Antirobe (clindamycin hydrochloride) Capsules

Effective Treatment for Canine Bacterial Infections

Product Description

Antirobe Capsules are formulated with clindamycin hydrochloride, a lincosamide antibiotic prescribed for dogs. The capsules are used for treating skin infections, wounds, abscesses, dental infections, and osteomyelitis caused by bacteria that are sensitive to the medication. Clindamycin works by disrupting bacterial protein synthesis. This assists in managing infections and promoting recovery when administered according to a licensed veterinarian's instructions.

Please note that the product may arrive in a Hardy Paw Pharmacy vial; manufacturer packaging is shown for reference.

Benefits

• Antibacterial: Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit to control susceptible infections.
• Broad Clinical Indications: Indicated for skin infections, wounds, abscesses, dental infections, and osteomyelitis in dogs.
• Anaerobic Coverage: Effective against anaerobic pathogens, including Bacteroides fragilis and Clostridium perfringens.
• Flexible Variants: Available in 25 mg, 75 mg, and 150 mg variants to support flexible dosing.
• Rapid Oral Absorption: Rapidly absorbed from the gastrointestinal tract with measurable serum levels in dogs.

Variants

• 25 mg Capsules
• 75 mg Capsules
• 150 mg Capsules

Ingredients

Active Ingredients

Clindamycin hydrochloride equivalent to 25 mg, 75 mg, or 150 mg of clindamycin per capsule.

How to Use

Recommended-Dosage Chart

Dosage & Administration Instructions

• Prescription Required: The use of this medication is limited by Federal Law to administration by or under the directive of a licensed veterinarian.
• Dosage: Administer the recommended dosage orally twice a day.
• Weight-Dependent Dosage: Modify the strength of the dosage as per the dog's weight and severity of the condition.
• Treatment Duration: Do not extend treatment for acute infections beyond four days without observing a clinical response.
• Osteomyelitis Course: Continue osteomyelitis treatment for at least 28 days unless no therapeutic response occurs.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Long Term Monitoring: Perform periodic liver, kidney, and blood count tests during therapy exceeding one month.
• Hypersensitivity Risk: Do not use in dogs with known hypersensitivity to clindamycin or lincomycin preparations.
• Species Restriction: Avoid administration to rabbits, ruminants, hamsters, guinea pigs, horses, and chinchillas.
• Severe Organ Disease: Use only under veterinary care for canines with severe renal or hepatic disease and monitor serum levels.
• Neuromuscular Caution: Use with caution in animals receiving neuromuscular blocking agents due to potential interaction.

Possible Side Effects

• Vomiting Episodes: Occasional vomiting incidents were observed during clinical trials and post-approval use.
• Diarrhea Occurrence: Diarrhea has been observed as a potential adverse reaction during treatment.

Storage Information

• Room Temperature Storage: Store under controlled room temperature between 20-25 degrees Celsius.
• Child Safety: Not intended for human use. Always keep out of reach of children.

Frequently Asked Questions

Q1: What are Antirobe Capsules used for in dogs?

Ans: Antirobe Capsules are prescribed for treating skin infections, wounds, abscesses, dental infections, and osteomyelitis in dogs caused by susceptible bacteria. The active ingredient, clindamycin hydrochloride, works against specific aerobic and anaerobic pathogens when prescribed by a licensed veterinarian.

Q2: How do Antirobe Capsules work against bacterial infections?

Ans: Antirobe Capsules contain clindamycin, which is a lincosamide antibiotic that disrupts bacterial protein production by attaching to the 50S ribosomal subunit. This mechanism stops bacteria from reproducing, aiding in the management of infections in dogs that are susceptible when given as directed by a veterinarian.

Q3: What is the recommended dosage of Antirobe Capsules for dogs?

Ans: For infected wounds, abscesses, and dental infections, the recommended dosage is 2.5 to 15 mg/pound of body weight every 12 hours. For osteomyelitis, 5 to 15 mg per pound every 12 hours is recommended, as directed by a veterinarian.

Q4: Are there any side effects associated with Antirobe Capsules?

Ans: The most commonly reported side effects in dogs include vomiting and diarrhea. These reactions were observed during clinical trials and post-approval use. Pet owners should contact their veterinarian if adverse reactions occur during treatment.

Q5: Are Antirobe Capsules safe for all animals?

Ans: Antirobe Capsules are for use in dogs only and are contraindicated in animals with hypersensitivity to clindamycin or lincomycin. They should not be administered to rabbits, hamsters, guinea pigs, horses, chinchillas, or ruminating animals due to gastrointestinal risks.