Norfenicol (Florfenicol) – Respiratory Treatment for Cattle

Norfenicol (Florfenicol) Solution is a fast-acting, broad-spectrum antibiotic for the treatment of bovine respiratory disease (BRD) in beef and dry dairy cattle. Containing florfenicol as an active component, injectable Norfenicol Solution attacks bacterial infections caused by Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni. Norfenicol gives a powerful alternative to traditional antibiotics with a wide range of dosing. Having no milk withdrawal requirement for non-lactating cows, it is a veterinarian and rancher's top choice to ensure herd health and productivity are retained.

Benefits:

• Broad-Spectrum Antibiotic – Effectively cures BRD and secondary bacterial infections.
• Fast-Acting Formula – Determines and works to combat pathogenic bacteria to enable faster recovery.
• Flexible Dosing Regimens – Can be administered as single-dose or multidose therapy.
• No Milk Withdrawal for Non-Lactating Dairy Cattle – Ideal for use in beef and non-lactating dairy herds.
• Veterinarian-Trusted Treatment – Effective against major respiratory pathogens.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

How is Norfenicol given?

Norfenicol is given as an intramuscular (IM) or subcutaneous (SC) injection, depending on the severity of the infection. Always follow veterinary instructions for use.

What is Norfenicol used to treat?

It is widely used to manage bovine respiratory disease (BRD) caused by Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni infections, which have the potential to impair cattle productivity and health.

Dosage & Administration:

For treatment of bovine respiratory disease (BRD) and bovine interdigital phlegmon (foot rot): Norfenicol Injectable Solution should be administered by intramuscular injection to cattle at a dose rate of 20 mg/kg body weight (3 mL/100 lbs). A second dose should be administered 48 hours later. Alternatively, Norfenicol Injectable Solution can be administered by a single subcutaneous (SC) injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck.

NOTE: Intramuscular injection may result in local tissue reaction that persists beyond 28 days. This may result in trim loss of edible tissue at slaughter. Tissue reaction at injection sites other than the neck is likely to be more severe.

For control of respiratory disease in cattle at high risk of developing BRD: Norfenicol Injectable Solution should be administered by a single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck.

NORFENICOL INJECTABLE SOLUTION DOSAGE GUIDE

Do not inject more than 10 mL per injection site.

Clinical improvement should be evident in most treated subjects within 24 hours of initiation of treatment. If a positive response is not noted within 72 hours of initiation of treatment, the diagnosis should be re-evaluated.

Contraindications:

Do not use in animals that have shown hypersensitivity to florfenicol.

Warnings:

Not For Human Use. Keep Out of Reach of Children. This product contains materials that can be irritating to the skin and eyes. Avoid direct contact with skin, eyes, and clothing. In case of accidental eye exposure, flush with water for 15 minutes. In case of accidental skin exposure, wash with soap and water. Remove contaminated clothing. Consult a physician if irritation persists. Accidental injection of this product may cause local irritation. Consult a physician immediately. The Safety Data Sheet (SDS) contains more detailed occupational safety information.

To report suspected adverse drug events, for technical assistance or to obtain a copy of the Safety Data Sheet (SDS), contact Norbrook at 1-866-591-5777.

Precautions:

Not for use in animals intended for breeding purposes. The effects of florfenicol on bovine reproductive performance, pregnancy, and lactation have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Intramuscular injection may result in local tissue reaction which persists beyond 28 days. This may result in trim loss of edible tissue at slaughter. Tissue reaction at injection sites other than the neck is likely to be more severe.

Residue Warnings:

Animals intended for human consumption must not be slaughtered within 28 days of the last intramuscular treatment. Animals intended for human consumption must not be slaughtered within 33 days of subcutaneous treatment. This product is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows. A withdrawal period has not been established in pre-ruminating calves. Do not use in calves to be processed for veal.

Storage:

Store at or below 77°F (25°C). Refrigeration is not required. Excursions permitted up to 86° F (30° C). Brief exposure to temperatures up to 104° F (40° C) may be tolerated provided the mean kinetic temperature does not exceed 77° F (25° C); however, such exposure should be minimized. The solution is light yellow to straw-colored. Color does not affect potency.

Use within 28 days of the first vial puncture.

Shipping & Returns

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FAQ

For what indication is Norfenicol applied?

Norfenicol is applied to treat respiratory disorders in cattle like beef cattle and non-lactating dairy cattle as Bovine Respiratory Disease (BRD) due to bacteria sensitive to it.

What is the active compound in Norfenicol?

The active compound is Florfenicol, a veterinary antibiotic effective against bacterial infections in cattle.

What is the way of administration of Norfenicol?

It is administered by intramuscular (IM) or subcutaneous (SQ) injection, as directed by a veterinarian.

What is the dosage for Norfenicol?

The dosage will be different based on the severity of the infection and the weight of the cattle. Therefore, always adhere to the veterinarian’s instructions and product label for the actual dosage.

What is slaughter withdrawal time?

Norfenicol-treated cattle should not be slaughtered within 28 days from the last treatment for human consumption.

Is Norfenicol applicable to lactating dairy cows?

No, Norfenicol is not indicated in lactating dairy cows for human consumption.