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Laverdia-CA1 10mg (50 tablets)

$255.99

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Dechra SKU: LBL-7005-00

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Laverdia-CA1 10mg Tablets for Dogs (Verdinexor)

A Groundbreaking Oral Chemotherapy for Canine Lymphoma

Laverdia-CA1 (Verdinexor) 10mg Tablets is a pioneering oral anti-cancer medication designed to treat lymphoma in dogs. As the first FDA conditionally approved oral treatment for canine lymphoma, Laverdia-CA1 offers a non-invasive, at-home therapy option that improves quality of life and offers convenience for pet owners.

Targeting canine lymphoma, one of the most commonly diagnosed cancers in dogs, this medication uses the novel active compound verdinexor, which inhibits cancer cell proliferation while minimizing damage to healthy cells.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

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Shop Laverdia-CA1 in multiple strengths to match your dog’s treatment needs:

What Are the Benefits of Laverdia-CA1 (Verdinexor) 10mg Tablets for Dogs?

Laverdia-CA1 is a revolutionary development in veterinary oncology. Here's how it excels:

  • Targeted cancer treatment: Works by blocking XPO1 (Exportin-1), a protein responsible for transporting tumor suppressor proteins out of the cell nucleus, which helps kill cancer cells while sparing healthy ones.
  • Minimally invasive: Oral tablets allow in-home administration, reducing stressful clinic visits for pets.
  • FDA conditionally approved: The first-in-class Selective Inhibitor of Nuclear Export (SINE) drug approved for treating canine lymphoma.
  • Better quality of life: Studies show reduced cancer-related symptoms and longer remission in some dogs.
  • Customizable dosing: Based on body weight and health condition, offering flexibility in treatment plans.
  • Easy integration: Can be used as a standalone therapy or adjunct to traditional chemotherapy.

How Does Laverdia-CA1 Work in Canine Lymphoma?

Laverdia-CA1 targets and inhibits Exportin-1 (XPO1), a nuclear export protein that plays a critical role in cancer cell survival by expelling tumor suppressor proteins from the nucleus. By blocking this export pathway, verdinexor helps restore the function of natural tumor-suppressing proteins, leading to apoptosis (programmed cell death) in cancer cells.

Dosage and Administration Guidelines for Laverdia-CA1 10mg

Always consult your veterinary for exact dosage instructions depending on your pet's condition.

Typical administration includes:

  • Administer twice weekly (e.g., Monday & Thursday) with at least 72 hours between doses.
  • Dosing is weight-based, and tablets come in multiple strengths (10 mg, 50 mg, 100 mg).
  • Administer orally, with or without food.
  • Avoid contact with skin, eyes, and mucous membranes during handling.

What Are the Ingredients in Laverdia-CA1 for Dogs?

Component

Purpose

Verdinexor

Active ingredient; SINE compound that inhibits XPO1 to stop cancer progression

Inactive ingredients

Includes excipients used for tablet formulation

Verdinexor: A first-in-class Selective Inhibitor of Nuclear Export (SINE) that selectively targets cancerous cells without significantly harming healthy ones.

Are There Any Side Effects of Laverdia-CA1 Tablets?

While generally well tolerated, dogs may experience:

  • Vomiting
  • Diarrhea
  • Lethargy
  • Decreased appetite
  • Mild weight loss

Rare but serious side effects:

  • Neutropenia (low white blood cell count)
  • Thrombocytopenia (low platelet count)

💡 Prompt veterinary attention is advised if symptoms persist or worsen.

What Warnings Should You Know Before Using Laverdia-CA1?

  • Not intended for use in breeding, pregnant, or lactating dogs.
  • Keep out of reach of children and other animals.
  • Use protective gloves when handling tablets.
  • If you miss a dose, consult your vet—do not double dose.

Shipping & Returns

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Laverdia-CA1 10 mg Tablets FAQs

How fast does Laverdia-CA1 start working in dogs?

Most dogs begin to show symptom improvement within 1–2 weeks of consistent dosing, though response time varies based on lymphoma stage and overall health.

Can Laverdia-CA1 be used for other types of cancer in dogs?

Currently, Laverdia-CA1 is only conditionally approved for canine lymphoma. Off-label use for other cancers should only be done under strict veterinary supervision.

Is blood work needed before starting Laverdia-CA1?

Yes, baseline blood tests are required to assess liver, kidney, and immune function. Monitoring should continue throughout the treatment course.

Can Laverdia-CA1 be used alongside prednisone or other steroids?

Yes, in some cases vets may recommend prednisone or palliative medications to manage symptoms and inflammation alongside Laverdia.

Is Laverdia-CA1 safe for senior dogs?

Laverdia-CA1 can be used in senior dogs, but geriatric patients need close monitoring due to potential immune or organ sensitivity.

Authoritative Resources for Further Reading:

  1. FDA: Laverdia-CA1 Approval Overview
  2. VCA Animal Hospitals: Lymphoma in Dogs
  3. University of Wisconsin Veterinary Care – Oncology Services
  4. PetMD: Dog Cancer Overview