufacturer and store it under optimal conditions to ensure its potency and efficacy. Each batch is carefully inspected to meet our stringent quality standards, giving you peace of mind knowing you're providing your dog with a safe and effective supplement.

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Denosyl for Large Dogs FAQs

What are the early signs of liver problems in dogs?

Look for reduced appetite, vomiting, increased thirst/urination, lethargy, or jaundice (yellowing). See a vet if concerned.

How long does it take to see results from Denosyl?

Some dogs show improvement in weeks; allow 1-3 months. Regular vet checkups are key.

Can I split the Denosyl dosage into multiple times a day?

Discuss splitting dosages with your vet. Consistent timing, ideally on an empty stomach, is usually best.

Does Denosyl require a prescription?

No, Denosyl is available over-the-counter, but consult your vet before use.

Is Denosyl a cure for liver disease?

Denosyl is a supplement to support liver health. It's not a cure but can help manage liver conditions when part of a vet-guided treatment plan.

Clinical Research

https://pmc.ncbi.nlm.nih.gov/articles/PMC3039909/

Customer Reviews

Based on 3 reviews
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J
Joanl
Reduces my dogs elevated liver enzymes

Since using Denosyl, we have been able to keep my young golden retriever at a normal liver enzyme level. Whenever we discontinue this, they go back up. So glad this is an easy fix.

T
Tina
Better price than the Vet

So glad I discovered this at Hardypaw at a much lower price than the Vet charges. The vet was having an issue getting it in stock so I went searching online. Discovered at Hardypaw and no need for a script. No issues with stock and got it in a couple of days. My dog's vet had recommended this supplement because some of my dog's liver enzyme values are high. She has had several rounds of bloodwork, an ultrasound, and a liver biopsy. We still do not have an answer. Her levels have not gone down nor have they gone up. So, I cannot really say if it is actually helping but Vet recommended and I trust my Vet.

W
Werner Schneider

Excellent